adisease

Showing entry for Rectal Neoplasms

General Disease Information
BXGD Id	BXGD002490
Disease Name	Rectal Neoplasms
Disease CUI Id	C0034885
MeSH Codes	C06 C04
Disease Class Name	Digestive System Diseases; Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0025031 HP:0002664
Human Phenotype Ontology Term	Abnormality of the digestive system; Neoplasm
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12830	BXGT007852	Cadherin-1	999	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16070	BXGT008186	CD44 antigen	960	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P54868	BXGT011090	Hydroxymethylglutaryl-CoA synthase, mitochondrial	3158	reviewed
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96FJ2	BXGT019659	Dynein light chain 2, cytoplasmic	140735	reviewed	Cellular structure
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UGJ0	BXGT021683	5'-AMP-activated protein kinase subunit gamma-2	51422	reviewed	Enzyme modulator
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}