Showing entry for G2/mitotic-specific cyclin-B2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005347
Protein NameG2/mitotic-specific cyclin-B2
Uniport IdO95067
GeneCCNB2
Gene Id9133
DomainCyclin_C; Cyclin_N
Pfam PF02984   PF00134  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04110 Cell cycle
4. Cellular Processes 4.2 Cell growth and death hsa04114 Oocyte meiosis
4. Cellular Processes 4.2 Cell growth and death hsa04115 p53 signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04218 Cellular senescence
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0044772 mitotic cell cycle phase transition
Biological Process GO:0007077 mitotic nuclear envelope disassembly
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Process GO:0040008 regulation of growth
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0048538 thymus development
molecular function GO:0045296 cadherin binding
molecular function GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
cellular component GO:0005813 centrosome
cellular component GO:0000307 cyclin-dependent protein kinase holoenzyme complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0042025 host cell nucleus
cellular component GO:0016020 membrane
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-156711 Polo-like kinase mediated events
R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization
R-HSA-1640170 Cell Cycle
R-HSA-1640170 Cell Cycle
R-HSA-2500257 Resolution of Sister Chromatid Cohesion
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-2555396 Mitotic Metaphase and Anaphase
R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
R-HSA-2980766 Nuclear Envelope Breakdown
R-HSA-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
R-HSA-2995383 Initiation of Nuclear Envelope (NE) Reformation
R-HSA-2995410 Nuclear Envelope (NE) Reassembly
R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-68875 Mitotic Prophase
R-HSA-68875 Mitotic Prophase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68882 Mitotic Anaphase
R-HSA-68886 M Phase
R-HSA-68886 M Phase
R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69478 G2/M DNA replication checkpoint
R-HSA-69481 G2/M Checkpoints
R-HSA-69620 Cell Cycle Checkpoints
R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001618 BXGD000063 Tumors of Adrenal Cortex Neoplasms; Endocrine System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149978 BXGD003397 Adenocarcinoma of rectum Digestive System Diseases; Neoplasms
C0206681 BXGD004236 Adenocarcinoma, Clear Cell Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0001545 Harmine 212.25
BXGC0002071 Apigenin 270.24
BXGC0004342 (E)-3-(2-Hydroxyphenyl)-2-propenal 148.16
BXGC0005683 Quercetin 302.24
BXGC0006635 Luteolin 286.24
BXGC0007052 Olomoucine 298.34
BXGC0008167 Chrysin 254.24
BXGC0027547 Indigo 262.07
BXGC0040305 Indirubin 262.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein