Showing entry for Cardamomin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0052109
Compound NameCardamomin
Structure
FormulaC16H14O4
InchiKeyNYSZJNUIVUBQMM-BQYQJAHWSA-N
SMILESCOc1cc(O)cc(c1C(=O)/C=C/c1ccccc1)O
InchiInChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+
IUPAC(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
Molecular Weight270.09
Pubchem Id641785
Chembl IdCHEMBL378104
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50185446
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT008716 Potassium voltage-gated channel subfamily A member 3 reviewed Ion channel KCNA3 - 740 - -
reviewed BXGT008716 Potassium voltage-gated channel subfamily A member 3 reviewed Ion channel KCNA3 - 2 - -
reviewed BXGT009390 Genome polyprotein reviewed - 377000 - - -
CHEMBL CHEMBL378104
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P29990 BXGT009390 Genome polyprotein reviewed - Inhibition '=' 39 %
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 14125 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 25929 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 25118 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 25118 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 8912 nM
P29990 BXGT009390 Genome polyprotein reviewed - Ki '=' 377000 nM
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Activity - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 22387 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 21331 nM
Q9YQ12 BXGT022394 Protease unreviewed - protease Inhibition '=' 75 %
Q9YQ12 BXGT022394 Protease unreviewed - protease IC50 '=' 31 ug.mL-1
P29990 BXGT009390 Genome polyprotein reviewed - Inhibition '=' 50 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Activity - - -
P22001 BXGT008716 Potassium voltage-gated channel subfamily A member 3 reviewed Ion channel KCNA3 IC50 '=' 740 nM
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 50118 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 29092 nM
Q77YF9 BXGT016886 Protein Vpr unreviewed - vpr Potency - 14125 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 14125 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 70794 nM
P22001 BXGT008716 Potassium voltage-gated channel subfamily A member 3 reviewed Ion channel KCNA3 IC50 '=' 2 nM
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B reviewed - TNFRSF10B FC '=' 4 -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 14581 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 50118 nM
P29990 BXGT009390 Genome polyprotein reviewed - Inhibition '=' 71 %
Q6W5P4 BXGT016588 Neuropeptide S receptor reviewed - NPSR1 Potency '=' 12589 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 16360 nM
Q9HC16 BXGT020525 DNA dC->dU-editing enzyme APOBEC-3G reviewed Enzyme APOBEC3G Potency - 10000 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 19952 nM
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short reviewed - GNAS Potency - 35481 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 44668 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 20596 nM
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 reviewed Enzyme modulator RAPGEF3 Potency - 70794 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00921 Gaillardia coahuilensis Gaillardia coahuilensis Others
BXGF01250 Colchicum filifolium Colchicum filifolium Others
BXGF01256 Cynoglossum macrostylum Cynoglossum macrostylum Others
BXGF01686 Pulsatilla chinensis Pulsatilla chinensis Medicinal Plant
BXGF02206 Mucuna holtonii Mucuna holtonii Others
BXGF02233 Quercus marilandica Quercus marilandica Medicinal Plant
BXGF02446 Centaurea scoparia Centaurea scoparia Others
BXGF03054 Mimosa pigra Mimosa pigra Medicinal Plant
BXGF03601 Maclura cochinchinensis Maclura cochinchinensis Medicinal Plant
BXGF03920 Kaempferia pandurata Kaempferia pandurata Medicinal Plant
BXGF04035 Campanula choziatowskyi Campanula choziatowskyi Others
BXGF04208 Salvia patens Salvia patens Others
BXGF04214 Dialium excelsum Dialium excelsum Others
BXGF04380 Euphorbia hylonoma Euphorbia hylonoma Others
BXGF04409 Senecio platyphylloides Senecio platyphylloides Others
BXGF04418 Drymaria cordata Drymaria cordata Medicinal Plant
BXGF04436 Podocarpus macrophyllus Podocarpus macrophyllus Medicinal Plant
BXGF04442 Boesenbergia pandurata Boesenbergia pandurata Medicinal Plant
BXGF04447 Helleborus macranthus Helleborus macranthus Others
BXGF04448 Salix rosmarinifolia Salix rosmarinifolia Others
BXGF04455 Heliotropium scabrum Heliotropium scabrum Others
BXGF04457 Podocarpus dacrydioides Podocarpus dacrydioides Medicinal Plant
BXGF04469 Centaurea sonchifolia Centaurea sonchifolia Others
BXGF04472 Matricaria sabulosa Matricaria sabulosa Others
BXGF04489 Pterocaulon serrulatum Pterocaulon serrulatum Medicinal Plant
BXGF04504 Boswellia ovalifoliolata Boswellia ovalifoliolata Medicinal Plant
BXGF04515 Hardenbergia violacea Hardenbergia violacea Medicinal Plant
BXGF04529 Lonchocarpus chiricanus Lonchocarpus chiricanus Others
BXGF04533 Astragalus circassicus Astragalus circassicus Others
BXGF04543 Erythrina hypaphorus Erythrina hypaphorus Others
BXGF04548 Beilschmiedia madang Beilschmiedia madang Medicinal Plant
BXGF04555 Salvia lavanduloides Salvia lavanduloides Others
BXGF04573 Rubia akane Rubia akane Medicinal Plant
BXGF04586 Aniba santalodora Aniba santalodora Others
BXGF04618 Mentzelia decapetala Mentzelia decapetala Human Edible Plant
BXGF04648 Amorphophallus konjac Amorphophallus konjac Human Edible Plant
BXGF05231 Salvia virgata Salvia virgata Human Edible Plant
BXGF05551 Etlingera elatior Etlingera elatior Medicinal Plant
BXGF05566 Petunia axillaris subsp. parodii Petunia axillaris subsp. parodii Medicinal Plant
BXGF06081 Xylopia emarginata Xylopia emarginata Others
BXGF06122 Bethencourtia palmensis Bethencourtia palmensis Others
BXGF06203 Lepechinia urbanii Lepechinia urbanii Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease