acompound

Showing entry for Calycosin

General Compound Information
BXGC Id	BXGC0051184
Compound Name	Calycosin
Structure
Formula	C16H12O5
InchiKey	ZZAJQOPSWWVMBI-UHFFFAOYSA-N
SMILES	COc1ccc(cc1O)c1coc2c(c1=O)ccc(c2)O
Inchi	InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3
IUPAC	7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Molecular Weight	284.07
Pubchem Id	5280448
Chembl Id	CHEMBL241608

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL241608

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	12990	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	9528	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	9196	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	28183	nM
P06746	BXGT006496	DNA polymerase beta	reviewed	Enzyme	POLB	Potency	'='	25118	nM
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	79432	nM
Q63470	BXGT016073	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	reviewed	-	Dyrk1a	AC50	'='	16138	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	35481	nM
Q62986	BXGT016053	Estrogen receptor beta	reviewed	-	Esr2	Activity	-	-	-
P06211	BXGT006424	Estrogen receptor	reviewed	-	Esr1	Activity	-	-	-
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	50118	nM
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	reviewed	Transporter	NPC1	Potency	'='	5623	nM
P51151	BXGT010837	Ras-related protein Rab-9A	reviewed	-	RAB9A	Potency	'='	5623	nM
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	reviewed	Enzyme	BRCA1	Potency	-	12589	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	28183	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00186	Fenugreek	Trigonella foenum-graecum	Herbs and Spices
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00857	Mitracarpus scaber	Mitracarpus scaber	Others
BXGF00861	Abies pinsapo var. marocana	Abies pinsapo var. marocana	Others
BXGF00939	Triclisia subcordata	Triclisia subcordata	Others
BXGF01026	Aspilia parvifolia	Aspilia parvifolia	Others
BXGF01168	Erysimum leptophyllum	Erysimum leptophyllum	Others
BXGF01251	Psorothamnus arborescens	Psorothamnus arborescens	Others
BXGF01295	Chondrodendron tomentosum	Chondrodendron tomentosum	Medicinal Plant
BXGF01354	Haplophyllum obtusifolium	Haplophyllum obtusifolium	Others
BXGF01373	Myroxylon peruiferum	Myroxylon peruiferum	Others
BXGF01421	Corydalis densiflora	Corydalis densiflora	Others
BXGF01485	Schleichera trijuga	Schleichera trijuga	Medicinal Plant
BXGF01621	Syzygium polycephaloides	Syzygium polycephaloides	Human Edible Plant
BXGF01632	Euphrasia genargentea	Euphrasia genargentea	Others
BXGF01640	Craibiodendron yunnanense	Craibiodendron yunnanense	Others
BXGF01661	Napoleonaea vogelii	Napoleonaea vogelii	Human Edible Plant
BXGF01762	Persea kusanoi	Persea kusanoi	Others
BXGF01768	Dalbergia parviflora	Dalbergia parviflora	Medicinal Plant
BXGF01892	Xanthorhiza simplicissima	Xanthorhiza simplicissima	Medicinal Plant
BXGF01986	Mabea fistulifera	Mabea fistulifera	Others
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02067	Barringtonia acutangula	Barringtonia acutangula	Medicinal Plant
BXGF02103	Astragalus mongholicus	Astragalus mongholicus	Medicinal Plant
BXGF02109	Embelia ribes	Embelia ribes	Medicinal Plant
BXGF02131	Glycyrrhiza	Glycyrrhiza	Medicinal Plant
BXGF02186	Astragalus adsurgens	Astragalus adsurgens	Others
BXGF02202	Piper regnellii	Piper regnellii	Medicinal Plant
BXGF02211	Desmodium canadense	Desmodium canadense	Others
BXGF02287	Gymnocalycium schickendantzii	Gymnocalycium schickendantzii	Others
BXGF02381	Glycyrrhiza inflata	Glycyrrhiza inflata	Medicinal Plant
BXGF02445	Onopordum acanthium	Onopordum acanthium	Medicinal Plant
BXGF02500	Pancratium sickenbergeri	Pancratium sickenbergeri	Others
BXGF02523	Andira inermis	Andira inermis	Medicinal Plant
BXGF02573	Centaurea maculosa	Centaurea maculosa	Others
BXGF02635	Ephedra sinica	Ephedra sinica	Medicinal Plant
BXGF02695	Plathymenia reticulata	Plathymenia reticulata	Others
BXGF02729	Asimina parviflora	Asimina parviflora	Medicinal Plant
BXGF02774	Pteridium esculentum	Pteridium esculentum	Medicinal Plant
BXGF02813	Esenbeckia leiocarpa	Esenbeckia leiocarpa	Others
BXGF02852	Sophora flavescens	Sophora flavescens	Medicinal Plant
BXGF02929	Hypericum styphelioides	Hypericum styphelioides	Others
BXGF02946	Artemisia anomala	Artemisia anomala	Medicinal Plant
BXGF02963	Jasminum sambac	Jasminum sambac	Medicinal Plant
BXGF02973	Vellozia nanuzae	Vellozia nanuzae	Others
BXGF02992	Baccharis neglecta	Baccharis neglecta	Others
BXGF03012	Atraphaxis spinosa	Atraphaxis spinosa	Medicinal Plant
BXGF03027	Embelia schimperi	Embelia schimperi	Medicinal Plant
BXGF03070	Callerya cinerea	Callerya cinerea	Human Edible Plant
BXGF03087	Epilobium hirsutum	Epilobium hirsutum	Medicinal Plant
BXGF03100	Astragalus complanatus	Astragalus complanatus	Medicinal Plant
BXGF03106	Lythrum salicaria	Lythrum salicaria	Medicinal Plant
BXGF03113	Simarouba glauca	Simarouba glauca	Medicinal Plant
BXGF03126	Erythrina melanacantha	Erythrina melanacantha	Medicinal Plant
BXGF03151	Monsonia senegalensis	Monsonia senegalensis	Human Edible Plant
BXGF03157	Clerodendrum bungei	Clerodendrum bungei	Medicinal Plant
BXGF03186	Lemaireocereus longispinus	Lemaireocereus longispinus	Others
BXGF03197	Eria anomala	Eria anomala	Others
BXGF03208	Embelia parviflora	Embelia parviflora	Medicinal Plant
BXGF03231	Dactylorhiza viridis	Dactylorhiza viridis	Others
BXGF03250	Euphorbia nematocypha	Euphorbia nematocypha	Medicinal Plant
BXGF03271	Pterolobium hexapetalum	Pterolobium hexapetalum	Medicinal Plant
BXGF03279	Abelia chinensis	Abelia chinensis	Unclassified
BXGF03297	Diospyros assimilis	Diospyros assimilis	Medicinal Plant
BXGF03310	Faramea salicifolia	Faramea salicifolia	Others
BXGF03397	Trifolium pratense	Trifolium pratense	Medicinal Plant
BXGF03500	Croton megistocarpus	Croton megistocarpus	Others
BXGF03564	Vernonia fagifolia	Vernonia fagifolia	Others
BXGF03570	Cordia leucocephala	Cordia leucocephala	Others
BXGF03813	Diplopterygium glaucum	Diplopterygium glaucum	Others
BXGF03859	Sophora moorcroftiana	Sophora moorcroftiana	Medicinal Plant
BXGF03901	Astragalus membranaceus	Astragalus membranaceus	Medicinal Plant
BXGF03908	Hedysarum multijugum maxim	Hedysarum multijugum maxim	Others
BXGF03995	Sophora secundiflora	Sophora secundiflora	Human Edible Plant
BXGF04062	Spatholobus suberectus	Spatholobus suberectus	Medicinal Plant
BXGF04150	Erycibe expansa	Erycibe expansa	Medicinal Plant
BXGF04263	Glycine soja	Glycine soja	Medicinal Plant
BXGF04292	Bowdichia virgilioides	Bowdichia virgilioides	Medicinal Plant
BXGF04296	Maytenus chuchuhuasha	Maytenus chuchuhuasha	Others
BXGF04301	Dorstenia dinklagei	Dorstenia dinklagei	Others
BXGF04328	Croton zehntneri	Croton zehntneri	Others
BXGF04458	Oxytropis falcata	Oxytropis falcata	Others
BXGF04584	Helichrysum tenuifolium	Helichrysum tenuifolium	Others
BXGF04627	Bowdichia nitida	Bowdichia nitida	Others
BXGF04772	Sapium haematospermum	Sapium haematospermum	Medicinal Plant
BXGF04789	Khaya grandifoliola	Khaya grandifoliola	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF04872	Glycyrrhiza glabra	Glycyrrhiza glabra	Medicinal Plant
BXGF05009	Solanum lanceolatum	Solanum lanceolatum	Medicinal Plant
BXGF05010	Morella rubra	Morella rubra	0
BXGF05067	Bryonia alba	Bryonia alba	Medicinal Plant
BXGF05141	Viburnum erubescens	Viburnum erubescens	Medicinal Plant
BXGF05258	Geranium sibiricum	Geranium sibiricum	Medicinal Plant
BXGF05293	Remirea maritima	Remirea maritima	Others
BXGF05297	Isatis tinctoria	Isatis tinctoria	Medicinal Plant
BXGF05301	Baphicacanthus cusia	Baphicacanthus cusia	Medicinal Plant
BXGF05303	Lagerstroemia indica	Lagerstroemia indica	Medicinal Plant
BXGF05364	Arnica mollis	Arnica mollis	Others
BXGF05467	Dalbergia congestiflora	Dalbergia congestiflora	Medicinal Plant
BXGF05498	Croton gratissimus	Croton gratissimus	Medicinal Plant
BXGF05559	Wikstroemia viridiflora	Wikstroemia viridiflora	Medicinal Plant
BXGF05584	Brassica carinata	Brassica carinata	Medicinal Plant
BXGF05722	Hedysarum polybotrys	Hedysarum polybotrys	Medicinal Plant
BXGF05725	Ranunculus asiaticus	Ranunculus asiaticus	Others
BXGF05736	Eurycoma harmandiana	Eurycoma harmandiana	Medicinal Plant
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF05840	Eucalyptus resinifera	Eucalyptus resinifera	Medicinal Plant
BXGF05878	Senecio isatideus	Senecio isatideus	Others
BXGF05927	Schultesia guianensis	Schultesia guianensis	Others
BXGF05990	Carpha glomerata	Carpha glomerata	Others
BXGF06093	Cyanostegia angustifolia	Cyanostegia angustifolia	Others
BXGF06149	Orthosiphon spicatus	Orthosiphon spicatus	Medicinal Plant
BXGF06254	Lysimachia fordiana	Lysimachia fordiana	Others
BXGF06278	Ampelocera edentula	Ampelocera edentula	Others
BXGF06304	Ixeris debilis	Ixeris debilis	Others
BXGF06329	Abies excelsa	Abies excelsa	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}