Showing entry for D-Histidine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0023718
Compound NameD-Histidine
Structure
FormulaC6H9N3O2
InchiKeyHNDVDQJCIGZPNO-RXMQYKEDSA-N
SMILESN[C@@H](C(=O)O)Cc1cnc[nH]1
InchiInChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m1/s1
IUPAC(2R)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
Molecular Weight155.07
Pubchem Id71083
Chembl IdCHEMBL104875
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL104875
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ka '=' 43 uM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Kcat '=' 9 10'5/s
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 KA '=' 0 uM
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 KA '=' 1 uM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Kcat '=' 2 10'6/s
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 KA '=' 12 uM
P53615 BXGT011003 Carbonic anhydrase reviewed - NCE103 Ka '=' 85 uM
Q50565 BXGT014936 Carbonic anhydrase unreviewed - MTH_1582 Ka '=' 57 uM
Q6FTL6 BXGT016286 Carbonic anhydrase unreviewed - NCE103 Ka '=' 21 uM
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B KA '=' 4 uM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 14125 nM
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ka '=' 12 uM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 KA '=' 24 uM
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Kcat '=' 3 10'6/s
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 KA '=' 0 uM
Q3I4V7 BXGT014421 Carbonic anhydrase unreviewed - CAN2 KA '=' 47 uM
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ka '=' 13 uM
Q9D6N1 BXGT020260 Carbonic anhydrase 13 reviewed - Ca13 KA '=' 0 uM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 39810 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 39810 nM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A KA '=' 0 uM
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 Kcat '=' 15 10'5/s
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 KA '=' 2 uM
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Kcat '=' 16 10'4/s
P40881 BXGT010205 Carbonic anhydrase reviewed - KA '=' 46 uM
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 KA '=' 14 uM
Q5AJ71 BXGT015288 Carbonic anhydrase reviewed - NCE103 KA '=' 19 uM
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Inhibition '=' 33 %
Q4CVY4 BXGT026093 Carbonic anhydrase-like protein, putative unreviewed - Tc00.1047053509597.20 KA '=' 7 uM
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 Activity '=' 78 %
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 reviewed Transporter SLC7A5 IC50 '=' 460000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00186 Fenugreek Trigonella foenum-graecum Herbs and Spices
BXGF01762 Persea kusanoi Persea kusanoi Others
BXGF03500 Croton megistocarpus Croton megistocarpus Others
BXGF05258 Geranium sibiricum Geranium sibiricum Medicinal Plant
BXGF05301 Baphicacanthus cusia Baphicacanthus cusia Medicinal Plant
BXGF05303 Lagerstroemia indica Lagerstroemia indica Medicinal Plant
BXGF05878 Senecio isatideus Senecio isatideus Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease