acompound

Showing entry for 5,7-Dihydroxy-3,3',4',6-Tetramethoxyflavone

General Compound Information
BXGC Id	BXGC0014531
Compound Name	5,7-Dihydroxy-3,3',4',6-Tetramethoxyflavone
Structure
Formula	C19H18O8
InchiKey	SDTFURCSGWUESP-UHFFFAOYSA-N
SMILES	COc1cc(ccc1OC)c1oc2cc(O)c(c(c2c(=O)c1OC)O)OC
Inchi	InChI=1S/C19H18O8/c1-23-11-6-5-9(7-12(11)24-2)17-19(26-4)16(22)14-13(27-17)8-10(20)18(25-3)15(14)21/h5-8,20-21H,1-4H3
IUPAC	2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-3,6-dimethoxychromen-4-one
Molecular Weight	374.1
Pubchem Id	5379563
Chembl Id	CHEMBL3407748

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL3407748

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9BUF5	BXGT020135	Tubulin beta-6 chain	reviewed	Cellular structure	TUBB6	Inhibition	'='	75	%
Q9BVA1	BXGT020142	Tubulin beta-2B chain	reviewed	-	TUBB2B	Inhibition	'='	75	%
Q13885	BXGT013400	Tubulin beta-2A chain	reviewed	Cellular structure	TUBB2A	Inhibition	'='	75	%
Q6PEY2	BXGT016465	Tubulin alpha-3E chain	reviewed	Cellular structure	TUBA3E	Inhibition	'='	75	%
Q9BQE3	BXGT020109	Tubulin alpha-1C chain	reviewed	Cellular structure	TUBA1C	Inhibition	'='	75	%
P68363	BXGT011594	Tubulin alpha-1B chain	reviewed	Cellular structure	TUBA1B	Inhibition	'='	75	%
P07437	BXGT006624	Tubulin beta chain	reviewed	Cellular structure	TUBB	Inhibition	'='	75	%
Q3ZCM7	BXGT014551	Tubulin beta-8 chain	reviewed	-	TUBB8	Inhibition	'='	75	%
P04350	BXGT006193	Tubulin beta-4A chain	reviewed	Cellular structure	TUBB4A	Inhibition	'='	75	%
Q71U36	BXGT016705	Tubulin alpha-1A chain	reviewed	Cellular structure	TUBA1A	Inhibition	'='	75	%
Q13509	BXGT013366	Tubulin beta-3 chain	reviewed	Cellular structure	TUBB3	Inhibition	'='	75	%
P68366	BXGT011595	Tubulin alpha-4A chain	reviewed	Cellular structure	TUBA4A	Inhibition	'='	75	%
P0DPH7	BXGT007527	Tubulin alpha-3C chain	reviewed	-	TUBA3C	Inhibition	'='	75	%
Q9H4B7	BXGT020475	Tubulin beta-1 chain	reviewed	Cellular structure	TUBB1	Inhibition	'='	75	%
P68371	BXGT011597	Tubulin beta-4B chain	reviewed	Cellular structure	TUBB4B	Inhibition	'='	75	%
Q9BUF5	BXGT020135	Tubulin beta-6 chain	reviewed	Cellular structure	TUBB6	IC50	'='	19300	nM
Q9BVA1	BXGT020142	Tubulin beta-2B chain	reviewed	-	TUBB2B	IC50	'='	19300	nM
Q13885	BXGT013400	Tubulin beta-2A chain	reviewed	Cellular structure	TUBB2A	IC50	'='	19300	nM
Q6PEY2	BXGT016465	Tubulin alpha-3E chain	reviewed	Cellular structure	TUBA3E	IC50	'='	19300	nM
Q9BQE3	BXGT020109	Tubulin alpha-1C chain	reviewed	Cellular structure	TUBA1C	IC50	'='	19300	nM
P68363	BXGT011594	Tubulin alpha-1B chain	reviewed	Cellular structure	TUBA1B	IC50	'='	19300	nM
P07437	BXGT006624	Tubulin beta chain	reviewed	Cellular structure	TUBB	IC50	'='	19300	nM
Q3ZCM7	BXGT014551	Tubulin beta-8 chain	reviewed	-	TUBB8	IC50	'='	19300	nM
P04350	BXGT006193	Tubulin beta-4A chain	reviewed	Cellular structure	TUBB4A	IC50	'='	19300	nM
Q71U36	BXGT016705	Tubulin alpha-1A chain	reviewed	Cellular structure	TUBA1A	IC50	'='	19300	nM
Q13509	BXGT013366	Tubulin beta-3 chain	reviewed	Cellular structure	TUBB3	IC50	'='	19300	nM
P68366	BXGT011595	Tubulin alpha-4A chain	reviewed	Cellular structure	TUBA4A	IC50	'='	19300	nM
P0DPH7	BXGT007527	Tubulin alpha-3C chain	reviewed	-	TUBA3C	IC50	'='	19300	nM
Q9H4B7	BXGT020475	Tubulin beta-1 chain	reviewed	Cellular structure	TUBB1	IC50	'='	19300	nM
P68371	BXGT011597	Tubulin beta-4B chain	reviewed	Cellular structure	TUBB4B	IC50	'='	19300	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01021	Pinus koraiensis	Pinus koraiensis	Medicinal Plant
BXGF01338	Amsinckia menziesii	Amsinckia menziesii	Others
BXGF01798	Melaleuca uncinata	Melaleuca uncinata	Others
BXGF01833	Hakea saligna	Hakea saligna	Others
BXGF02553	Avrainvillea nigricans	Avrainvillea nigricans	Others
BXGF02639	Rhododendron ferrugineum	Rhododendron ferrugineum	Human Edible Plant
BXGF02713	Drypetes roxburghii	Drypetes roxburghii	Medicinal Plant
BXGF02825	Buddleja variabilis	Buddleja variabilis	Others
BXGF02937	Senecio scandens	Senecio scandens	Medicinal Plant
BXGF03001	Vallaris solanacea	Vallaris solanacea	Medicinal Plant
BXGF03065	Mentha pulegiformis	Mentha pulegiformis	Others
BXGF03096	Salvia nubicola	Salvia nubicola	Human Edible Plant
BXGF03125	Grindelia nana	Grindelia nana	Others
BXGF03170	Haloxylon salicornicum	Haloxylon salicornicum	Medicinal Plant
BXGF03229	Leucanthemum maximum	Leucanthemum maximum	Others
BXGF03249	Vitex trifolia	Vitex trifolia	Medicinal Plant
BXGF03281	Calea megacephala	Calea megacephala	Others
BXGF03323	Abies nobilis	Abies nobilis	Others
BXGF03345	Persea indica	Persea indica	Medicinal Plant
BXGF03369	Corydalis cornuta	Corydalis cornuta	Others
BXGF03401	Disepalum plagioneurum	Disepalum plagioneurum	Others
BXGF03418	Piper aequale	Piper aequale	Medicinal Plant
BXGF03430	Alkanna hirsutissima	Alkanna hirsutissima	Others
BXGF03448	Pinus picea	Pinus picea	Others
BXGF03466	Picris radicata	Picris radicata	Others
BXGF03525	Acrocomia sclerocarpa	Acrocomia sclerocarpa	Others
BXGF03540	Eremophila serrulata	Eremophila serrulata	Others
BXGF03550	Rodgersia podophylla	Rodgersia podophylla	Medicinal Plant
BXGF03566	Delphinium campylocentrum	Delphinium campylocentrum	Others
BXGF03574	Cordyline indivisa	Cordyline indivisa	Medicinal Plant
BXGF03588	Primula hirsuta	Primula hirsuta	Others
BXGF03604	Jasminum grandiflorum	Jasminum grandiflorum	Medicinal Plant
BXGF03611	Viscum coloratum	Viscum coloratum	Medicinal Plant
BXGF05306	Tanacetum cinerariifolium	Tanacetum cinerariifolium	Medicinal Plant
BXGF05563	Phegopteris bukoensis	Phegopteris bukoensis	Others
BXGF05921	Scapania nemorea	Scapania nemorea	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}