Showing entry for Vitamin K 1


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0024665
Compound NameVitamin K 1
Structure
FormulaC31H46O2
InchiKeyMBWXNTAXLNYFJB-NKFFZRIASA-N
SMILESC[C@H](CCC[C@@H](CCCC(C)C)C)CCC/C(=C/CC1=C(C)C(=O)c2c(C1=O)cccc2)/C
InchiInChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
IUPAC2-methyl-3-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione
Molecular Weight450.35
Pubchem Id5284607
Chembl IdCHEMBL1550
Targets of Information Source
DrugBank DB01022
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase reviewed - GGCX approved; investigational inducer
P02818 BXGT005969 Osteocalcin reviewed - BGLAP approved; investigational agonist
PDB PQN
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P0A405 BXGT007024 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
P0A407 BXGT007025 Photosystem I P700 chlorophyll a apoprotein A2 reviewed psaB - - - - -
P05310 BXGT006346 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
P05311 BXGT006347 Photosystem I P700 chlorophyll a apoprotein A2 reviewed psaB - - - - -
P29254 BXGT009324 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
P29255 BXGT009325 Photosystem I P700 chlorophyll a apoprotein A2 reviewed psaB - - - - -
A0A0F6NGI2 BXGT000184 Photosystem I P700 chlorophyll a apoprotein A2 unreviewed psaB - - - - -
Q85FY7 BXGT017578 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
Q85FY6 BXGT017577 Photosystem I P700 chlorophyll a apoprotein A2 reviewed psaB - - - - -
P04966 BXGT006291 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
A0A059Q6U2 BXGT000015 Photosystem I P700 chlorophyll a apoprotein A2 unreviewed psaB - - - - -
A0A4V8GZZ2 BXGT024313 Photosystem I P700 chlorophyll a apoprotein A1 unreviewed - - - - -
A0A4V8H003 BXGT024314 Photosystem I unreviewed - - - - -
P12154 BXGT024331 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
P09144 BXGT024332 Photosystem I P700 chlorophyll a apoprotein A2 reviewed psaB - - - - -
P58576 BXGT024586 Photosystem I P700 chlorophyll a apoprotein A1 reviewed psaA - - - - -
P58565 BXGT024587 Photosystem I P700 chlorophyll a apoprotein A2 1 reviewed psaB1 - - - - -
Q8DMR6 BXGT024752 NAD(P)H-quinone oxidoreductase subunit 2 reviewed ndhB - - - - -
G6FME9 BXGT025233 Photosystem I P700 chlorophyll a apoprotein A1 unreviewed psaA - - - - -
G6FMF0 BXGT025234 Photosystem I P700 chlorophyll a apoprotein A2 unreviewed psaB - - - - -
D0FXV2 BXGT025354 Photosystem I P700 chlorophyll a apoprotein A1 unreviewed psaA - - - - -
D0FXZ0 BXGT025355 Photosystem I P700 chlorophyll a apoprotein A2 unreviewed psaB - - - - -
A0A2S6VGM5 BXGT025383 Photosystem I P700 chlorophyll a apoprotein A1 unreviewed psaA - - - - -
A0A2S6VGS2 BXGT025384 Photosystem I P700 chlorophyll a apoprotein A2 unreviewed psaB - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1550
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 reviewed Enzyme modulator RAPGEF3 Potency - 56234 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 100000 nM
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 Activity - - -
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 reviewed - IDO1 Activity - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 50118 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 29092 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00200 Mung bean Vigna radiata Pulses
BXGF01580 Changium smyrnioides Changium smyrnioides Medicinal Plant
BXGF05853 Cannabis sativa Cannabis sativa Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease