Showing entry for Tumors of Adrenal Cortex


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000063
Disease NameTumors of Adrenal Cortex
Disease CUI IdC0001618
MeSH Codes C04   C19  
Disease Class NameNeoplasms; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0000818   HP:0002664  
Human Phenotype Ontology TermAbnormality of the endocrine system; Neoplasm
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60566 BXGT004884 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 701 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 9133 reviewed Enzyme modulator
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04899 BXGT006281 Guanine nucleotide-binding protein G(i) subunit alpha-2 2771 reviewed Enzyme modulator
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08133 BXGT006727 Annexin A6 309 reviewed
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12830 BXGT007852 Cadherin-1 999 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17844 BXGT008346 Probable ATP-dependent RNA helicase DDX5 1655 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P29401 BXGT009344 Transketolase 7086 reviewed Enzyme
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
Q00526 BXGT012531 Cyclin-dependent kinase 3 1018 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01718 BXGT012609 Adrenocorticotropic hormone receptor 4158 reviewed G-protein coupled receptor
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease