Showing entry for Adult T Acute Lymphoblastic Leukemia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006643
Disease NameAdult T Acute Lymphoblastic Leukemia
Disease CUI IdC0279592
MeSH Codes C04   C20   C15  
Disease Class NameNeoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01579 BXGT005770 Interferon gamma 3458 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P26951 BXGT009147 Interleukin-3 receptor subunit alpha 3563 reviewed Signaling
P27635 BXGT009194 60S ribosomal protein L10 6134 reviewed Nucleic acid binding
P28072 BXGT009231 Proteasome subunit beta type-6 5694 reviewed
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P51686 BXGT010881 C-C chemokine receptor type 9 10803 reviewed G-protein coupled receptor
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q15631 BXGT013585 Translin 7247 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8NBL1 BXGT018539 Protein O-glucosyltransferase 1 56983 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q6PI26 BXGT022773 Protein SHQ1 homolog 55164 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease