adisease

Showing entry for HELLP Syndrome

General Disease Information
BXGD Id	BXGD003979
Disease Name	HELLP Syndrome
Disease CUI Id	C0162739
MeSH Codes	C13
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00751	BXGT005643	Complement factor B	629	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P07093	BXGT006544	Glia-derived nexin	5270	reviewed	Enzyme modulator
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P08603	BXGT006798	Complement factor H	3075	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13641	BXGT013390	Trophoblast glycoprotein	7162	reviewed	Receptor
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NZD4	BXGT021271	Alpha-hemoglobin-stabilizing protein	51327	reviewed	Chaperone
Q9UHV8	BXGT021706	Galactoside-binding soluble lectin 13	29124	reviewed	Signaling
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}