Showing entry for Nuclear pore complex protein Nup214


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009859
Protein NameNuclear pore complex protein Nup214
Uniport IdP35658
GeneNUP214
Gene Id8021
DomainNup214_FG
Pfam PF18617  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03013 RNA transport
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0075733 intracellular transport of virus
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0006406 mRNA export from nucleus
Biological Process GO:0006611 protein export from nucleus
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0016925 protein sumoylation
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:1900034 regulation of cellular response to heat
Biological Process GO:0060964 regulation of gene silencing by miRNA
Biological Process GO:0006110 regulation of glycolytic process
Biological Process GO:0043488 regulation of mRNA stability
Biological Process GO:0046822 regulation of nucleocytoplasmic transport
Biological Process GO:0006405 RNA export from nucleus
Biological Process GO:0006409 tRNA export from nucleus
Biological Process GO:0016032 viral process
Biological Process GO:0019083 viral transcription
molecular function GO:0005049 nuclear export signal receptor activity
molecular function GO:0008139 nuclear localization sequence binding
molecular function GO:0017056 structural constituent of nuclear pore
cellular component GO:1990876 cytoplasmic side of nuclear pore
cellular component GO:0005829 cytosol
cellular component GO:0043657 host cell
cellular component GO:0005643 nuclear pore
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1169408 ISG15 antiviral mechanism
R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1430728 Metabolism
R-HSA-159227 Transport of the SLBP independent Mature mRNA
R-HSA-159230 Transport of the SLBP Dependant Mature mRNA
R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript
R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts
R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-HSA-162587 HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-162906 HIV Infection
R-HSA-162909 Host Interactions of HIV factors
R-HSA-162909 Host Interactions of HIV factors
R-HSA-1640170 Cell Cycle
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-165054 Rev-mediated nuclear export of HIV RNA
R-HSA-168255 Influenza Infection
R-HSA-168256 Immune System
R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus
R-HSA-168276 NS1 Mediated Effects on Host Pathways
R-HSA-168325 Viral Messenger RNA Synthesis
R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery
R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein
R-HSA-176033 Interactions of Vpr with host cellular proteins
R-HSA-177243 Interactions of Rev with host cellular proteins
R-HSA-177243 Interactions of Rev with host cellular proteins
R-HSA-180746 Nuclear import of Rev protein
R-HSA-180910 Vpr-mediated nuclear import of PICs
R-HSA-191859 snRNP Assembly
R-HSA-194441 Metabolism of non-coding RNA
R-HSA-211000 Gene Silencing by RNA
R-HSA-2262752 Cellular responses to stress
R-HSA-2980766 Nuclear Envelope Breakdown
R-HSA-2990846 SUMOylation
R-HSA-2990846 SUMOylation
R-HSA-3108214 SUMOylation of DNA damage response and repair proteins
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3232142 SUMOylation of ubiquitinylation proteins
R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly
R-HSA-3371453 Regulation of HSF1-mediated heat shock response
R-HSA-3371556 Cellular response to heat stress
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-4085377 SUMOylation of SUMOylation proteins
R-HSA-450520 HuR (ELAVL1) binds and stabilizes mRNA
R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements
R-HSA-4551638 SUMOylation of chromatin organization proteins
R-HSA-4570464 SUMOylation of RNA binding proteins
R-HSA-4615885 SUMOylation of DNA replication proteins
R-HSA-4615885 SUMOylation of DNA replication proteins
R-HSA-5578749 Transcriptional regulation by small RNAs
R-HSA-5619102 SLC transporter disorders
R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-597592 Post-translational protein modification
R-HSA-6784531 tRNA processing in the nucleus
R-HSA-68875 Mitotic Prophase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-70171 Glycolysis
R-HSA-70326 Glucose metabolism
R-HSA-71387 Metabolism of carbohydrates
R-HSA-72202 Transport of Mature Transcript to Cytoplasm
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA
R-HSA-72306 tRNA processing
R-HSA-74160 Gene expression (Transcription)
R-HSA-8953854 Metabolism of RNA
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-913531 Interferon Signaling
R-HSA-9609646 HCMV Infection
R-HSA-9609690 HCMV Early Events
R-HSA-9610379 HCMV Late Events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023453 BXGD001652 L2 Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026985 BXGD001956 Myelodysplasia
C0026998 BXGD001959 Acute Myeloid Leukemia, M1 Neoplasms
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0220615 BXGD004298 Adult Acute Myeloblastic Leukemia Neoplasms
C0220621 BXGD004300 Childhood Acute Myeloid Leukemia Neoplasms
C0232466 BXGD004543 Feeding difficulties
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0266617 BXGD005700 Congenital anomaly of face Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0279592 BXGD006643 Adult T Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0280141 BXGD006716 Acute Undifferentiated Leukemia
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0456070 BXGD008863 Growth delay
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0544886 BXGD009319 Somatic mutation
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0740279 BXGD009973 Cerebellar atrophy
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1836830 BXGD014165 Developmental regression Mental Disorders
C1850456 BXGD015146 Progressive microcephaly
C1850719 BXGD015172 Recurrent encephalopathy Nervous System Diseases
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1879321 BXGD016572 Acute Myeloid Leukemia (AML-M2) Neoplasms
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C4277639 BXGD022375 Acute Febrile Encephalopathy Nervous System Diseases
C4288892 BXGD022487 Infant Acute Undifferentiated Leukemia
C4553743 BXGD023548 Spasticity, CTCAE
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein