Showing entry for (+)-Valine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003205
Compound Name(+)-Valine
Structure
FormulaC5H11NO2
InchiKeyKZSNJWFQEVHDMF-BYPYZUCNSA-N
SMILESCC(C)[C@H](N)C(O)=O
InchiInChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
IUPAC(2S)-2-amino-3-methylbutanoic acid
Molecular Weight117.15
Pubchem Id6287
Chembl IdCHEMBL43068
Targets of Information Source
DrugBank DB00161
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P05166 BXGT006335 Propionyl-CoA carboxylase beta chain, mitochondrial reviewed Enzyme PCCB approved; nutraceutical -
P54687 BXGT011067 Branched-chain-amino-acid aminotransferase, cytosolic reviewed Enzyme BCAT1 approved; nutraceutical -
P26640 BXGT009123 Valine--tRNA ligase reviewed - VARS approved; nutraceutical -
PDB VAL
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P00800 BXGT005661 Thermolysin reviewed npr - - - - -
Q16980 BXGT013689 Twitchin-like protein unreviewed - - - - -
P09954 BXGT006948 Carboxypeptidase A1 reviewed CPA1 - - - - -
P07824 BXGT006682 Arginase-1 reviewed Arg1 - - - - -
P56690 BXGT011191 Isoleucine--tRNA ligase reviewed ileS - - - - -
P0AD96 BXGT007279 Leu/Ile/Val-binding protein reviewed livJ - - - 4000 -
P13901 BXGT007965 Genome polyprotein reviewed - - - - -
Q9UI42 BXGT021713 Carboxypeptidase A4 reviewed CPA4 Enzyme - - - -
Q8TL28 BXGT018831 Ulilysin reviewed MA_3214 - - - - -
Q5SI02 BXGT015700 1-pyrroline-5-carboxylate dehydrogenase unreviewed TTHA1578 - - - - -
P39779 BXGT010137 GTP-sensing transcriptional pleiotropic repressor CodY reviewed codY - - - - -
P00760 BXGT005644 Cationic trypsin reviewed - - - - -
Q01693 BXGT012606 Bacterial leucyl aminopeptidase reviewed - - - - -
Q7CX36 BXGT016948 ABC transporter, substrate binding protein (Amino acid) unreviewed Atu2422 - - - - -
Q5SL42 BXGT015792 Probable branched-chain amino acid ABC transporter, amno acid binding protein unreviewed TTHA0451 - - - - -
Q11T61 BXGT013221 D-Ala-D/L-Ala epimerase reviewed tfdD - - - - -
V5YM14 BXGT022598 Dipeptidyl aminopeptidase BII reviewed dapb2 - - - - -
Q3MFZ5 BXGT014504 Amino acid/amide ABC transporter substrate-binding protein, HAAT family unreviewed Ava_0465 - - - - -
A0A0J9X1Z1 BXGT000509 Membrane-bound lytic murein transglycosylase F unreviewed CF510_16633 - - - - -
Q6WVP6 BXGT016599 Arginase unreviewed Smp_059980 - - - - -
A7Y7W1 BXGT001643 Periplasmic dipeptide-binding protein unreviewed dppA - - - - -
P12821 BXGT007849 Angiotensin-converting enzyme reviewed ACE Enzyme - - - -
Q9SKE2 BXGT021590 Jasmonoyl--L-amino acid synthetase JAR1 reviewed JAR1 - - - - -
Q70LM7 BXGT016682 Linear gramicidin synthase subunit A reviewed lgrA - - - - -
N1P8Q8 BXGT003874 Nta1p unreviewed CENPK1137D_1355 - - - - -
P0ADF8 BXGT007284 Acetolactate synthase isozyme 1 small subunit reviewed ilvN - - - - -
P0ADG0 BXGT007285 Acetolactate synthase isozyme 1 small subunit reviewed ilvN - - - - -
P43133 BXGT010359 Thermolysin reviewed nprS - - - - -
Q3K7T6 BXGT025274 Putative methyl-accepting chemotaxis protein unreviewed Pfl01_4431 - - - - -
P00772 BXGT005648 Chymotrypsin-like elastase family member 1 reviewed CELA1 - - - - -
P14618 BXGT008027 Pyruvate kinase PKM reviewed PKM Kinase - - - -
Q93YZ7 BXGT025867 Acetolactate synthase small subunit 2, chloroplastic reviewed At2g31810 - - - - -
Q0P864 BXGT013112 Putative methyl-accepting chemotaxis signal transduction protein unreviewed Cj1564 - - - - -
C7GQK9 BXGT025931 Acetohydroxy-acid synthase small subunit unreviewed ILV6 - - - - -
Q9HW02 BXGT025947 UDP-N-acetylmuramate--L-alanine ligase reviewed murC - - - - -
A0A4Y7X244 BXGT026014 Sodium-dependent transporter unreviewed E2L07_01100 - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL43068
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q91Y77 BXGT019323 Monocarboxylate transporter 10 reviewed - Slc16a10 Activity - - -
P46059 BXGT010500 Solute carrier family 15 member 1 reviewed Transporter SLC15A1 Ratio - - -
P46059 BXGT010500 Solute carrier family 15 member 1 reviewed Transporter SLC15A1 EC50 - - -
P46059 BXGT010500 Solute carrier family 15 member 1 reviewed Transporter SLC15A1 IC50 - - -
Q969S8 BXGT019613 Polyamine deacetylase HDAC10 reviewed Epigenetic regulator HDAC10 Activity '=' 100 %
Q9UKV0 BXGT021750 Histone deacetylase 9 reviewed Epigenetic regulator HDAC9 Activity '=' 100 %
P56524 BXGT011176 Histone deacetylase 4 reviewed Epigenetic regulator HDAC4 Activity '=' 100 %
Q96DB2 BXGT019639 Histone deacetylase 11 reviewed Epigenetic regulator HDAC11 Activity '=' 100 %
Q9BY41 BXGT020180 Histone deacetylase 8 reviewed Epigenetic regulator HDAC8 Activity '=' 100 %
Q8WUI4 BXGT018992 Histone deacetylase 7 reviewed Epigenetic regulator HDAC7 Activity '=' 100 %
Q9UQL6 BXGT021813 Histone deacetylase 5 reviewed Epigenetic regulator HDAC5 Activity '=' 100 %
Q92769 BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 Activity '=' 100 %
Q9UBN7 BXGT021658 Histone deacetylase 6 reviewed Epigenetic regulator HDAC6 Activity '=' 100 %
O15379 BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 Activity '=' 100 %
Q13547 BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 Activity '=' 100 %
P46059 BXGT010500 Solute carrier family 15 member 1 reviewed Transporter SLC15A1 max activation - - -
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Inhibition '=' 43 %
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 IC50 '=' 68000 nM
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 Inhibition '>=' 25 %
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Activity '=' 100 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00008 Garlic Allium sativum Herbs and Spices
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00052 Watermelon Citrullus lanatus Gourds
BXGF00181 Dandelion Taraxacum officinale Herbs and Spices
BXGF00200 Mung bean Vigna radiata Pulses
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF01140 Angelica gigas Angelica gigas Medicinal Plant
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01668 Taraxacum platycarpum Taraxacum platycarpum Medicinal Plant
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF02049 Angelica sinensis Angelica sinensis Medicinal Plant
BXGF02152 Taraxacum borealisinense Taraxacum borealisinense Others
BXGF02275 Trichosanthes kirilowii maxim Trichosanthes kirilowii maxim Others
BXGF02526 Santalum album Santalum album Medicinal Plant
BXGF03490 Atractylodes macrocephala koidz Atractylodes macrocephala koidz Others
BXGF03630 Taraxacum coreanum Taraxacum coreanum Others
BXGF04310 Taraxacum mongolicum Taraxacum mongolicum Medicinal Plant
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04842 Angelica acutiloba Angelica acutiloba Medicinal Plant
BXGF04889 Pogostemon cablin Pogostemon cablin Medicinal Plant
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF05203 Chlamydomonas reinhardtii Chlamydomonas reinhardtii Others
BXGF05297 Isatis tinctoria Isatis tinctoria Medicinal Plant
BXGF05330 Arum ternatum thunb Arum ternatum thunb Others
BXGF05421 Tussilago farfara Tussilago farfara Medicinal Plant
BXGF05842 Platycodon grandiforus Platycodon grandiforus Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease