Showing entry for Neuropeptide S receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016588
Protein NameNeuropeptide S receptor
Uniport IdQ6W5P4
GeneNPSR1
Gene Id387129
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
molecular function GO:0008188 neuropeptide receptor activity
molecular function GO:0005000 vasopressin receptor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-418555 G alpha (s) signalling events
R-HSA-500792 GPCR ligand binding
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664433 Leishmania parasite growth and survival
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001818 BXGD000080 Agoraphobia Mental Disorders
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001969 BXGD000094 Alcoholic Intoxication Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020624 BXGD001450 Hypomenorrhea Pathological Conditions, Signs and Symptoms
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0026552 BXGD001906 Morphine Dependence Chemically-Induced Disorders; Mental Disorders
C0027341 BXGD001982 Nail-Patella Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0028768 BXGD002084 Obsessive-Compulsive Disorder Mental Disorders
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0035220 BXGD002512 Respiratory Distress Syndrome, Newborn Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0085129 BXGD003128 Bronchial Hyperreactivity Respiratory Tract Diseases
C0149779 BXGD003363 Somatization
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0201512 BXGD004048 Thyroglobulin antibody measurement
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0236736 BXGD004825 Cocaine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0270549 BXGD006079 Generalized Anxiety Disorder Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0559031 BXGD009464 Functional Gastrointestinal Disorders Digestive System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0740903 BXGD010015 allergic symptom
C0751509 BXGD010482 Short Sleeper Syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0815107 BXGD010861 psychological distress
C0852283 BXGD010939 Respiratory Distress Syndrome
C0860603 BXGD011236 Anxiety symptoms
C0861155 BXGD011243 Rhinoconjunctivitis Eye Diseases
C0871388 BXGD011314 social stress Behavior and Behavior Mechanisms
C1135191 BXGD011692 Heart Failure, Systolic Cardiovascular Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1445957 BXGD013081 Serum total cholesterol measurement
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C1837811 BXGD014276 ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 2
C2585575 BXGD017138 Recurrent abdominal pain Pathological Conditions, Signs and Symptoms
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2830004 BXGD017804 Somnolence Pathological Conditions, Signs and Symptoms
C3662483 BXGD019270 Allergic sensitization
C3826320 BXGD019720 Food allergy in children
C3826804 BXGD019734 Abdominal pain in children
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000430 Gossypol 518.55
BXGC0000895 5-Hydroxyindole-3-acetic acid 191.18
BXGC0000988 3' 5'-cyclic AMP 329.21
BXGC0001325 Progesterone 314.46
BXGC0001868 Catechin 290.27
BXGC0001940 Daphnetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0003128 Cotinine 176.22
BXGC0003196 Aripiprazole 448.39
BXGC0003610 5-Hydroxy-L-tryptophan 220.22
BXGC0003707 Estrogen 268.36
BXGC0003992 Imidazoleacrylic acid 138.12
BXGC0004497 3-O-Acetylepisamarcandin 442.54
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0004823 Bis(2-methylpropanoyloxy)-9,10-epoxy-p-mentha-1,3,5-triene 320.38
BXGC0005683 Quercetin 302.24
BXGC0005982 Curcumin 368.38
BXGC0006389 Rotenone 394.42
BXGC0007014 Harman 182.22
BXGC0008365 Colubrinic acid 470.68
BXGC0008667 6-Prenylnaringenin 340.38
BXGC0008707 Isoliquiritigenin 256.25
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0009984 Pyrafoline D 347.45
BXGC0009993 (R)-Mahanine 347.45
BXGC0011377 Eduline 265.31
BXGC0014695 Loratadine 382.14
BXGC0016886 Papaverine Hydrochloride 339.15
BXGC0017757 Androstenedione 286.19
BXGC0019377 Cumingianoside A 738.46
BXGC0023039 (10-Acetyloxy-8,8-Dimethyl-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-9-Yl) 3-Methylbutanoate 388.15
BXGC0024132 1H-Indol-5-Ol 133.05
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0025050 Diethyl 2,6-Dimethyl-4-Phenylpyridine-3,5-Dicarboxylate 327.15
BXGC0025757 Calcimycin 523.27
BXGC0026480 Osajin 404.16
BXGC0026607 epiberberine 336.12
BXGC0027421 Paclitaxel 853.33
BXGC0027544 Gedunin 482.23
BXGC0027854 Ethosuximide 141.08
BXGC0028001 Beta-Lapachone 242.09
BXGC0028067 Enniatin B 639.41
BXGC0029291 Diphyllin 380.09
BXGC0030138 Colchicine 399.17
BXGC0031002 Diffractaic Acid 374.14
BXGC0031326 Paxilline 435.24
BXGC0033960 3-Hydroxybenzo[C]Chromen-6-One 212.05
BXGC0034256 Rottlerin 516.18
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038577 Magnolol 266.13
BXGC0040949 Hydroxyprogesterone Caproate 428.29
BXGC0041218 2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Acetic Acid 198.05
BXGC0041560 Thiram 239.99
BXGC0045252 Sc-560 352.06
BXGC0046510 Tpck 351.07
BXGC0048661 Nicardipine Hydrochloride 479.21
BXGC0049477 Moronic Acid 454.34
BXGC0050651 Cryptotanshinone 296.14
BXGC0051756 [8,8-Dimethyl-9-[(Z)-2-Methylbut-2-Enoyl]Oxy-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-10-Yl] (Z)-2-Methylbut-2-Enoate 426.17
BXGC0052109 Cardamomin 270.09
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein