Showing entry for DNA dC->dU-editing enzyme APOBEC-3G


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020525
Protein NameDNA dC->dU-editing enzyme APOBEC-3G
Uniport IdQ9HC16
GeneAPOBEC3G
Gene Id60489
DomainAPOBEC_C; NAD2
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016553 base conversion or substitution editing
Biological Process GO:0009972 cytidine deamination
Biological Process GO:0016554 cytidine to uridine editing
Biological Process GO:0051607 defense response to virus
Biological Process GO:0070383 DNA cytosine deamination
Biological Process GO:0080111 DNA demethylation
Biological Process GO:0045087 innate immune response
Biological Process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0010529 negative regulation of transposition
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:0048525 negative regulation of viral process
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0016032 viral process
molecular function GO:0004126 cytidine deaminase activity
molecular function GO:0047844 deoxycytidine deaminase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0003723 RNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0030895 apolipoprotein B mRNA editing enzyme complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0000932 P-body
cellular component GO:1990904 ribonucleoprotein complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007867 BXGD000497 Cervix Diseases Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0014378 BXGD000912 Enterovirus Infections Infections
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019189 BXGD001298 Hepatitis, Chronic Digestive System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025007 BXGD001821 Measles Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0035369 BXGD002543 Retroviridae Infections Infections
C0038826 BXGD002779 Superinfection Infections
C0042769 BXGD002999 Virus Diseases Infections
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0237967 BXGD004853 pediatric AIDS Infections; Immune System Diseases
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0343641 BXGD007636 Human papilloma virus infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0497169 BXGD009054 hiv-infection/aids Infections
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0851140 BXGD010916 Carcinoma in situ of uterine cervix Neoplasms
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1141957 BXGD011726 HIV disease progression
C1269955 BXGD012005 Tumor Cell Invasion
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C3714514 BXGD019409 Infection Infections
C3826758 BXGD019733 AIDS (Disease)
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000194 Sanguinarine 332.33
BXGC0000436 Glycerol 92.09
BXGC0000655 Harmalol 200.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001428 Piperlongine 317.34
BXGC0001691 Questiomycin A 212.2
BXGC0001742 Eupafolin 316.26
BXGC0001929 (R)-3',7-Dihydroxy-2',4'-dimethoxyisoflavan 302.32
BXGC0002588 Magnesium 24.31
BXGC0003396 Legumelin 394.42
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0003696 Quercetin 3-O-methyl-ether 316.26
BXGC0003705 Chloride 35.45
BXGC0003707 Estrogen 268.36
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005659 Arachidonic acid 304.47
BXGC0005721 Bisdemethoxycurcumin 308.33
BXGC0005879 Eugenol 164.2
BXGC0005982 Curcumin 368.38
BXGC0006107 alpha-Linolenic acid 278.43
BXGC0006306 Myricetin 318.24
BXGC0007029 Emodin 270.24
BXGC0013582 Curcumin 368.13
BXGC0014059 2-Methoxy-1,4-Naphthoquinone 188.05
BXGC0014455 Fanchinin 622.3
BXGC0014976 securinine 217.11
BXGC0017277 Aurin 290.09
BXGC0017933 Sulfuretin 270.05
BXGC0019348 Angustibalin 304.13
BXGC0019930 Baccatin III 586.24
BXGC0020076 pterosin C 3-O-glucoside 396.18
BXGC0020737 Protoapigenone 286.05
BXGC0020873 Aromaticin 246.13
BXGC0023633 Kamebanin 334.21
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0024813 Demethoxycurcumin 338.12
BXGC0025090 Matsukaze lactone 350.08
BXGC0025394 Scoulerine 327.15
BXGC0026471 Coronopilin 264.14
BXGC0026758 Santin 344.09
BXGC0028727 noscapine 413.15
BXGC0029601 EUPAROTIN ACETATE 418.16
BXGC0030010 Michler's Ketone 268.16
BXGC0030469 10-Deacetylbaccatin III 544.23
BXGC0032634 Chlorothalonil 263.88
BXGC0034968 Dienestrol 266.13
BXGC0035226 Betulinic Acid 456.36
BXGC0036860 Helenalin 262.12
BXGC0036864 Cyclovalone 366.15
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038546 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 346.14
BXGC0039520 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate 360.16
BXGC0040358 Lobaric Acid 456.18
BXGC0041560 Thiram 239.99
BXGC0042110 4-(4-DIMETHYLAMINOSTYRYL)QUINOLINE 274.15
BXGC0042127 Oxyquinoline 145.05
BXGC0042143 Methyl 6,18-Dimethoxy-17-(3,4,5-Trimethoxybenzoyl)Oxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 608.27
BXGC0042678 Ambrosin 246.13
BXGC0042870 Piceatannol 244.07
BXGC0044200 Menadione 172.05
BXGC0045812 Trifluoperazine 407.16
BXGC0046510 Tpck 351.07
BXGC0047186 (2S,3S)-2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxy-2,3-Dihydrochromen-4-One 450.12
BXGC0049633 4-Aminophenol 109.05
BXGC0049858 Chalcone 208.09
BXGC0051013 N-Phenylnaphthalen-1-Amine 219.1
BXGC0052109 Cardamomin 270.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein