Showing entry for Guvacine Hydrochloride


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0016973
Compound NameGuvacine Hydrochloride
Structure
FormulaC6H9NO2.ClH
InchiKeyFGNUNVVTHHKDAM-UHFFFAOYSA-N
SMILESOC(=O)C1=CCCNC1.Cl
InchiInChI=1S/C6H9NO2.ClH/c8-6(9)5-2-1-3-7-4-5;/h2,7H,1,3-4H2,(H,8,9);1H
IUPAC1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydrochloride
Molecular Weight127.06
Pubchem Id11957555
Chembl IdCHEMBL1256362
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1256362
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 115 %
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 89125 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 0 nM
P24387 BXGT008966 Corticotropin-releasing factor-binding protein reviewed Signaling CRHBP EC50 '>' 53000 nM
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 reviewed G-protein coupled receptor CRHR2 EC50 '>' 53000 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 50 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 7943 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 7943 nM
P24387 BXGT008966 Corticotropin-releasing factor-binding protein reviewed Signaling CRHBP IC50 '>' 47100 nM
Q13324 BXGT013340 Corticotropin-releasing factor receptor 2 reviewed G-protein coupled receptor CRHR2 IC50 '>' 47100 nM
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 56234 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 39 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 108 %
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 6309 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF05157 Garcinia morella Garcinia morella Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease