Showing entry for 5,7-Dimethylchrysin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0008169
Compound Name5,7-Dimethylchrysin
Structure
FormulaC17H14O4
InchiKeyJRFZSUMZAUHNSL-UHFFFAOYSA-N
SMILESCOC1=CC(OC)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1
InchiInChI=1S/C17H14O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-10H,1-2H3
IUPAC5,7-dimethoxy-2-phenyl-4H-chromen-4-one
Molecular Weight282.29
Pubchem Id88881
Chembl IdCHEMBL275391
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50338972
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010897 Nuclear receptor subfamily 0 group B member 1 reviewed Nuclear receptor NR0B1 - >67615 - -
reviewed BXGT013335 Steroidogenic factor 1 reviewed Nuclear receptor NR5A1 - >67615 - -
reviewed BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 - 9200 - -
reviewed BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 - 11000 - -
CHEMBL CHEMBL275391
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 20596 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 22387 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 22387 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 1778 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 89125 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 112 %
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 28183 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 23099 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 25118 nM
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 IC50 '=' 9200 nM
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 8912 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 16353 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 2238 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 79432 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 56234 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 5358 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
P14916 BXGT008066 Urease subunit alpha reviewed - ureA IC50 '=' 2185000 nM
P69996 BXGT011656 Urease subunit beta reviewed - ureB IC50 '=' 2185000 nM
P38398 BXGT010037 Breast cancer type 1 susceptibility protein reviewed Enzyme BRCA1 Potency - 7943 nM
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 reviewed Nuclear receptor NR0B1 IC50 '>' 67615 nM
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 IC50 '=' 11000 nM
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial reviewed Kinase PDK1 Inhibition - - -
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 35481 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 103 %
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial reviewed Kinase PDK1 Inhibition '=' 5 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00038 Tea Camellia sinensis Teas
BXGF01227 Cyperus capitatus Cyperus capitatus Others
BXGF01250 Colchicum filifolium Colchicum filifolium Others
BXGF01256 Cynoglossum macrostylum Cynoglossum macrostylum Others
BXGF01384 Litsea nitida Litsea nitida Others
BXGF01667 Tripterygium wilfordii Tripterygium wilfordii Medicinal Plant
BXGF01686 Pulsatilla chinensis Pulsatilla chinensis Medicinal Plant
BXGF01934 Delphinium tricorne Delphinium tricorne Others
BXGF02014 Jatropha gossypiifolia Jatropha gossypiifolia Medicinal Plant
BXGF02023 Tamarix dioica Tamarix dioica Medicinal Plant
BXGF02077 Boronia alata Boronia alata Others
BXGF02102 Lobelia langeana Lobelia langeana Others
BXGF02206 Mucuna holtonii Mucuna holtonii Others
BXGF02226 Helleborus viridis Helleborus viridis Medicinal Plant
BXGF02233 Quercus marilandica Quercus marilandica Medicinal Plant
BXGF02271 Xanthium canadense Xanthium canadense Medicinal Plant
BXGF02324 Iris sibirica Iris sibirica Medicinal Plant
BXGF02391 Haemanthus albiflos Haemanthus albiflos Medicinal Plant
BXGF02413 Sibiraea angustata Sibiraea angustata Others
BXGF02444 Valeriana officinalis Valeriana officinalis Medicinal Plant
BXGF02446 Centaurea scoparia Centaurea scoparia Others
BXGF02467 Peltophorum dubium Peltophorum dubium Others
BXGF02501 Hordeum bulbosum Hordeum bulbosum Medicinal Plant
BXGF02584 Magnolia henryi Magnolia henryi Others
BXGF02628 Micromelum falcatum Micromelum falcatum Human Edible Plant
BXGF02660 Eria siamensis Eria siamensis Others
BXGF02700 Prunus pseudocerasus Prunus pseudocerasus Medicinal Plant
BXGF02714 Vernonia aurea Vernonia aurea Others
BXGF02799 Betula papyrifera Betula papyrifera Medicinal Plant
BXGF02873 Ephedra altissima Ephedra altissima Medicinal Plant
BXGF02894 Bignonia unguiscati Bignonia unguiscati Others
BXGF02904 Coronilla hyrcana Coronilla hyrcana Others
BXGF02921 Erica cinerea Erica cinerea Medicinal Plant
BXGF02943 Maytenus emarginata Maytenus emarginata Others
BXGF03047 Scutellaria indica Scutellaria indica Medicinal Plant
BXGF03054 Mimosa pigra Mimosa pigra Medicinal Plant
BXGF03103 Cheilanthes fragrans Cheilanthes fragrans Medicinal Plant
BXGF03239 Fadogia agrestis Fadogia agrestis Medicinal Plant
BXGF03289 Ostrya carpinifolia Ostrya carpinifolia Medicinal Plant
BXGF03305 Aconitum variegatum Aconitum variegatum Medicinal Plant
BXGF03477 Stephania dielsiana Stephania dielsiana Medicinal Plant
BXGF03601 Maclura cochinchinensis Maclura cochinchinensis Medicinal Plant
BXGF04035 Campanula choziatowskyi Campanula choziatowskyi Others
BXGF04208 Salvia patens Salvia patens Others
BXGF04214 Dialium excelsum Dialium excelsum Others
BXGF04380 Euphorbia hylonoma Euphorbia hylonoma Others
BXGF04409 Senecio platyphylloides Senecio platyphylloides Others
BXGF04418 Drymaria cordata Drymaria cordata Medicinal Plant
BXGF04442 Boesenbergia pandurata Boesenbergia pandurata Medicinal Plant
BXGF04447 Helleborus macranthus Helleborus macranthus Others
BXGF04448 Salix rosmarinifolia Salix rosmarinifolia Others
BXGF04455 Heliotropium scabrum Heliotropium scabrum Others
BXGF04457 Podocarpus dacrydioides Podocarpus dacrydioides Medicinal Plant
BXGF04469 Centaurea sonchifolia Centaurea sonchifolia Others
BXGF04472 Matricaria sabulosa Matricaria sabulosa Others
BXGF04489 Pterocaulon serrulatum Pterocaulon serrulatum Medicinal Plant
BXGF04504 Boswellia ovalifoliolata Boswellia ovalifoliolata Medicinal Plant
BXGF04515 Hardenbergia violacea Hardenbergia violacea Medicinal Plant
BXGF04529 Lonchocarpus chiricanus Lonchocarpus chiricanus Others
BXGF04533 Astragalus circassicus Astragalus circassicus Others
BXGF04543 Erythrina hypaphorus Erythrina hypaphorus Others
BXGF04548 Beilschmiedia madang Beilschmiedia madang Medicinal Plant
BXGF04555 Salvia lavanduloides Salvia lavanduloides Others
BXGF04573 Rubia akane Rubia akane Medicinal Plant
BXGF04586 Aniba santalodora Aniba santalodora Others
BXGF04618 Mentzelia decapetala Mentzelia decapetala Human Edible Plant
BXGF04648 Amorphophallus konjac Amorphophallus konjac Human Edible Plant
BXGF05231 Salvia virgata Salvia virgata Human Edible Plant
BXGF05232 Isolona pilosa Isolona pilosa Others
BXGF05566 Petunia axillaris subsp. parodii Petunia axillaris subsp. parodii Medicinal Plant
BXGF05677 Cinnamomum philippinense Cinnamomum philippinense Human Edible Plant
BXGF05822 Salvia miniata Salvia miniata Others
BXGF06122 Bethencourtia palmensis Bethencourtia palmensis Others
BXGF06162 Aeschynanthus parvifolius Aeschynanthus parvifolius Others
BXGF06203 Lepechinia urbanii Lepechinia urbanii Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease