Showing entry for Indoleamine 2,3-dioxygenase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008065
Protein NameIndoleamine 2,3-dioxygenase 1
Uniport IdP14902
GeneIDO1
Gene Id3620
DomainIDO
Pfam PF01231  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05143 African trypanosomiasis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034354 'de novo' NAD biosynthetic process from tryptophan
Biological Process GO:0002534 cytokine production involved in inflammatory response
Biological Process GO:0007565 female pregnancy
Biological Process GO:0002376 immune system process
Biological Process GO:0034276 kynurenic acid biosynthetic process
Biological Process GO:0033555 multicellular organismal response to stress
Biological Process GO:0032693 negative regulation of interleukin-10 production
Biological Process GO:0070233 negative regulation of T cell apoptotic process
Biological Process GO:0042130 negative regulation of T cell proliferation
Biological Process GO:0002678 positive regulation of chronic inflammatory response
Biological Process GO:0032735 positive regulation of interleukin-12 production
Biological Process GO:0070234 positive regulation of T cell apoptotic process
Biological Process GO:0002666 positive regulation of T cell tolerance induction
Biological Process GO:0002830 positive regulation of type 2 immune response
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0036269 swimming behavior
Biological Process GO:0006569 tryptophan catabolic process
Biological Process GO:0019441 tryptophan catabolic process to kynurenine
molecular function GO:0009055 electron transfer activity
molecular function GO:0020037 heme binding
molecular function GO:0033754 indoleamine 2,3-dioxygenase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004833 tryptophan 2,3-dioxygenase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030485 smooth muscle contractile fiber
cellular component GO:0032421 stereocilium bundle
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71240 Tryptophan catabolism
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004030 BXGD000246 Aspergillosis Infections
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006060 BXGD000364 Boutonneuse Fever Infections
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006852 BXGD000414 Candidiasis of vagina Female Urogenital Diseases and Pregnancy Complications; Infections
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007118 BXGD000434 Carcinoma, Basosquamous Neoplasms
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0008354 BXGD000533 Cholera Infections
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0013371 BXGD000823 Shigella Infections Digestive System Diseases; Infections
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023646 BXGD001690 Lichen Planus Skin and Connective Tissue Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023892 BXGD001715 Biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024534 BXGD001784 Malaria, Cerebral Infections; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025007 BXGD001821 Measles Infections
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026946 BXGD001951 Mycoses Infections
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027643 BXGD002007 Neoplasm Recurrence, Local Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033680 BXGD002414 Protein-Losing Enteropathies Digestive System Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040558 BXGD002873 Toxoplasmosis Infections
C0041182 BXGD002896 Trophoblastic Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042769 BXGD002999 Virus Diseases Infections
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0043094 BXGD003026 Weight Gain Pathological Conditions, Signs and Symptoms
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086543 BXGD003294 Cataract Eye Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153446 BXGD003646 Malignant neoplasm of anus Digestive System Diseases; Neoplasms
C0153579 BXGD003668 Malignant neoplasm of fallopian tube Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162565 BXGD003957 Acute intermittent porphyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0175697 BXGD004004 Van der Woude syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0178417 BXGD004025 Anhedonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205734 BXGD004115 Diabetes, Autoimmune Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0205969 BXGD004143 Thymic Carcinoma Neoplasms; Hemic and Lymphatic Diseases
C0206693 BXGD004244 Medullary carcinoma Neoplasms
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220621 BXGD004300 Childhood Acute Myeloid Leukemia Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0221757 BXGD004472 alpha 1-Antitrypsin Deficiency Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238122 BXGD004882 Fallopian Tube Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238650 BXGD004950 ankle arthritis Musculoskeletal Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0241910 BXGD005123 Autoimmune Chronic Hepatitis Digestive System Diseases; Immune System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242584 BXGD005179 Autoimmune thrombocytopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0243010 BXGD005209 Viral Encephalitis Infections; Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0243038 BXGD005211 Carcinoma, Lewis Lung Neoplasms
C0268398 BXGD005933 Familial lichen amyloidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0270715 BXGD006089 Degenerative Diseases, Central Nervous System Nervous System Diseases
C0272286 BXGD006337 Thrombocytopenia due to platelet alloimmunization Hemic and Lymphatic Diseases
C0276138 BXGD006403 Viral myocarditis Infections; Cardiovascular Diseases
C0276289 BXGD006418 Zika Virus Infection Infections
C0276665 BXGD006441 Pulmonary paracoccidioidomycosis Infections
C0278488 BXGD006515 Carcinoma breast stage IV
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278882 BXGD006613 Stage III Cutaneous Melanoma AJCC v6
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279637 BXGD006665 Anal carcinoma Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280218 BXGD006721 stage, bladder cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349534 BXGD007919 Carcinoma of anal margin Digestive System Diseases; Neoplasms
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431129 BXGD008665 Adamantinous Craniopharyngioma Neoplasms
C0438696 BXGD008805 Suicidal Behavior and Behavior Mechanisms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494791 BXGD009034 Hepatic fibrosis and cirrhosis Digestive System Diseases
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0581391 BXGD009570 Chronic depression Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700345 BXGD009886 Candidiasis, Vulvovaginal Female Urogenital Diseases and Pregnancy Complications; Infections
C0743178 BXGD010077 Intractable diarrhea Pathological Conditions, Signs and Symptoms
C0751733 BXGD010569 Degenerative Diseases, Spinal Cord Nervous System Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0860580 BXGD011232 Medullary carcinoma of breast
C0871388 BXGD011314 social stress Behavior and Behavior Mechanisms
C0877008 BXGD011325 Enzyme inhibition disorder
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936250 BXGD011481 Eczema Herpeticum Infections; Skin and Connective Tissue Diseases
C0948192 BXGD011514 Primary infection NOS
C1096903 BXGD011645 Sialic Acid Storage Disease, Finnish Type (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1112734 BXGD011683 Gastric infection
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1262091 BXGD011867 Lymphocytic infiltration
C1266050 BXGD011945 Poorly Differentiated Thyroid Carcinoma Neoplasms; Endocrine System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1279945 BXGD012124 Acute interstitial pneumonia Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1412036 BXGD013053 Anal squamous cell carcinoma Digestive System Diseases; Neoplasms
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1504431 BXGD013144 Idiopathic pneumonia syndrome Infections; Respiratory Tract Diseases
C1519214 BXGD013233 Glioblastoma, IDH-Mutant Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1609538 BXGD013444 Latent Tuberculosis Infections
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1739135 BXGD013733 Progression of prostate cancer
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1840264 BXGD014439 IMMUNE SUPPRESSION
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1852242 BXGD015266 Nonarteritic anterior ischemic optic neuropathy (NAION)
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2985280 BXGD018223 Blood Protein Measurement
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3714514 BXGD019409 Infection Infections
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3887639 BXGD019907 Autoimmune gastritis Digestive System Diseases
C3888523 BXGD019977 Autoimmune uveitis
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4085243 BXGD022112 MEND SYNDROME
C4087504 BXGD022156 Peritoneal dissemination
C4288754 BXGD022484 Metastatic urothelial carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4290046 BXGD022507 trachomatis
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4523846 BXGD023079 MSI-high
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721555 BXGD023755 Autoimmune hepatitis Digestive System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4725091 BXGD023828 metastatic intraocular melanoma Neoplasms; Eye Diseases
C4727838 BXGD023874 Advanced Melanoma
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0000279 L-Alanine 89.09
BXGC0000436 Glycerol 92.09
BXGC0000528 Salicylic acid 138.12
BXGC0000548 Tryptamine 160.22
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001623 L-Tryptophan 204.23
BXGC0001691 Questiomycin A 212.2
BXGC0001725 2(3H)-Benzothiazolethione 167.25
BXGC0001991 Juglone 174.15
BXGC0002052 Aesculetin 178.14
BXGC0002591 Potassium 39.1
BXGC0002978 1,2,4-Trihydroxybenzene 126.11
BXGC0003005 3-Phenylpyridine 155.2
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0003502 Phenylhydrazine 108.14
BXGC0003610 5-Hydroxy-L-tryptophan 220.22
BXGC0003705 Chloride 35.45
BXGC0003751 Cyanide 26.02
BXGC0003852 Nigrin B 506.47
BXGC0004115 Norharman 168.19
BXGC0004560 Benzoic acid 122.12
BXGC0004569 Benzophenone 182.22
BXGC0004650 4-Methyl-1,2-benzenediol 124.14
BXGC0004708 4-Hydroxybenzaldehyde 122.12
BXGC0004999 Benzothiazole 135.19
BXGC0005000 2-Benzoxazolone 135.12
BXGC0005006 Chromone 146.14
BXGC0005046 Tryptophol 161.2
BXGC0005060 2-Methylbenzothiazole 149.21
BXGC0005169 4-Phenylpyridine 155.2
BXGC0005345 Brassinin 236.36
BXGC0006153 Harmol 198.22
BXGC0007629 Benzaldehyde 106.12
BXGC0008676 Haem 616.49
BXGC0011718 Brassitin 220.29
BXGC0014059 2-Methoxy-1,4-Naphthoquinone 188.05
BXGC0014164 9-fluorenone 180.06
BXGC0017450 4-hydroxymandelic acid 168.04
BXGC0019164 Raloxifene 473.17
BXGC0020024 Lawsone 174.03
BXGC0020680 Mandelic Acid 152.05
BXGC0024665 Vitamin K 1 450.35
BXGC0024729 Mercaptopurine 152.02
BXGC0024988 Nifedipine 346.12
BXGC0025206 Alpha-Lapachone 242.09
BXGC0027259 Tryptanthrin 248.06
BXGC0028001 Beta-Lapachone 242.09
BXGC0029047 9H-Fluoren-9-Ol 182.07
BXGC0030928 Avicennol 342.15
BXGC0031072 Naphthalene-1,4-Diol 160.05
BXGC0038719 1,6-Dimethyl-1,2-Dihydronaphtho[1,2-G][1]Benzofuran-10,11-Dione 278.09
BXGC0039019 Harmol 198.08
BXGC0039085 Dehydro-Alpha-Lapachone 240.08
BXGC0040150 Cannabidiol 314.22
BXGC0041312 dehydrotanshinone II A 292.11
BXGC0042127 Oxyquinoline 145.05
BXGC0044200 Menadione 172.05
BXGC0044387 Benzenemethanethiol 124.03
BXGC0046032 9H-Carbazol-4-Ol 183.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein