Showing entry for N,N-Dimethyldodecan-1-Amine Oxide


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0042373
Compound NameN,N-Dimethyldodecan-1-Amine Oxide
Structure
FormulaC14H31NO
InchiKeySYELZBGXAIXKHU-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCN(=O)(C)C
InchiInChI=1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3
IUPACN,N-dimethyldodecan-1-amine oxide
Molecular Weight229.24
Pubchem Id15433
Chembl IdCHEMBL1233973
Targets of Information Source
DrugBank DB04147
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P13036 BXGT007875 Fe(3+) dicitrate transport protein FecA reviewed - fecA experimental -
P10384 BXGT007563 Long-chain fatty acid transport protein reviewed - fadL experimental -
P37001 BXGT009951 Lipid A palmitoyltransferase PagP reviewed - pagP experimental -
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed - MAOB experimental ligand
P0AGG2 BXGT007376 Acyl-CoA thioesterase 2 reviewed - tesB experimental -
P0C0Y8 BXGT007395 Reaction center protein L chain reviewed - pufL experimental -
P0C0Y9 BXGT007396 Reaction center protein M chain reviewed - pufM experimental -
P0C0Y7 BXGT007394 Reaction center protein H chain reviewed - puhA experimental -
P98002 BXGT012223 Cytochrome c oxidase subunit 1-beta reviewed - ctaDII experimental -
P08306 BXGT006761 Cytochrome c oxidase subunit 2 reviewed - ctaC experimental -
P01593 BXGT005775 Immunoglobulin kappa variable 1D-33 reviewed - IGKV1D-33 experimental -
P01764 BXGT005784 Immunoglobulin heavy variable 3-23 reviewed - IGHV3-23 experimental -
P07173 BXGT006562 Photosynthetic reaction center cytochrome c subunit reviewed - pufC experimental -
P06008 BXGT006405 Reaction center protein H chain reviewed - puhA experimental -
P06009 BXGT006406 Reaction center protein L chain reviewed - pufL experimental -
P06010 BXGT006407 Reaction center protein M chain reviewed - pufM experimental -
Q93RD8 BXGT019520 H subunit of photosynthetic reaction center complex (Fragment) unreviewed - puhA experimental -
P60981 BXGT011344 Destrin reviewed - DSTN experimental -
P08100 BXGT006725 Rhodopsin reviewed G-protein coupled receptor RHO experimental -
P0C0X8 BXGT007393 Cytochrome c2 reviewed - cycA experimental -
Q14494 BXGT013474 Endoplasmic reticulum membrane sensor NFE2L1 reviewed Enzyme NFE2L1 experimental -
P33247 BXGT009706 Squalene--hopene cyclase reviewed - shc experimental -
P06129 BXGT006413 Vitamin B12 transporter BtuB reviewed - btuB experimental -
P00646 BXGT005606 Colicin-E3 reviewed - ceaC experimental -
P42512 BXGT010311 Fe(3+)-pyochelin receptor reviewed - fptA experimental -
P02689 BXGT005919 Myelin P2 protein reviewed - PMP2 experimental -
P0A915 BXGT007165 Outer membrane protein W reviewed - ompW experimental -
P26789 BXGT009136 Light-harvesting protein B-800/850 alpha chain reviewed - - experimental -
P26790 BXGT009137 Light-harvesting protein B-800/850 beta chain reviewed - - experimental -
P02929 BXGT005991 Protein TonB reviewed - tonB experimental -
P17315 BXGT008301 Colicin I receptor reviewed - cirA experimental -
P06716 BXGT006481 Colicin-Ia reviewed - cia experimental -
P23528 BXGT008879 Cofilin-1 reviewed - CFL1 experimental -
P09391 BXGT006885 Rhomboid protease GlpG reviewed - glpG experimental -
P76045 BXGT011769 Outer membrane porin G reviewed - ompG experimental -
P07110 BXGT006552 Outer membrane usher protein PapC reviewed - papC experimental -
P69856 BXGT011645 Probable N-acetylneuraminic acid outer membrane channel protein NanC reviewed - nanC experimental -
Q3J170 BXGT014436 Reaction center protein H chain reviewed - puhA experimental -
Q3J1A5 BXGT014437 Reaction center protein L chain reviewed - pufL experimental -
Q3J1A6 BXGT014438 Reaction center protein M chain reviewed - pufM experimental -
Q5RT80 BXGT015648 Outer membrane protein II (Fragment) unreviewed - porB experimental -
Q98GN8 BXGT019897 Cyclic nucleotide-gated potassium channel mll3241 reviewed - mll3241 experimental -
P69681 BXGT011637 Ammonia channel reviewed - amtB experimental -
A0A0H2WWQ9 BXGT000310 Penicillin-binding protein 2 unreviewed - pbp2 experimental -
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial reviewed Enzyme DHODH experimental -
Q46704 BXGT014650 TraO protein unreviewed - traO experimental -
Q46705 BXGT014651 TraF protein unreviewed - traF experimental -
Q46702 BXGT014649 TraN protein unreviewed - traN experimental -
Q4KH25 BXGT014847 Outer membrane porin, OprD family unreviewed - PFL_1329 experimental -
PDB LDA
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P0C0Y9 BXGT007396 Reaction center protein M chain reviewed pufM - - - - -
P98002 BXGT012223 Cytochrome c oxidase subunit 1-beta reviewed ctaDII - - - - -
P08306 BXGT006761 Cytochrome c oxidase subunit 2 reviewed ctaC - - - - -
P0AGG2 BXGT007376 Acyl-CoA thioesterase 2 reviewed tesB - - - - -
P06008 BXGT006405 Reaction center protein H chain reviewed puhA - - - - -
P06009 BXGT006406 Reaction center protein L chain reviewed pufL - - - - -
P06010 BXGT006407 Reaction center protein M chain reviewed pufM - - - - -
P0C0Y7 BXGT007394 Reaction center protein H chain reviewed puhA - - - - -
P0C0Y8 BXGT007395 Reaction center protein L chain reviewed pufL - - - - -
Q39250 BXGT014374 Actin-depolymerizing factor 1 reviewed ADF1 - - - - -
P02699 BXGT005925 Rhodopsin reviewed RHO - - - - -
P13036 BXGT007875 Fe(3+) dicitrate transport protein FecA reviewed fecA - - - - -
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed MAOB - - - - -
P34707 BXGT009762 Protein skinhead-1 reviewed skn-1 - - - - -
P33247 BXGT009706 Squalene--hopene cyclase reviewed shc - - - - -
P10384 BXGT007563 Long-chain fatty acid transport protein reviewed fadL - - - - -
P37001 BXGT009951 Lipid A palmitoyltransferase PagP reviewed pagP - - - - -
P06129 BXGT006413 Vitamin B12 transporter BtuB reviewed btuB - - - - -
P42512 BXGT010311 Fe(3+)-pyochelin receptor reviewed fptA - - - - -
P0C6G6 BXGT007429 Myelin P2 protein reviewed PMP2 - - - - -
P0A915 BXGT007165 Outer membrane protein W reviewed ompW - - - - -
P26789 BXGT009136 Light-harvesting protein B-800/850 alpha chain reviewed - - - - -
P26790 BXGT009137 Light-harvesting protein B-800/850 beta chain reviewed - - - - -
Q7B302 BXGT016920 Photosynthetic reaction center subunit H unreviewed puhA - - - - -
P52754 BXGT010949 Hydrophobin-1 reviewed hfb1 - - - - -
P17315 BXGT008301 Colicin I receptor reviewed cirA - - - - -
P78929 BXGT011853 Cofilin reviewed cof1 - - - - -
P09391 BXGT006885 Rhomboid protease GlpG reviewed glpG - - - - -
P76045 BXGT011769 Outer membrane porin G reviewed ompG - - - - -
P07110 BXGT006552 Outer membrane usher protein PapC reviewed papC - - - - -
P69856 BXGT011645 Probable N-acetylneuraminic acid outer membrane channel protein NanC reviewed nanC - - - - -
Q3J170 BXGT014436 Reaction center protein H chain reviewed puhA - - - - -
Q3J1A6 BXGT014438 Reaction center protein M chain reviewed pufM - - - - -
P71817 BXGT011697 Steroid isomerase, putative unreviewed MT0785 - - - - -
Q5RT80 BXGT015648 Outer membrane protein II unreviewed porB - - - - -
Q98GN8 BXGT019897 Cyclic nucleotide-gated potassium channel mll3241 reviewed mll3241 - - - - -
P69681 BXGT011637 Ammonia channel reviewed amtB - - - - -
Q8KHY3 BXGT018424 Penicillin-binding protein unreviewed pbpB - - - - -
Q08210 BXGT012969 Dihydroorotate dehydrogenase (quinone), mitochondrial reviewed PFF0160c - - - - -
Q46705 BXGT014651 TraF protein unreviewed traF - - - - -
Q4KH25 BXGT014847 Outer membrane porin, OprD family unreviewed PFL_1329 - - - - -
B9W5G6 BXGT002360 DELTA-actitoxin-Afr1a reviewed - - - - -
P37432 BXGT009985 Outer membrane porin F reviewed ompF - - - - -
P07173 BXGT006562 Photosynthetic reaction center cytochrome c subunit reviewed pufC - - - - -
Q5QUJ8 BXGT015641 Sulfate transporter CysZ unreviewed cysZ - - - - -
Q9K0A9 BXGT020861 Transporter unreviewed NMB0705 - - - - -
P18895 BXGT008439 Alginate production protein AlgE reviewed algE - - - - -
Q8AWD0 BXGT017894 Vdac2 protein unreviewed vdac2 - - - - -
Q60932 BXGT016005 Voltage-dependent anion-selective channel protein 1 reviewed Vdac1 - - - - -
P06971 BXGT006528 Ferrichrome outer membrane transporter/phage receptor reviewed fhuA - - - - -
E3U905 BXGT003112 Outer membrane porin protein OmpD unreviewed ompD - - - - -
P07602 BXGT006646 Prosaposin reviewed PSAP - - - - -
P46359 BXGT010514 Pesticin receptor reviewed fyuA - - - - -
F6XHE4 BXGT003301 Uncharacterized protein unreviewed - - - - -
Q4W8A1 BXGT014907 Voltage-sensor containing phosphatase unreviewed Ci-VSP - - - - -
P08563 BXGT006790 Structural polyprotein reviewed - - - - -
Q3J125 BXGT014434 Cellulose synthase catalytic subunit [UDP-forming] unreviewed RSP_0333 - - - - -
Q3J1A5 BXGT014437 Reaction center protein L chain reviewed pufL - - - - -
Q2G506 BXGT014057 ATM1-type heavy metal exporter reviewed atm1 - - - - -
A0A140N9T3 BXGT000658 Phosphatidylglycerophosphatase unreviewed ECBD_2341 - - - - -
Q83SQ0 BXGT017513 LPS-assembly protein LptD reviewed lptD - - - - -
P06609 BXGT006457 Vitamin B12 import system permease protein BtuC reviewed btuC - - - - -
Q6D8U4 BXGT016241 Uncharacterized protein unreviewed ECA0878 - - - - -
P0AEY8 BXGT007336 Multidrug transporter MdfA reviewed mdfA - - - - -
Q8U4M3 BXGT018898 Dolichol monophosphate mannose synthase unreviewed PF0058 - - - - -
P49913 BXGT010761 Cathelicidin antimicrobial peptide reviewed CAMP - - - - -
E3U904 BXGT003111 Porin 1 unreviewed ompC - - - - -
C4IN73 BXGT002466 FapF unreviewed fapF - - - - -
P0C6Q6 BXGT007431 Outer membrane protein U reviewed ompU - - - - -
D2Z0P2 BXGT002871 LH1 alpha polypeptide unreviewed pufA - - - - -
D2Z0P1 BXGT002870 LH1 beta polypeptide unreviewed pufB - - - - -
A8ASG6 BXGT001661 Reaction center protein M chain unreviewed pufM - - - - -
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial reviewed DHODH Enzyme - - - -
O67181 BXGT024813 ABC transporter unreviewed abcT4 - - - - -
O67182 BXGT024814 Transport permease protein unreviewed abcT3 - - - - -
P35672 BXGT025208 Type 3 secretion system secretin reviewed sctC - - - - -
D6QLY1 BXGT025430 OmpK36 unreviewed ompK36 - - - - -
Binding DB 50327308
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010632 Lanosterol synthase reviewed LSS - 2150 - -
reviewed BXGT010632 Lanosterol synthase reviewed LSS - 6310 - -
CHEMBL CHEMBL1233973
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P48449 BXGT010632 Lanosterol synthase reviewed - LSS Inhibition '=' 85 %
P48449 BXGT010632 Lanosterol synthase reviewed - LSS IC50 '=' 6310 nM
P48449 BXGT010632 Lanosterol synthase reviewed - LSS Inhibition '=' 84 %
Q9R1A7 BXGT021413 Nuclear receptor subfamily 1 group I member 2 reviewed - Nr1i2 Potency - 50118 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 44668 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 28183 nM
P48449 BXGT010632 Lanosterol synthase reviewed - LSS IC50 '=' 2150 nM
P48449 BXGT010632 Lanosterol synthase reviewed - LSS Inhibition '=' 100 %
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 34376 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 22387 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 48557 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00125 Rice Oryza sativa Cereals and cereal products
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease