Showing entry for Severe hereditary factor VIII deficiency disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006343
Disease NameSevere hereditary factor VIII deficiency disease
Disease CUI IdC0272322
MeSH Codes C16   C15  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46736 BXGT010538 Lys-63-specific deubiquitinase BRCC36 79184 reviewed Enzyme
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q9BQI3 BXGT020113 Eukaryotic translation initiation factor 2-alpha kinase 1 27102 reviewed Kinase
Q9UIJ7 BXGT026029 GTP:AMP phosphotransferase AK3, mitochondrial 50808 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease