Showing entry for Menatetrenone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0012321
Compound NameMenatetrenone
Structure
FormulaC31H40O2
InchiKeyDKHGMERMDICWDU-GHDNBGIDSA-N
SMILES[H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=CC=CC=C2C1=O)=C(\C)CCC=C(C)C
InchiInChI=1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+
IUPAC2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]-1,4-dihydronaphthalene-1,4-dione
Molecular Weight444.66
Pubchem Id5282367
Chembl IdCHEMBL259223
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL259223
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 31622 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 6510 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 3548 nM
P25779 BXGT009067 Cruzipain reviewed - IC50 '>' 200000 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 79432 nM
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase reviewed - GGCX Km '=' 13300 nM
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase reviewed - GGCX Activity - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 19952 nM
P25779 BXGT009067 Cruzipain reviewed - IC50 '=' 18000 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 5011 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Activity - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 25118 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 35481 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 39810 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 89125 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 79432 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 15811 nM
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase reviewed - GGCX Vmax/Km '=' 9 pmol/microM
Q8K1M6 BXGT018392 Dynamin-1-like protein reviewed - Dnm1l Inhibition - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 20596 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 44668 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 17782 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 17782 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Potency - 17782 nM
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 Activity - - -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 17782 nM
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase reviewed - GGCX Vmax '=' 126 pmol
Q8BX10 BXGT017927 Serine/threonine-protein phosphatase PGAM5, mitochondrial reviewed - Pgam5 Inhibition - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 26608 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 56234 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 56234 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 23715 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 10593 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 23109 nM
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 reviewed Enzyme modulator RAPGEF3 Potency - 7079 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 89125 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00101 Flaxseed Linum usitatissimum Herbs and Spices
BXGF00126 Millet Panicum miliaceum Cereals and cereal products
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00177 Sorghum Sorghum bicolor Cereals and cereal products
BXGF00272 Painted comber Serranus scriba Aquatic foods
BXGF00278 Beluga whale Delphinapterus leucas Aquatic foods
BXGF00299 Channel catfish Ictalurus punctatus Aquatic foods
BXGF00328 Eastern oyster Crassostrea virginica Aquatic foods
BXGF00343 Hippoglossus (Common halibut) Hippoglossus Aquatic foods
BXGF00389 Spotted seal Phoca largha Aquatic foods
BXGF00400 French plantain Musa X paradisiaca Fruits
BXGF00405 Quinoa Chenopodium quinoa Herbs and Spices
BXGF00407 Rainbow trout Oncorhynchus mykiss Aquatic foods
BXGF00413 Pink salmon Oncorhynchus gorbuscha Aquatic foods
BXGF00414 Chum salmon Oncorhynchus keta Aquatic foods
BXGF00416 Sockeye salmon Oncorhynchus nerka Aquatic foods
BXGF00417 Chinook salmon Oncorhynchus tshawytscha Aquatic foods
BXGF00429 Bearded seal Erignathus barbatus Aquatic foods
BXGF00455 Cattle (Beef, Veal) Bos taurus Animal foods
BXGF00462 Whitefish Coregonus Aquatic foods
BXGF00477 Smelt Osmeridae Aquatic foods
BXGF00489 Bivalvia (Clam, Mussel, Oyster) Bivalvia Aquatic foods
BXGF00491 Shrimp Caridea Aquatic foods
BXGF00493 Flatfish Pleuronectiformes Aquatic foods
BXGF00494 Domestic pig (Piglet, Pork) Sus scrofa domestica Animal foods
BXGF00505 Common mushroom Agaricus bisporus Vegetables
BXGF00574 Cheese Milk and milk products
BXGF00575 Milk (Cow) Milk and milk products
BXGF00576 Eggs Eggs
BXGF00594 Pizza Dishes
BXGF00609 Sausage Dishes
BXGF00625 Baby food Baby foods
BXGF00627 Soup Dishes
BXGF00636 Other candy Confectioneries
BXGF00642 Chocolate Cocoa and cocoa products
BXGF00666 Processed cheese Milk and milk products
BXGF00669 Dulce de leche Confectioneries
BXGF00671 Sweet custard Confectioneries
BXGF00672 Egg roll Dishes
BXGF00679 Stew Dishes
BXGF00689 Pudding Confectioneries
BXGF00692 Meatloaf Dishes
BXGF00710 Other sandwich Dishes
BXGF00714 Macaroni and cheese Dishes
BXGF00724 Cold cut Dishes
BXGF00734 Pie crust Baking goods
BXGF00736 Pie Confectioneries
BXGF00745 Ravioli Dishes
BXGF00749 Tamale Dishes
BXGF00782 Pupusa Dishes
BXGF00783 Empanada Dishes
BXGF00784 Arepa Dishes
BXGF00789 Other dish Dishes
BXGF00790 Pot pie Dishes
BXGF00797 Margarine-like spread Fats and oils
BXGF00844 Cow milk, pasteurized, vitamin D added, 3.25% fat Milk and milk products
BXGF02368 Amorpha fruticosa Amorpha fruticosa Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease