Showing entry for Giant Cell Tumor of Bone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004203
Disease NameGiant Cell Tumor of Bone
Disease CUI IdC0206638
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0002664   HP:0000924  
Human Phenotype Ontology TermNeoplasm; Abnormality of the skeletal system
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P51884 BXGT010903 Lumican 4060 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P84243 BXGT012052 Histone H3.3 3021 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q03405 BXGT012713 Urokinase plasminogen activator surface receptor 5329 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q15084 BXGT013536 Protein disulfide-isomerase A6 10130 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease