Showing entry for Transforming growth factor beta-3 proprotein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007584
Protein NameTransforming growth factor beta-3 proprotein
Uniport IdP10600
GeneTGFB3
Gene Id7043
DomainTGFb_propeptide; TGF_beta
Pfam PF00019   PF00688  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04110 Cell cycle
4. Cellular Processes 4.2 Cell growth and death hsa04218 Cellular senescence
3. Environmental Information Processing 3.2 Signal transduction hsa04350 TGF-beta signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04933 AGE-RAGE signaling pathway in diabetic complications
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05140 Leishmaniasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05144 Malaria
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05145 Toxoplasmosis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05161 Hepatitis B
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05210 Colorectal cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05211 Renal cell carcinoma
6. Human Diseases 6.2 Cancers: Specific types hsa05212 Pancreatic cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05220 Chronic myeloid leukemia
6. Human Diseases 6.2 Cancers: Specific types hsa05225 Hepatocellular carcinoma
6. Human Diseases 6.2 Cancers: Specific types hsa05226 Gastric cancer
6. Human Diseases 6.3 Immune diseases hsa05321 Inflammatory bowel disease (IBD)
6. Human Diseases 6.3 Immune diseases hsa05323 Rheumatoid arthritis
6. Human Diseases 6.6 Cardiovascular diseases hsa05410 Hypertrophic cardiomyopathy (HCM)
6. Human Diseases 6.6 Cardiovascular diseases hsa05414 Dilated cardiomyopathy (DCM)
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0007568 aging
Biological Process GO:0030509 BMP signaling pathway
Biological Process GO:0045216 cell-cell junction organization
Biological Process GO:0070483 detection of hypoxia
Biological Process GO:0048565 digestive tract development
Biological Process GO:0048702 embryonic neurocranium morphogenesis
Biological Process GO:0060325 face morphogenesis
Biological Process GO:0007565 female pregnancy
Biological Process GO:0060364 frontal suture morphogenesis
Biological Process GO:0048839 inner ear development
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0048286 lung alveolus development
Biological Process GO:0030879 mammary gland development
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010936 negative regulation of macrophage cytokine production
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
Biological Process GO:0042476 odontogenesis
Biological Process GO:0043932 ossification involved in bone remodeling
Biological Process GO:0002576 platelet degranulation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:0051781 positive regulation of cell division
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032967 positive regulation of collagen biosynthetic process
Biological Process GO:0010718 positive regulation of epithelial to mesenchymal transition
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0060391 positive regulation of SMAD protein signal transduction
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:1905075 positive regulation of tight junction disassembly
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0043627 response to estrogen
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0034616 response to laminar fluid shear stress
Biological Process GO:0032570 response to progesterone
Biological Process GO:0007435 salivary gland morphogenesis
Biological Process GO:0062009 secondary palate development
Biological Process GO:0060395 SMAD protein signal transduction
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway
Biological Process GO:0042704 uterine wall breakdown
Biological Process GO:0042060 wound healing
molecular function GO:0005125 cytokine activity
molecular function GO:0008083 growth factor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0050431 transforming growth factor beta binding
molecular function GO:0034714 type III transforming growth factor beta receptor binding
molecular function GO:0005114 type II transforming growth factor beta receptor binding
molecular function GO:0034713 type I transforming growth factor beta receptor binding
cellular component GO:0009986 cell surface
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0043025 neuronal cell body
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0031093 platelet alpha granule lumen
cellular component GO:0030315 T-tubule
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-1474244 Extracellular matrix organization
R-HSA-1474244 Extracellular matrix organization
R-HSA-1566948 Elastic fibre formation
R-HSA-2129379 Molecules associated with elastic fibres
R-HSA-3000178 ECM proteoglycans
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003706 BXGD000215 Arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0008476 BXGD000543 Chondromatosis, Synovial Musculoskeletal Diseases
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0013238 BXGD000806 Dry Eye Syndromes Eye Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013405 BXGD000834 Dyspnea, Paroxysmal Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Cardiovascular Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015302 BXGD000974 External exotoses Musculoskeletal Diseases
C0015310 BXGD000976 Exotropia Eye Diseases; Nervous System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016059 BXGD001043 Fibrosis Pathological Conditions, Signs and Symptoms
C0016202 BXGD001050 Flatfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0019079 BXGD001278 Hemoptysis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019243 BXGD001308 Angioedemas, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases; Cardiovascular Diseases
C0019294 BXGD001314 Hernia, Inguinal Pathological Conditions, Signs and Symptoms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020608 BXGD001443 Hypodontia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024796 BXGD001806 Marfan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0026265 BXGD001894 Diseases of mitral valve Cardiovascular Diseases
C0026266 BXGD001895 Mitral Valve Insufficiency Cardiovascular Diseases
C0026269 BXGD001897 Mitral Valve Stenosis Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029427 BXGD002144 Synovial osteochondromatosis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0032326 BXGD002351 Pneumothorax Respiratory Tract Diseases
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035238 BXGD002520 Congenital abnormality of respiratory system Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0078911 BXGD003053 AIDS-Associated Nephropathy Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases; Immune System Diseases
C0085119 BXGD003127 Foot Ulcer Skin and Connective Tissue Diseases
C0085298 BXGD003155 Sudden Cardiac Death Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0149630 BXGD003334 Bicuspid aortic valve Cardiovascular Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151888 BXGD003497 Hyporeflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0153687 BXGD003683 Secondary malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0156181 BXGD003841 Peritoneal adhesion Digestive System Diseases; Skin and Connective Tissue Diseases
C0158646 BXGD003897 Cleft palate with cleft lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0158731 BXGD003902 Congenital pectus carinatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0162739 BXGD003979 HELLP Syndrome Female Urogenital Diseases and Pregnancy Complications
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0175703 BXGD004009 Thrombocytopenia-Absent Radius Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Hemic and Lymphatic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202236 BXGD004086 Triglycerides measurement
C0206172 BXGD004168 Diabetic Foot Skin and Connective Tissue Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220996 BXGD004358 Infantile scurvy Nutritional and Metabolic Diseases
C0231807 BXGD004524 Dyspnea on exertion Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0236734 BXGD004823 Caffeine related disorders
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0241240 BXGD005089 Tall stature
C0242698 BXGD005189 Ventricular Dysfunction, Left Cardiovascular Diseases
C0263401 BXGD005298 Cutis marmorata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Cardiovascular Diseases; Wounds and Injuries
C0263912 BXGD005354 Rotator cuff syndrome Wounds and Injuries
C0265706 BXGD005570 Gastroschisis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0272170 BXGD006312 Shwachman syndrome
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0314719 BXGD006890 Dryness of eye Eye Diseases
C0334299 BXGD007027 Carcinoid tumor no ICD-O subtype Neoplasms
C0339263 BXGD007231 Pseudophakic corneal edema Eye Diseases
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0340164 BXGD007305 Lofgrens syndrome Hemic and Lymphatic Diseases
C0344424 BXGD007669 Ventricular Arrhythmia by ECG Finding
C0349588 BXGD007933 Short stature
C0349788 BXGD007956 Arrhythmogenic Right Ventricular Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0399440 BXGD008244 Hereditary gingival fibromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0489786 BXGD009018 Height
C0521158 BXGD009130 Recurrent tumor
C0521170 BXGD009131 Osteoporotic Fractures Wounds and Injuries
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0542514 BXGD009277 Blue sclera Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0546884 BXGD009345 Hypovolemia Pathological Conditions, Signs and Symptoms
C0574143 BXGD009503 Liver calculus
C0595936 BXGD009628 Aqueous Humor Disorders Eye Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0729233 BXGD009922 Dissecting aneurysm of the thoracic aorta Cardiovascular Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0810364 BXGD010846 Cleft Lip with or without Cleft Palate
C0852036 BXGD010934 Pregnancy associated hypertension Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1096458 BXGD011622 Vascular occlusion Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1275685 BXGD012092 Avellino corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1298820 BXGD012252 Aneurysm of aortic root Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1337014 BXGD012877 Grade I Chondrosarcoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1388233 BXGD012961 Aneurysm of descending thoracic aorta Cardiovascular Diseases
C1445957 BXGD013081 Serum total cholesterol measurement
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1519689 BXGD013245 Tumor Promotion Pathological Conditions, Signs and Symptoms; Neoplasms
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1812607 BXGD013761 Aortic aneurysm and dissection
C1832931 BXGD013885 ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1836635 BXGD014140 Loeys-Dietz Aortic Aneurysm Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Cardiovascular Diseases
C1836653 BXGD014143 Ascending aortic dissection Cardiovascular Diseases
C1837108 BXGD014199 Decreased muscle mass
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1837404 BXGD014229 High, narrow palate
C1851712 BXGD015227 Dural ectasia
C1855794 BXGD015546 Bamforth syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Endocrine System Diseases; Stomatognathic Diseases
C1860493 BXGD015987 Abnormality of the sternum
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C1862382 BXGD016125 SVEINSSON CHORIORETINAL ATROPHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1862511 BXGD016134 ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 1 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1883529 BXGD016597 Ventricular Arrhythmia, CTCAE 3.0
C1956089 BXGD016615 Osteophyte Musculoskeletal Diseases
C2063326 BXGD016902 Right ventricular cardiomyopathy Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2697932 BXGD017440 Loeys-Dietz Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Cardiovascular Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2981150 BXGD018211 Uranostaphyloschisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3489393 BXGD018928 Hiatal Hernia Pathological Conditions, Signs and Symptoms
C3494422 BXGD018966 Retrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C3553762 BXGD019186 LOEYS-DIETZ SYNDROME 4
C3711374 BXGD019382 Nonsyndromic Deafness Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C3810012 BXGD019628 RIENHOFF SYNDROME
C3810018 BXGD019629 Bilateral coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4016411 BXGD020327 ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA 1
C4021813 BXGD020799 Oral cleft
C4022729 BXGD020969 Increased arm span
C4022878 BXGD021026 Descending aortic dissection Cardiovascular Diseases
C4025272 BXGD021615 Peripheral arterial stenosis
C4025690 BXGD021734 Prenatal maternal abnormality
C4025845 BXGD021825 Abnormality iris morphology
C4321245 BXGD022744 Cleft lip or lips
C4476540 BXGD022824 Dilatation of the cerebral artery Nervous System Diseases; Cardiovascular Diseases
C4476554 BXGD022829 Carotid artery dilatation
C4551487 BXGD023313 Submucous cleft palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C4551955 BXGD023447 Loeys-Dietz Syndrome, Type 1a Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Cardiovascular Diseases
C4553764 BXGD023550 Ventricular Arrhythmia, CTCAE 5.0
C4703646 BXGD023675 Eosinophilic infiltration of the esophagus Digestive System Diseases
C4707243 BXGD023712 Familial thoracic aortic aneurysm and aortic dissection
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
BXGC0042315 1,4-dioxane 88.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein