adisease

Showing entry for Alexander Disease

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD006093
Disease Name	Alexander Disease
Disease CUI Id	C0270726
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05787	BXGT006385	Keratin, type II cytoskeletal 8	3856	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P55212	BXGT011112	Caspase-6	839	reviewed	Enzyme
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q14571	BXGT013485	Inositol 1,4,5-trisphosphate receptor type 2	3709	reviewed	Ion channel
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}