acompound

Showing entry for 4'-Methylgenkwanin

General Compound Information
BXGC Id	BXGC0003804
Compound Name	4'-Methylgenkwanin
Structure
Formula	C17H14O5
InchiKey	LZERJKGWTQYMBB-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(OC)C=C2O1
Inchi	InChI=1S/C17H14O5/c1-20-11-5-3-10(4-6-11)15-9-14(19)17-13(18)7-12(21-2)8-16(17)22-15/h3-9,18H,1-2H3
IUPAC	5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Molecular Weight	298.29
Pubchem Id	5281601
Chembl Id	CHEMBL350958

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

23413

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006255	Alpha-amylase 1	reviewed		AMY1A	-	-	-	-
reviewed	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	-	27800	-	-

CHEMBL

CHEMBL350958

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P28593	BXGT009278	Trypanothione reductase	reviewed	-	TPR	Inhibition	'='	12	%
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	Displacement	'='	69	%
P30543	BXGT009437	Adenosine receptor A2a	reviewed	-	Adora2a	Displacement	'<'	10	%
P25099	BXGT009016	Adenosine receptor A1	reviewed	-	Adora1	Displacement	'<'	10	%
Q86831	BXGT017584	Polyprotein II	unreviewed	-		Inhibition	'='	54	%
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	-	-	-
P22460	BXGT008774	Potassium voltage-gated channel subfamily A member 5	reviewed	Ion channel	KCNA5	Inhibition	'<'	50	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00119	Sweet basil	Ocimum basilicum	Herbs and Spices
BXGF00159	Rosemary	Rosmarinus officinalis	Herbs and Spices
BXGF00165	Common sage	Salvia officinalis	Herbs and Spices
BXGF00966	Tristania conferta	Tristania conferta	Others
BXGF00972	Plectranthus myrianthus	Plectranthus myrianthus	Others
BXGF01024	Pentaclethra macrophylla	Pentaclethra macrophylla	Medicinal Plant
BXGF01035	Maackia tashiroi	Maackia tashiroi	Others
BXGF01085	Veronica polita	Veronica polita	Medicinal Plant
BXGF01183	Glycosmis macrophylla	Glycosmis macrophylla	Others
BXGF01250	Colchicum filifolium	Colchicum filifolium	Others
BXGF01253	Stephania zippeliana	Stephania zippeliana	Others
BXGF01256	Cynoglossum macrostylum	Cynoglossum macrostylum	Others
BXGF01329	Eucalyptus apodophylla	Eucalyptus apodophylla	Medicinal Plant
BXGF01416	Hypericum polyanthemum	Hypericum polyanthemum	Others
BXGF01418	Distephanus angulifolius	Distephanus angulifolius	Others
BXGF01480	Periploca sepium	Periploca sepium	Medicinal Plant
BXGF01548	Campylotropis hirtella	Campylotropis hirtella	Medicinal Plant
BXGF01685	Metanarthecium luteoviride	Metanarthecium luteoviride	Others
BXGF01686	Pulsatilla chinensis	Pulsatilla chinensis	Medicinal Plant
BXGF02098	Polytrichastrum alpinum	Polytrichastrum alpinum	Others
BXGF02167	Scutellaria barbata	Scutellaria barbata	Medicinal Plant
BXGF02206	Mucuna holtonii	Mucuna holtonii	Others
BXGF02233	Quercus marilandica	Quercus marilandica	Medicinal Plant
BXGF02318	Pandanus tectorius	Pandanus tectorius	Medicinal Plant
BXGF02446	Centaurea scoparia	Centaurea scoparia	Others
BXGF02633	Breonia chinensis	Breonia chinensis	Medicinal Plant
BXGF03021	Turnera diffusa	Turnera diffusa	Medicinal Plant
BXGF03054	Mimosa pigra	Mimosa pigra	Medicinal Plant
BXGF03103	Cheilanthes fragrans	Cheilanthes fragrans	Medicinal Plant
BXGF03239	Fadogia agrestis	Fadogia agrestis	Medicinal Plant
BXGF03289	Ostrya carpinifolia	Ostrya carpinifolia	Medicinal Plant
BXGF03305	Aconitum variegatum	Aconitum variegatum	Medicinal Plant
BXGF03432	Chrysanthemum indicum	Chrysanthemum indicum	Medicinal Plant
BXGF03477	Stephania dielsiana	Stephania dielsiana	Medicinal Plant
BXGF03518	Mentha cardiaca	Mentha cardiaca	Others
BXGF03527	Alpinia oxyphylla	Alpinia oxyphylla	Medicinal Plant
BXGF03601	Maclura cochinchinensis	Maclura cochinchinensis	Medicinal Plant
BXGF03637	Rhodiola semenovii	Rhodiola semenovii	Others
BXGF03872	Lycopodium japonicum	Lycopodium japonicum	Medicinal Plant
BXGF03921	Agave xylonacantha	Agave xylonacantha	Others
BXGF03987	Angelica saxatilis	Angelica saxatilis	Others
BXGF04035	Campanula choziatowskyi	Campanula choziatowskyi	Others
BXGF04056	Euphorbia latazi	Euphorbia latazi	Others
BXGF04208	Salvia patens	Salvia patens	Others
BXGF04214	Dialium excelsum	Dialium excelsum	Others
BXGF04380	Euphorbia hylonoma	Euphorbia hylonoma	Others
BXGF04409	Senecio platyphylloides	Senecio platyphylloides	Others
BXGF04418	Drymaria cordata	Drymaria cordata	Medicinal Plant
BXGF04442	Boesenbergia pandurata	Boesenbergia pandurata	Medicinal Plant
BXGF04447	Helleborus macranthus	Helleborus macranthus	Others
BXGF04448	Salix rosmarinifolia	Salix rosmarinifolia	Others
BXGF04455	Heliotropium scabrum	Heliotropium scabrum	Others
BXGF04457	Podocarpus dacrydioides	Podocarpus dacrydioides	Medicinal Plant
BXGF04469	Centaurea sonchifolia	Centaurea sonchifolia	Others
BXGF04472	Matricaria sabulosa	Matricaria sabulosa	Others
BXGF04489	Pterocaulon serrulatum	Pterocaulon serrulatum	Medicinal Plant
BXGF04504	Boswellia ovalifoliolata	Boswellia ovalifoliolata	Medicinal Plant
BXGF04506	Sarcococca saligna	Sarcococca saligna	Medicinal Plant
BXGF04515	Hardenbergia violacea	Hardenbergia violacea	Medicinal Plant
BXGF04529	Lonchocarpus chiricanus	Lonchocarpus chiricanus	Others
BXGF04533	Astragalus circassicus	Astragalus circassicus	Others
BXGF04541	Calophyllum inophyllum	Calophyllum inophyllum	Medicinal Plant
BXGF04543	Erythrina hypaphorus	Erythrina hypaphorus	Others
BXGF04548	Beilschmiedia madang	Beilschmiedia madang	Medicinal Plant
BXGF04555	Salvia lavanduloides	Salvia lavanduloides	Others
BXGF04573	Rubia akane	Rubia akane	Medicinal Plant
BXGF04586	Aniba santalodora	Aniba santalodora	Others
BXGF04618	Mentzelia decapetala	Mentzelia decapetala	Human Edible Plant
BXGF04648	Amorphophallus konjac	Amorphophallus konjac	Human Edible Plant
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04723	Afrocarpus gracilior	Afrocarpus gracilior	Others
BXGF04906	Andrographis herba	Andrographis herba	Others
BXGF04947	Derris indica	Derris indica	Medicinal Plant
BXGF04994	Anthemis cretica	Anthemis cretica	Medicinal Plant
BXGF05115	Andrographis paniculata	Andrographis paniculata	Medicinal Plant
BXGF05170	Crotalaria candicans	Crotalaria candicans	Others
BXGF05231	Salvia virgata	Salvia virgata	Human Edible Plant
BXGF05385	Eria japonica	Eria japonica	Others
BXGF05427	Salvia sessei	Salvia sessei	Others
BXGF05466	Juniperus drupacea	Juniperus drupacea	Medicinal Plant
BXGF05566	Petunia axillaris subsp. parodii	Petunia axillaris subsp. parodii	Medicinal Plant
BXGF05615	Ceropegia dichotoma	Ceropegia dichotoma	Garden Plant
BXGF05708	Ononis spinosa	Ononis spinosa	Medicinal Plant
BXGF05713	Antiphiona pinnatisecta	Antiphiona pinnatisecta	Others
BXGF05903	Crinum moorei	Crinum moorei	Others
BXGF05913	Eucalyptus globulus subsp. bicostata	Eucalyptus globulus subsp. bicostata	Medicinal Plant
BXGF06069	Dendrobium loddigesii	Dendrobium loddigesii	Medicinal Plant
BXGF06119	Gypsophila perfoliata	Gypsophila perfoliata	Others
BXGF06122	Bethencourtia palmensis	Bethencourtia palmensis	Others
BXGF06159	Pseudocyclosorus subochthodes	Pseudocyclosorus subochthodes	Others
BXGF06195	Pterocaulon virgatum	Pterocaulon virgatum	Medicinal Plant
BXGF06203	Lepechinia urbanii	Lepechinia urbanii	Others
BXGF06241	Vernonia cistifolia	Vernonia cistifolia	Others
BXGF06249	Enicosanthum cupulare	Enicosanthum cupulare	Others
BXGF06274	Sonneratia caseolaris	Sonneratia caseolaris	Medicinal Plant
BXGF06282	Daphne genkwa	Daphne genkwa	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}