acompound

Showing entry for Licarin A

General Compound Information
BXGC Id	BXGC0024489
Compound Name	Licarin A
Structure
Formula	C20H22O4
InchiKey	ITDOFWOJEDZPCF-FNINDUDTSA-N
SMILES	C/C=C/c1cc2c(c(c1)OC)O[C@@H]([C@H]2C)c1ccc(c(c1)OC)O
Inchi	InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m0/s1
IUPAC	2-methoxy-4-[(2S,3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol
Molecular Weight	326.15
Pubchem Id	5281836
Chembl Id	CHEMBL463526

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50303149

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006400	Prostaglandin G/H synthase 1	reviewed		PTGS1	-	312000	-	-
reviewed	BXGT011858	Prostaglandin G/H synthase 2	reviewed		PTGS2	-	32100	-	-

CHEMBL

CHEMBL463526

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	-	KDM4A	Potency	-	50118	nM
P62575	BXGT011435	Sialidase A	reviewed	-	nanA	Inhibition	-	-	-
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	517	nM
P79208	BXGT011858	Prostaglandin G/H synthase 2	reviewed	-	PTGS2	IC50	'='	32100	nM
P00489	BXGT005553	Glycogen phosphorylase, muscle form	reviewed	-	PYGM	Inhibition	'='	8	%
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	IC50	'='	312000	nM
Q8WZA2	BXGT019025	Rap guanine nucleotide exchange factor 4	reviewed	Enzyme modulator	RAPGEF4	Potency	-	39810	nM
P39748	BXGT010134	Flap endonuclease 1	reviewed	Enzyme	FEN1	Potency	-	79432	nM
P00489	BXGT005553	Glycogen phosphorylase, muscle form	reviewed	-	PYGM	IC50	-	-	-
O95149	BXGT005350	Snurportin-1	reviewed	-	SNUPN	Potency	-	8199	nM
Q14974	BXGT013516	Importin subunit beta-1	reviewed	Transporter	KPNB1	Potency	-	8199	nM
P62826	BXGT011463	GTP-binding nuclear protein Ran	reviewed	Enzyme modulator	RAN	Potency	-	8199	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	25929	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	1158	nM
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	reviewed	Transcription factor	SMAD3	Potency	-	35481	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	18356	nM
P62575	BXGT011435	Sialidase A	reviewed	-	nanA	IC50	'='	7900	nM
P62575	BXGT011435	Sialidase A	reviewed	-	nanA	Ki	'='	9400	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	7943	nM
P37840	BXGT010015	Alpha-synuclein	reviewed	Transporter	SNCA	Potency	-	7943	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00118	Nutmeg	Myristica fragrans	Herbs and Spices
BXGF01709	Hyptis tomentosa	Hyptis tomentosa	Medicinal Plant
BXGF02562	Cephalonoplos segetum	Cephalonoplos segetum	Human Edible Plant
BXGF03056	Saururus chinensis	Saururus chinensis	Medicinal Plant
BXGF04646	Lens phaseoloides	Lens phaseoloides	Others
BXGF05294	Ipomoea cristulata	Ipomoea cristulata	Others
BXGF05363	Lophozonia menziesii	Lophozonia menziesii	Others
BXGF05443	Rhodotypos scandens	Rhodotypos scandens	Others
BXGF05527	Pancratium trianthum	Pancratium trianthum	Human Edible Plant
BXGF05589	Piper pedicellosum	Piper pedicellosum	Medicinal Plant
BXGF05808	Xanthostemon oppositifolius	Xanthostemon oppositifolius	Others
BXGF05836	Esenbeckia nesiotica	Esenbeckia nesiotica	Others
BXGF05999	Catalpa bignonioides	Catalpa bignonioides	Medicinal Plant
BXGF06045	Helipterum tenellum	Helipterum tenellum	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}