Showing entry for Proteinase-activated receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009025
Protein NameProteinase-activated receptor 1
Uniport IdP25116
GeneF2R
Gene Id2149
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0009653 anatomical structure morphogenesis
Biological Process GO:0007596 blood coagulation
Biological Process GO:0045217 cell-cell junction maintenance
Biological Process GO:0002248 connective tissue replacement involved in inflammatory response wound healing
Biological Process GO:0007529 establishment of synaptic specificity at neuromuscular junction
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0048873 homeostasis of number of cells within a tissue
Biological Process GO:0006954 inflammatory response
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0003105 negative regulation of glomerular filtration
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1900134 negative regulation of renin secretion into blood stream
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0030168 platelet activation
Biological Process GO:0060155 platelet dense granule organization
Biological Process GO:0030194 positive regulation of blood coagulation
Biological Process GO:0051928 positive regulation of calcium ion transport
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032967 positive regulation of collagen biosynthetic process
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0035025 positive regulation of Rho protein signal transduction
Biological Process GO:0045987 positive regulation of smooth muscle contraction
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0030193 regulation of blood coagulation
Biological Process GO:0032651 regulation of interleukin-1 beta production
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0009611 response to wounding
Biological Process GO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0031681 G-protein beta-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0015057 thrombin-activated receptor activity
cellular component GO:0005901 caveola
cellular component GO:0009986 cell surface
cellular component GO:0005769 early endosome
cellular component GO:0005576 extracellular region
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005770 late endosome
cellular component GO:0031594 neuromuscular junction
cellular component GO:0005886 plasma membrane
cellular component GO:0031094 platelet dense tubular network
cellular component GO:0045211 postsynaptic membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-109582 Hemostasis
R-HSA-140875 Common Pathway of Fibrin Clot Formation
R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade)
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-500792 GPCR ligand binding
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76002 Platelet activation, signaling and aggregation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000833 BXGD000014 Abscess Pathological Conditions, Signs and Symptoms; Infections
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003855 BXGD000227 Arteriovenous fistula Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0005956 BXGD000356 Bone Marrow Diseases Hemic and Lymphatic Diseases
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007140 BXGD000447 Carcinosarcoma Neoplasms
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0008039 BXGD000512 Cheyne-Stokes Respiration Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010072 BXGD000649 Coronary Thrombosis Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0012546 BXGD000776 Diphtheria Infections
C0012739 BXGD000786 Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017185 BXGD001104 Gastrointestinal Neoplasms Digestive System Diseases; Neoplasms
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017525 BXGD001112 Giant Cell Tumors Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020651 BXGD001460 Hypotension, Orthostatic Nervous System Diseases; Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0022876 BXGD001591 Premature Obstetric Labor Female Urogenital Diseases and Pregnancy Complications
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023343 BXGD001635 Leprosy Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023443 BXGD001648 Hairy Cell Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023474 BXGD001662 Leukemia, Myeloid, Chronic-Phase Neoplasms; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027121 BXGD001973 Myositis Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027659 BXGD002012 Neoplasms, Experimental Neoplasms
C0027668 BXGD002019 Neoplasms, Vascular Tissue Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031269 BXGD002297 Peutz-Jeghers Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0032897 BXGD002378 Prader-Willi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0033036 BXGD002389 Atrial Premature Complexes Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037928 BXGD002713 Spinal Cord Diseases Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040558 BXGD002873 Toxoplasmosis Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041408 BXGD002923 Turner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042798 BXGD003003 Low Vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0079504 BXGD003080 Hermanski-Pudlak Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085409 BXGD003168 Polyendocrinopathies, Autoimmune Immune System Diseases; Endocrine System Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085758 BXGD003250 Aganglionosis, Colonic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149939 BXGD003390 Obstructive nephropathy Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152171 BXGD003552 Idiopathic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155773 BXGD003820 Portal Vein Thrombosis Cardiovascular Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0206638 BXGD004203 Giant Cell Tumor of Bone Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235989 BXGD004801 Renal interstitial fibrosis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242852 BXGD005197 Proliferative vitreoretinopathy Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264545 BXGD005400 Thickening of pleura Respiratory Tract Diseases
C0265101 BXGD005454 Carotid artery occlusion Nervous System Diseases; Cardiovascular Diseases
C0265309 BXGD005511 Leri-Weill dyschondrosteosis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0268318 BXGD005896 Cholestasis of pregnancy Digestive System Diseases; Female Urogenital Diseases and Pregnancy Complications
C0272302 BXGD006340 Gray Platelet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0276138 BXGD006403 Viral myocarditis Infections; Cardiovascular Diseases
C0277524 BXGD006468 Infectious colitis Digestive System Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280141 BXGD006716 Acute Undifferentiated Leukemia
C0280280 BXGD006731 stage, prostate cancer Neoplasms; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0343378 BXGD007617 Helicobacter-associated gastritis Digestive System Diseases; Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345964 BXGD007755 Adenoma of lung Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0398623 BXGD008202 Thrombophilia Hemic and Lymphatic Diseases
C0399440 BXGD008244 Hereditary gingival fibromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0403416 BXGD008282 Idiopathic crescentic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0403592 BXGD008297 Chronic rejection of renal transplant Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0424139 BXGD008520 Anxiety and fear
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0432230 BXGD008747 Langer Mesomelic Dysplasia Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0432474 BXGD008793 Klinefelter's syndrome - male with more than two X chromosomes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0432475 BXGD008794 XX males Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0564567 BXGD009486 Impulsive character (finding)
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686347 BXGD009832 Tardive Dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740302 BXGD009975 5q-syndrome Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0854248 BXGD011010 Pneumonia due to Gram negative bacteria Infections; Respiratory Tract Diseases
C0860204 BXGD011219 Cholestatic liver disease Digestive System Diseases
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0871456 BXGD011315 Subcortical lesions
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0919747 BXGD011439 Cytokine storm
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1148551 BXGD011766 X-Linked Dyskeratosis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1261473 BXGD011855 Sarcoma Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1292779 BXGD012238 Myelodysplastic Syndrome with Isolated del(5q) Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1368683 BXGD012900 Epithelioma Neoplasms
C1378511 BXGD012932 Undifferentiated leukemia
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1510885 BXGD013178 Angiogenic Switch
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519678 BXGD013243 Tumor Expansion
C1527311 BXGD013268 Brain Edema Nervous System Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1739135 BXGD013733 Progression of prostate cancer
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1802398 BXGD013758 Chromosome 5, trisomy 5q Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1846142 BXGD014785 HOYERAAL-HREIDARSSON SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Hemic and Lymphatic Diseases; Behavior and Behavior Mechanisms
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1858556 BXGD015805 OVERLAP CONNECTIVE TISSUE DISEASE Eye Diseases; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963943 BXGD016706 Atherothrombosis
C1969372 BXGD016775 Tubulointerstitial fibrosis
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363973 BXGD017121 Chronic thromboembolic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2720436 BXGD017533 Fibrosis of pleura Infections; Respiratory Tract Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2937288 BXGD018158 THYROID HORMONE RESISTANCE, GENERALIZED, AUTOSOMAL DOMINANT Endocrine System Diseases
C2937421 BXGD018162 Prostatic Hyperplasia Male Urogenital Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2981142 BXGD018210 Refractory anemia, without ringed sideroblasts, without excess blasts Hemic and Lymphatic Diseases
C2987120 BXGD018242 Intramucosal Adenocarcinoma Neoplasms
C3267003 BXGD018608 Vascular endothelial growth factor overexpression
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3489796 BXGD018952 Thyroid Hormone Resistance, Generalized, Autosomal Recessive Endocrine System Diseases
C3495798 BXGD019003 Periodontal inflammation
C3714514 BXGD019409 Infection Infections
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714760 BXGD019432 Drug-induced tardive dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
C4020969 BXGD020517 Inflammatory abnormality of the eye
C4021107 BXGD020557 Non-obstructive azoospermia Male Urogenital Diseases
C4024896 BXGD021461 Motor neuron atrophy
C4025272 BXGD021615 Peripheral arterial stenosis
C4048158 BXGD021890 Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4049279 BXGD021920 Post stroke epilepsy
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4255010 BXGD022310 Non-ST Elevated Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4285693 BXGD022446 HIV-associated neurocognitive disorder Infections; Immune System Diseases
C4285910 BXGD022462 Obstructive sleep apnea hypopnea syndrome
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4551492 BXGD023317 Micropenis
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0015497 D-phenylalanine 165.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein