Showing entry for Dual specificity mitogen-activated protein kinase kinase 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004087
Protein NameDual specificity mitogen-activated protein kinase kinase 7
Uniport IdO14733
GeneMAP2K7
Gene Id5609
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04012 ErbB signaling pathway
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04620 Toll-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04660 T cell receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04664 Fc epsilon RI signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04668 TNF signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04722 Neurotrophin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04912 GnRH signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05161 Hepatitis B
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05169 Epstein-Barr virus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0006915 apoptotic process
Biological Process GO:0038095 Fc-epsilon receptor signaling pathway
Biological Process GO:0007254 JNK cascade
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0051973 positive regulation of telomerase activity
Biological Process GO:1904355 positive regulation of telomere capping
Biological Process GO:0032212 positive regulation of telomere maintenance via telomerase
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0009408 response to heat
Biological Process GO:0006970 response to osmotic stress
Biological Process GO:0034612 response to tumor necrosis factor
Biological Process GO:0009411 response to UV
Biological Process GO:0007165 signal transduction
Biological Process GO:0051403 stress-activated MAPK cascade
molecular function GO:0005524 ATP binding
molecular function GO:0019899 enzyme binding
molecular function GO:0008545 JUN kinase kinase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0004708 MAP kinase kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0004713 protein tyrosine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1643685 Disease
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
R-HSA-166166 MyD88-independent TLR4 cascade
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-2262752 Cellular responses to stress
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2559580 Oxidative Stress Induced Senescence
R-HSA-2559583 Cellular Senescence
R-HSA-2871796 FCERI mediated MAPK activation
R-HSA-448424 Interleukin-17 signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-450294 MAP kinase activation
R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
R-HSA-5210891 Uptake and function of anthrax toxins
R-HSA-5339562 Uptake and actions of bacterial toxins
R-HSA-5663205 Infectious disease
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-975871 MyD88 cascade initiated on plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002448 BXGD000115 Ameloblastoma Neoplasms
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007130 BXGD000440 Mucinous Adenocarcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010276 BXGD000659 Craniopharyngioma Neoplasms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011848 BXGD000750 Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014116 BXGD000892 Endocardial Cushion Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014378 BXGD000912 Enterovirus Infections Infections
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0016059 BXGD001043 Fibrosis Pathological Conditions, Signs and Symptoms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018202 BXGD001183 Granulomatous Angiitis Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019618 BXGD001339 Histiocytosis Hemic and Lymphatic Diseases
C0019621 BXGD001340 Histiocytosis, Langerhans-Cell Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0019624 BXGD001342 Histiocytosis, Non-Langerhans-Cell Hemic and Lymphatic Diseases
C0019625 BXGD001343 Sinus histiocytosis Hemic and Lymphatic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022572 BXGD001553 keratoacanthoma Skin and Connective Tissue Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023212 BXGD001616 Left-Sided Heart Failure Cardiovascular Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023443 BXGD001648 Hairy Cell Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023480 BXGD001664 Leukemia, Myelomonocytic, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024291 BXGD001757 Lymphohistiocytosis, Hemophagocytic Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0024796 BXGD001806 Marfan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0027962 BXGD002064 Melanocytic nevus Neoplasms
C0028326 BXGD002075 Noonan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029458 BXGD002158 Osteoporosis, Postmenopausal Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0030326 BXGD002209 Panniculitis Skin and Connective Tissue Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031118 BXGD002286 Peripheral Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033822 BXGD002430 Pseudomyxoma Peritonei Neoplasms
C0034494 BXGD002481 Rabies (disorder) Infections
C0034885 BXGD002490 Rectal Neoplasms Digestive System Diseases; Neoplasms
C0035112 BXGD002508 Reoviridae Infections Infections
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0035869 BXGD002569 Rotavirus Infections Infections
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040188 BXGD002850 Tic disorder Nervous System Diseases; Mental Disorders
C0042164 BXGD002965 Uveitis Eye Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153392 BXGD003630 Malignant neoplasm of nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0153467 BXGD003653 Malignant tumor of peritoneum Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0162830 BXGD003987 Dermatitis, Phototoxic Skin and Connective Tissue Diseases
C0175704 BXGD004010 LEOPARD Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206656 BXGD004219 Embryonal Rhabdomyosarcoma Neoplasms
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206701 BXGD004251 Cystadenocarcinoma, Serous Neoplasms
C0206728 BXGD004273 Plexiform Neurofibroma Neoplasms; Nervous System Diseases
C0206739 BXGD004283 Epithelioid and spindle cell nevus Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220603 BXGD004293 Childhood Brain Neoplasm Neoplasms; Nervous System Diseases
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220613 BXGD004297 Adult Soft Tissue Sarcoma
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220645 BXGD004307 Childhood Soft Tissue Sarcoma
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221013 BXGD004363 Mastocytosis, Systemic Neoplasms; Immune System Diseases
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234533 BXGD004687 Generalized seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235394 BXGD004744 Wasting Nutritional and Metabolic Diseases
C0235527 BXGD004753 Heart Failure, Right-Sided Cardiovascular Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238301 BXGD004909 Cancer of Nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0272401 BXGD006365 Virchow's node (disorder)
C0278076 BXGD006493 Behavioral tic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278519 BXGD006531 Recurrent Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0278579 BXGD006537 Cervix carcinoma recurrent Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0278592 BXGD006544 Adult Angiosarcoma Neoplasms
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0278652 BXGD006554 Childhood Craniopharyngioma Neoplasms
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0278875 BXGD006606 Adult Craniopharyngioma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278882 BXGD006613 Stage III Cutaneous Melanoma AJCC v6
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0279988 BXGD006707 Childhood Angiosarcoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280321 BXGD006739 Squamous cell carcinoma of the hypopharynx
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280483 BXGD006750 Adult Anaplastic Astrocytoma Neoplasms
C0280781 BXGD006758 Adult Pilocytic Astrocytoma Neoplasms
C0282313 BXGD006803 Condition, Preneoplastic Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0334583 BXGD007124 Pilocytic Astrocytoma Neoplasms
C0334586 BXGD007126 Pleomorphic Xanthoastrocytoma Neoplasms
C0334663 BXGD007149 Histiocytic sarcoma Neoplasms; Hemic and Lymphatic Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339383 BXGD007245 Choroidal and/or chorioretinal disorder Eye Diseases
C0340643 BXGD007357 Dissection of aorta Cardiovascular Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0345960 BXGD007752 Giant cell carcinoma of lung Neoplasms
C0346326 BXGD007811 Optic Nerve Glioma Neoplasms; Eye Diseases; Nervous System Diseases
C0346360 BXGD007815 Malignant melanoma of conjunctiva
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0346619 BXGD007829 Malignant neoplasm of cardioesophageal junction of stomach Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349639 BXGD007943 Juvenile Myelomonocytic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376154 BXGD007980 Skin callus Skin and Connective Tissue Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0398597 BXGD008198 Histiocytic syndrome Immune System Diseases; Hemic and Lymphatic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431112 BXGD008660 Anaplastic ganglioglioma Neoplasms
C0431128 BXGD008664 Papillary craniopharyngioma Neoplasms
C0431129 BXGD008665 Adamantinous Craniopharyngioma Neoplasms
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0521698 BXGD009165 Vogt-Koyanagi-Harada like syndrome Eye Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549410 BXGD009378 Palmar-plantar erythrodysesthesia syndrome Skin and Connective Tissue Diseases; Chemically-Induced Disorders
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0585362 BXGD009592 Squamous cell carcinoma of mouth Digestive System Diseases; Neoplasms; Stomatognathic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0587248 BXGD009617 Costello syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0677936 BXGD009737 Refractory cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699753 BXGD009864 Cancer Relapse
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C0750974 BXGD010270 Brain Tumor, Primary Neoplasms; Nervous System Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0796004 BXGD010776 Kabuki make-up syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Otorhinolaryngologic Diseases; Hemic and Lymphatic Diseases
C0796418 BXGD010832 Visual Pathway Glioma Neoplasms
C0852711 BXGD010951 Sickle Cell Dactylitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Chemically-Induced Disorders; Hemic and Lymphatic Diseases
C0860564 BXGD011231 Retinoic acid syndrome Pathological Conditions, Signs and Symptoms
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0877104 BXGD011335 Retinal toxicity
C0878675 BXGD011384 Erdheim-Chester Disease Hemic and Lymphatic Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1112160 BXGD011649 Gastrooesophageal cancer
C1136084 BXGD011708 Plasma cell dyscrasia Immune System Diseases; Hemic and Lymphatic Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1167791 BXGD011776 Skin toxicity
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1266089 BXGD011954 Metaplastic carcinoma Neoplasms
C1266184 BXGD011991 Atypical Teratoid Rhabdoid Tumor Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1275081 BXGD012056 Cardio-facio-cutaneous syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1321872 BXGD012446 Stage IV Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332460 BXGD012530 Barrett's Adenocarcinoma
C1332888 BXGD012550 Central nervous system melanoma
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1332995 BXGD012575 Childhood Pilocytic Astrocytoma Neoplasms
C1333749 BXGD012638 Gallbladder Melanoma Digestive System Diseases; Neoplasms
C1333990 BXGD012670 Hereditary Nonpolyposis Colorectal Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1337013 BXGD012876 Differentiated Thyroid Gland Carcinoma
C1384494 BXGD012939 Metastatic Carcinoma Pathological Conditions, Signs and Symptoms; Neoplasms
C1455705 BXGD013103 Pulmonary Histiocytosis X Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C1456868 BXGD013128 Diabetic foot ulcer Skin and Connective Tissue Diseases; Endocrine System Diseases; Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1512127 BXGD013185 HER2 gene amplification
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1531553 BXGD013297 Dendritic cell neoplasm Neoplasms; Hemic and Lymphatic Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1841972 BXGD014484 Glucocorticoid Receptor Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1842036 BXGD014490 GIANT PIGMENTED HAIRY NEVUS Neoplasms; Skin and Connective Tissue Diseases
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1851710 BXGD015226 LATERAL MENINGOCELE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1861305 BXGD016027 TARSAL-CARPAL COALITION SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1863753 BXGD016197 LIMB-MAMMARY SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1959583 BXGD016637 Myocardial Failure Cardiovascular Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961112 BXGD016674 Heart Decompensation Cardiovascular Diseases
C1997217 BXGD016859 Low grade glioma Neoplasms
C2062441 BXGD016897 Influenza A
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2169806 BXGD016935 recurrent muscle twitches (symptom) Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2613439 BXGD017184 Extramedullary Hematopoiesis (disorder) Hemic and Lymphatic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2826323 BXGD017790 Refractory Cytopenia of Childhood
C2931019 BXGD017938 Split hand foot deformity 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3267126 BXGD018615 Trichodysplasia spinulosa
C3272528 BXGD018624 Small Intestinal Neuroendocrine Tumor
C3272607 BXGD018627 Colorectal Neuroendocrine Carcinoma Digestive System Diseases; Neoplasms
C3495721 BXGD019001 Spitzoid melanoma
C3539781 BXGD019086 Progressive cGVHD
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3544205 BXGD019109 Ovarian clear cell carcinoma
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C3898127 BXGD020061 Non-Metastatic Childhood Soft Tissue Sarcoma
C3899645 BXGD020087 Childhood Pleomorphic Xanthoastrocytoma
C3900111 BXGD020111 Acute motor sensory axonal neuropathy Immune System Diseases; Nervous System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4054188 BXGD021977 Ph-Like Acute Lymphoblastic Leukemia
C4054727 BXGD021988 Infant Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4087504 BXGD022156 Peritoneal dissemination
C4282128 BXGD022420 PATENT DUCTUS ARTERIOSUS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4283978 BXGD022427 Primary adenocarcinoma of lower third of esophagus due to Barrett esophagus
C4284013 BXGD022428 Primary cholangiocarcinoma of intrahepatic biliary tract Neoplasms
C4289580 BXGD022491 Epithelioid glioblastoma
C4290046 BXGD022507 trachomatis
C4520732 BXGD023037 Stage IV Cutaneous Melanoma AJCC v6 and v7
C4524268 BXGD023104 Advanced lung cancer
C4528668 BXGD023176 Acute myeloid leukaemia refractory Neoplasms
C4551548 BXGD023342 Grade III Childhood Astrocytoma Neoplasms
C4551602 BXGD023369 Noonan Syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4551687 BXGD023392 Sarcoma of soft tissue Neoplasms
C4552100 BXGD023488 Lynch Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C4684879 BXGD023576 Metastatic Bile Duct Carcinoma Digestive System Diseases; Neoplasms
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722172 BXGD023791 Primary differentiated carcinoma of thyroid gland
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4725091 BXGD023828 metastatic intraocular melanoma Neoplasms; Eye Diseases
C4725092 BXGD023829 Advanced Uveal Melanoma
C4726609 BXGD023846 Resectable Pancreatic Ductal Adenocarcinoma
C4727838 BXGD023874 Advanced Melanoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0012352 Chelerythrine 348.12
BXGC0030612 tetraethylene glycol 194.12
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein