Showing entry for Imidazole


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0005995
Compound NameImidazole
Structure
FormulaC3H4N2
InchiKeyRAXXELZNTBOGNW-UHFFFAOYSA-N
SMILESN1C=CN=C1
InchiInChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
IUPAC1H-imidazole
Molecular Weight68.08
Pubchem Id795
Chembl IdCHEMBL540
Targets of Information Source
DrugBank DB03366
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P40859 BXGT010203 Monomeric sarcosine oxidase reviewed - soxA experimental; investigational -
Q05603 BXGT012829 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase reviewed - cobT experimental; investigational -
P02144 BXGT005853 Myoglobin reviewed - MB experimental; investigational -
P35228 BXGT009800 Nitric oxide synthase, inducible reviewed - NOS2 experimental; investigational -
P54819 BXGT011084 Adenylate kinase 2, mitochondrial reviewed Kinase AK2 experimental; investigational -
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 experimental; investigational -
Q46822 BXGT014653 Isopentenyl-diphosphate Delta-isomerase reviewed - idi experimental; investigational -
P31677 BXGT009568 Trehalose-6-phosphate synthase reviewed - otsA experimental; investigational -
P17802 BXGT008343 Adenine DNA glycosylase reviewed - mutY experimental; investigational -
P31491 BXGT009545 YopE regulator reviewed - yerA experimental; investigational -
Q12965 BXGT013285 Unconventional myosin-Ie reviewed Cellular structure MYO1E experimental; investigational -
Q14565 BXGT013484 Meiotic recombination protein DMC1/LIM15 homolog reviewed - DMC1 experimental; investigational -
O34598 BXGT004486 Guanine deaminase reviewed - guaD experimental; investigational -
P26514 BXGT009118 Endo-1,4-beta-xylanase A reviewed - xlnA experimental; investigational -
P04252 BXGT006174 Bacterial hemoglobin reviewed - vhb experimental; investigational -
Q816R0 BXGT017299 Molybdenum cofactor biosynthesis protein B reviewed - moaB experimental; investigational -
P14739 BXGT008044 Uracil-DNA glycosylase inhibitor reviewed - UGI experimental; investigational -
Q9ZNA2 BXGT022471 Recombination protein RecR reviewed - recR experimental; investigational -
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed - LTA4H experimental; investigational -
P0ADA1 BXGT007280 Thioesterase 1/protease 1/lysophospholipase L1 reviewed - tesA experimental; investigational -
Q9NQX3 BXGT021172 Gephyrin reviewed - GPHN experimental; investigational -
P0A6B1 BXGT007041 Acyl carrier protein reviewed - acpP experimental; investigational -
P23222 BXGT008838 Sensor protein FixL reviewed - fixL experimental; investigational -
P99999 BXGT012235 Cytochrome c reviewed - CYCS experimental; investigational -
P74645 BXGT011739 Circadian clock protein KaiB reviewed - kaiB experimental; investigational -
P06988 BXGT006531 Histidinol dehydrogenase reviewed - hisD experimental; investigational -
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 7882
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT013665 Glutaminyl-peptide cyclotransferase reviewed Enzyme QPCT 100000 - - -
reviewed BXGT020253 Glutaminyl-peptide cyclotransferase reviewed Qpct 160000 - - -
reviewed BXGT022401 Gamma-aminobutyric acid type B receptor subunit 1 reviewed Gabbr1 229 - - -
reviewed BXGT022297 Histamine H3 receptor reviewed G-protein coupled receptor HRH3 >10000 - - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - >10000 - -
reviewed BXGT008976 Thromboxane-A synthase reviewed TBXAS1 - 670000 - -
reviewed BXGT013648 Prostacyclin synthase reviewed PTGIS - 4000000 - -
reviewed BXGT009355 Nitric oxide synthase, inducible reviewed Nos2 - 40000 - -
reviewed BXGT009353 Nitric oxide synthase, brain reviewed NOS1 175000 - - -
reviewed BXGT011858 Prostaglandin G/H synthase 2 reviewed PTGS2 - >10000000 - -
CHEMBL CHEMBL540
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Inhibition '=' 67 %
P07687 BXGT006658 Epoxide hydrolase 1 reviewed - Ephx1 E100 '=' 0 M
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 398 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 35481 nM
P29475 BXGT009353 Nitric oxide synthase, brain reviewed - NOS1 Ki '=' 175000 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 '=' 40000 nM
Q16647 BXGT013648 Prostacyclin synthase reviewed - PTGIS IC50 '=' 4000000 nM
P07687 BXGT006658 Epoxide hydrolase 1 reviewed - Ephx1 Log 1/E100 '=' 2 -
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 33491 nM
P79208 BXGT011858 Prostaglandin G/H synthase 2 reviewed - PTGS2 IC50 '>' 10000000 nM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '>' 10000000 nM
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 '=' 670000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '>' 10000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00819 Pulses Pulses
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease