protein

Showing entry for Interleukin-7 receptor subunit alpha

General Target Information
BXGT Id	BXGT008269
Protein Name	Interleukin-7 receptor subunit alpha
Uniport Id	P16871
Gene	IL7R
Gene Id	3575
Domain	fn3; FN3_7
Pfam	PF00041 PF18447
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
3. Environmental Information Processing	3.3 Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction
3. Environmental Information Processing	3.2 Signal transduction	hsa04068	FoxO signaling pathway
3. Environmental Information Processing	3.2 Signal transduction	hsa04151	PI3K-Akt signaling pathway
3. Environmental Information Processing	3.2 Signal transduction	hsa04630	Jak-STAT signaling pathway
5. Organismal Systems	5.1 Immune system	hsa04640	Hematopoietic cell lineage
6. Human Diseases	6.1 Cancers: Overview	hsa05200	Pathways in cancer
6. Human Diseases	6.3 Immune diseases	hsa05340	Primary immunodeficiency

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0042100	B cell proliferation
Biological Process	GO:0000902	cell morphogenesis
Biological Process	GO:0007166	cell surface receptor signaling pathway
Biological Process	GO:0050830	defense response to Gram-positive bacterium
Biological Process	GO:0048872	homeostasis of number of cells
Biological Process	GO:0006955	immune response
Biological Process	GO:0002377	immunoglobulin production
Biological Process	GO:0038111	interleukin-7-mediated signaling pathway
Biological Process	GO:0048535	lymph node development
Biological Process	GO:0061024	membrane organization
Biological Process	GO:0070233	negative regulation of T cell apoptotic process
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity
Biological Process	GO:0008284	positive regulation of cell population proliferation
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus
Biological Process	GO:0008361	regulation of cell size
Biological Process	GO:0000018	regulation of DNA recombination
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0030217	T cell differentiation
molecular function	GO:0003823	antigen binding
molecular function	GO:0004896	cytokine receptor activity
molecular function	GO:0004917	interleukin-7 receptor activity
cellular component	GO:0030665	clathrin-coated vesicle membrane
cellular component	GO:0009897	external side of plasma membrane
cellular component	GO:0005576	extracellular region
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-1266695	Interleukin-7 signaling
R-HSA-1266695	Interleukin-7 signaling
R-HSA-1280215	Cytokine Signaling in Immune system
R-HSA-1280215	Cytokine Signaling in Immune system
R-HSA-168256	Immune System
R-HSA-168256	Immune System
R-HSA-199991	Membrane Trafficking
R-HSA-449147	Signaling by Interleukins
R-HSA-449147	Signaling by Interleukins
R-HSA-5653656	Vesicle-mediated transport
R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis
R-HSA-8856828	Clathrin-mediated endocytosis

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001175	BXGD000029	Acquired Immunodeficiency Syndrome	Infections; Immune System Diseases
C0001339	BXGD000041	Acute pancreatitis	Digestive System Diseases
C0002170	BXGD000105	Alopecia	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002871	BXGD000132	Anemia	Hemic and Lymphatic Diseases
C0003864	BXGD000231	Arthritis	Musculoskeletal Diseases
C0003872	BXGD000235	Arthritis, Psoriatic	Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0004364	BXGD000270	Autoimmune Diseases	Immune System Diseases
C0004368	BXGD000271	Autoimmune state
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007193	BXGD000451	Cardiomyopathy, Dilated	Cardiovascular Diseases
C0007621	BXGD000468	Neoplastic Cell Transformation	Pathological Conditions, Signs and Symptoms; Neoplasms
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008031	BXGD000511	Chest Pain	Pathological Conditions, Signs and Symptoms
C0008312	BXGD000527	Primary biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010346	BXGD000664	Crohn Disease	Digestive System Diseases
C0010823	BXGD000690	Cytomegalovirus Infections	Infections
C0011303	BXGD000712	Demyelinating Diseases	Nervous System Diseases
C0011603	BXGD000734	Dermatitis	Skin and Connective Tissue Diseases
C0011606	BXGD000735	Exfoliative dermatitis	Skin and Connective Tissue Diseases
C0011847	BXGD000749	Diabetes	Endocrine System Diseases
C0011849	BXGD000751	Diabetes Mellitus	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011991	BXGD000766	Diarrhea	Pathological Conditions, Signs and Symptoms
C0013595	BXGD000858	Eczema	Skin and Connective Tissue Diseases
C0013604	BXGD000859	Edema	Pathological Conditions, Signs and Symptoms
C0014070	BXGD000887	Encephalomyelitis	Infections; Nervous System Diseases
C0014175	BXGD000904	Endometriosis	Female Urogenital Diseases and Pregnancy Complications
C0014457	BXGD000915	Eosinophilia	Hemic and Lymphatic Diseases
C0014859	BXGD000961	Esophageal Neoplasms	Digestive System Diseases; Neoplasms
C0015544	BXGD001003	Failure to Thrive	Pathological Conditions, Signs and Symptoms
C0015967	BXGD001030	Fever	Pathological Conditions, Signs and Symptoms
C0018133	BXGD001176	Graft-vs-Host Disease	Immune System Diseases
C0019163	BXGD001295	Hepatitis B	Digestive System Diseases; Infections
C0019196	BXGD001301	Hepatitis C	Digestive System Diseases; Infections
C0019209	BXGD001305	Hepatomegaly	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019214	BXGD001307	Hepatosplenomegaly	Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0019340	BXGD001321	Herpes NOS	Infections
C0019693	BXGD001346	HIV Infections	Infections; Immune System Diseases
C0020456	BXGD001392	Hyperglycemia	Nutritional and Metabolic Diseases
C0020676	BXGD001462	Hypothyroidism	Endocrine System Diseases
C0021400	BXGD001504	Influenza	Infections; Respiratory Tract Diseases
C0022658	BXGD001570	Kidney Diseases	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418	BXGD001642	leukemia	Neoplasms
C0023434	BXGD001643	Chronic Lymphocytic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449	BXGD001650	Acute lymphocytic leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452	BXGD001651	Childhood Acute Lymphoblastic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465	BXGD001656	Acute monocytic leukemia	Neoplasms
C0023467	BXGD001658	Leukemia, Myelocytic, Acute	Neoplasms
C0023487	BXGD001669	Acute Promyelocytic Leukemia	Neoplasms
C0023508	BXGD001675	White Blood Cell Count procedure
C0023787	BXGD001698	Lipodystrophy	Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0023892	BXGD001715	Biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893	BXGD001716	Liver Cirrhosis, Experimental	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895	BXGD001717	Liver diseases	Digestive System Diseases
C0024138	BXGD001738	Lupus Erythematosus, Discoid	Skin and Connective Tissue Diseases
C0024141	BXGD001740	Lupus Erythematosus, Systemic	Skin and Connective Tissue Diseases; Immune System Diseases
C0024266	BXGD001754	Lymphocytic Choriomeningitis	Infections; Nervous System Diseases
C0024282	BXGD001755	Lymphocytosis	Hemic and Lymphatic Diseases
C0024299	BXGD001758	Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024301	BXGD001759	Lymphoma, Follicular	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305	BXGD001763	Lymphoma, Non-Hodgkin	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312	BXGD001766	Lymphopenia	Immune System Diseases; Hemic and Lymphatic Diseases
C0024530	BXGD001783	Malaria	Infections
C0024535	BXGD001785	Malaria, Falciparum	Infections
C0025007	BXGD001821	Measles	Infections
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases
C0026896	BXGD001946	Myasthenia Gravis	Neoplasms; Immune System Diseases; Nervous System Diseases
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027697	BXGD002022	Nephritis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027726	BXGD002030	Nephrotic Syndrome	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0027873	BXGD002054	Neuromyelitis Optica	Eye Diseases; Immune System Diseases; Nervous System Diseases
C0027947	BXGD002061	Neutropenia	Hemic and Lymphatic Diseases
C0029118	BXGD002111	Opportunistic Infections	Infections
C0029408	BXGD002137	Degenerative polyarthritis	Musculoskeletal Diseases
C0029882	BXGD002177	Otitis Media	Otorhinolaryngologic Diseases
C0030354	BXGD002214	Papilloma	Neoplasms
C0032285	BXGD002344	Pneumonia	Infections; Respiratory Tract Diseases
C0033774	BXGD002419	Pruritus	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0034069	BXGD002458	Pulmonary Fibrosis	Respiratory Tract Diseases
C0035222	BXGD002513	Respiratory Distress Syndrome, Adult	Respiratory Tract Diseases
C0035242	BXGD002521	Respiratory Tract Diseases	Respiratory Tract Diseases
C0035243	BXGD002522	Respiratory Tract Infections	Infections; Respiratory Tract Diseases
C0035920	BXGD002570	Rubella	Infections
C0036202	BXGD002581	Sarcoidosis	Hemic and Lymphatic Diseases
C0036421	BXGD002613	Systemic Scleroderma	Skin and Connective Tissue Diseases
C0036690	BXGD002632	Septicemia	Pathological Conditions, Signs and Symptoms; Infections
C0038002	BXGD002723	Splenomegaly	Pathological Conditions, Signs and Symptoms
C0038013	BXGD002725	Ankylosing spondylitis	Musculoskeletal Diseases
C0040147	BXGD002847	Thyroiditis	Endocrine System Diseases
C0040580	BXGD002877	Tracheal Diseases	Respiratory Tract Diseases
C0041296	BXGD002903	Tuberculosis	Infections
C0042749	BXGD002998	Viremia	Pathological Conditions, Signs and Symptoms; Infections
C0042769	BXGD002999	Virus Diseases	Infections
C0079731	BXGD003087	B-Cell Lymphomas	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772	BXGD003099	T-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085110	BXGD003126	Severe Combined Immunodeficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0085669	BXGD003233	Acute leukemia	Pathological Conditions, Signs and Symptoms; Neoplasms
C0149745	BXGD003356	Oral Ulcer	Stomatognathic Diseases
C0149958	BXGD003395	Complex partial seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151517	BXGD003431	Complete atrioventricular block	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151908	BXGD003502	Dry skin	Skin and Connective Tissue Diseases
C0152013	BXGD003516	Adenocarcinoma of lung (disorder)	Neoplasms
C0152018	BXGD003518	Esophageal carcinoma	Digestive System Diseases; Neoplasms
C0153014	BXGD003612	Non-arthropod borne lymphocytic choriomeningitis	Infections; Nervous System Diseases
C0153690	BXGD003684	Secondary malignant neoplasm of bone	Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0175697	BXGD004004	Van der Woude syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0220615	BXGD004298	Adult Acute Myeloblastic Leukemia	Neoplasms
C0221277	BXGD004434	Atypical lymphocyte
C0238065	BXGD004869	Secondary Biliary Cholangitis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0239946	BXGD005010	Fibrosis, Liver	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0241165	BXGD005083	Thick skin
C0241910	BXGD005123	Autoimmune Chronic Hepatitis	Digestive System Diseases; Immune System Diseases
C0242350	BXGD005154	Erectile dysfunction	Male Urogenital Diseases; Mental Disorders
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0242596	BXGD005181	Neoplasm, Residual	Pathological Conditions, Signs and Symptoms; Neoplasms
C0242647	BXGD005184	Mucosa-Associated Lymphoid Tissue Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0243026	BXGD005210	Sepsis	Pathological Conditions, Signs and Symptoms; Infections
C0265987	BXGD005598	Nevus comedonicus	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C0266815	BXGD005717	Cow milk allergy	Digestive System Diseases; Immune System Diseases
C0269102	BXGD006053	Endometrioma	Female Urogenital Diseases and Pregnancy Complications
C0275518	BXGD006375	Acute infectious disease	Pathological Conditions, Signs and Symptoms; Infections
C0276199	BXGD006406	Canarypox (disorder)
C0279583	BXGD006640	Childhood T Acute Lymphoblastic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279592	BXGD006643	Adult T Acute Lymphoblastic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279626	BXGD006657	Squamous cell carcinoma of esophagus	Digestive System Diseases; Neoplasms
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0339143	BXGD007226	Thyroid associated opthalmopathies	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0340288	BXGD007316	Stable angina	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0342288	BXGD007456	Insulin-dependent diabetes mellitus secretory diarrhea syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0376545	BXGD008002	Hematologic Neoplasms	Neoplasms; Hemic and Lymphatic Diseases
C0398650	BXGD008212	Immune thrombocytopenic purpura	Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0398686	BXGD008215	Primary immune deficiency disorder	Immune System Diseases
C0401151	BXGD008274	Chronic diarrhea	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0424295	BXGD008524	Hyperactive behavior	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0456103	BXGD008866	Sepsis of the newborn	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections
C0497156	BXGD009053	Lymphadenopathy	Hemic and Lymphatic Diseases
C0520680	BXGD009102	Sleep Apnea, Central	Respiratory Tract Diseases; Nervous System Diseases
C0524851	BXGD009246	Neurodegenerative Disorders	Nervous System Diseases
C0524909	BXGD009247	Hepatitis B, Chronic	Digestive System Diseases; Infections
C0524910	BXGD009248	Hepatitis C, Chronic	Digestive System Diseases; Infections
C0546837	BXGD009343	Malignant neoplasm of esophagus	Digestive System Diseases; Neoplasms
C0549463	BXGD009382	X-Linked Lymphoproliferative Disorder	Immune System Diseases; Hemic and Lymphatic Diseases
C0581381	BXGD009567	Recurrent upper respiratory tract infection	Infections; Respiratory Tract Diseases
C0595936	BXGD009628	Aqueous Humor Disorders	Eye Diseases
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766	BXGD009669	Leukemogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0684249	BXGD009790	Carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C0746104	BXGD010137	lung disease granulomatous
C0751039	BXGD010302	Cockayne Syndrome, Type I	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0751324	BXGD010388	Multiple Sclerosis, Acute Fulminating	Immune System Diseases; Nervous System Diseases
C0751606	BXGD010523	Adult Acute Lymphocytic Leukemia
C0751688	BXGD010551	Malignant Squamous Cell Neoplasm	Neoplasms
C0751964	BXGD010655	Multiple Sclerosis, Primary Progressive	Immune System Diseases; Nervous System Diseases
C0751967	BXGD010657	Multiple Sclerosis, Relapsing-Remitting	Immune System Diseases; Nervous System Diseases
C0853112	BXGD010967	Chronic infection with HIV
C0855095	BXGD011071	Small Lymphocytic Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0856825	BXGD011118	Acute GVH disease	Immune System Diseases
C0867389	BXGD011300	Chronic graft-versus-host disease	Immune System Diseases
C0877024	BXGD011330	Schimke immunoosseous dysplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Respiratory Tract Diseases; Immune System Diseases; Cardiovascular Diseases
C0948008	BXGD011499	Ischemic stroke	Nervous System Diseases; Cardiovascular Diseases
C0948089	BXGD011504	Acute Coronary Syndrome	Cardiovascular Diseases
C0949690	BXGD011584	Spondylarthritis	Musculoskeletal Diseases
C1141957	BXGD011726	HIV disease progression
C1142553	BXGD011761	Primary HIV infection	Infections; Immune System Diseases
C1272352	BXGD012013	Deficiency of vitamin D3	Nutritional and Metabolic Diseases
C1279481	BXGD012123	X-Linked Combined Immunodeficiency Diseases	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C1280433	BXGD012125	Lipoatrophy	Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C1292769	BXGD012230	Precursor B-cell lymphoblastic leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1306460	BXGD012362	Primary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C1332977	BXGD012569	Childhood Leukemia	Neoplasms
C1367654	BXGD012886	Marginal Zone B-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1449563	BXGD013086	Cardiomyopathy, Familial Idiopathic	Cardiovascular Diseases
C1527304	BXGD013266	Allergic Reaction	Immune System Diseases
C1527336	BXGD013271	Sjogren's Syndrome	Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1533172	BXGD013311	Infantile nystagmus syndrome	Eye Diseases; Nervous System Diseases
C1611743	BXGD013456	Familial (FPAH)
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1832323	BXGD013827	Failure to thrive secondary to recurrent infections
C1832324	BXGD013828	Recurrent opportunistic infections	Infections
C1836195	BXGD014094	Short toe
C1837028	BXGD014187	Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C1837066	BXGD014190	Recurrent viral infection	Infections
C1839304	BXGD014365	Decreased proportion of CD4-positive T cells	Immune System Diseases; Hemic and Lymphatic Diseases
C1839305	BXGD014366	Decreased proportion of CD8-positive T cells	Immune System Diseases; Hemic and Lymphatic Diseases
C1841972	BXGD014484	Glucocorticoid Receptor Deficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1842714	BXGD014535	Desquamation of skin soon after birth
C1855472	BXGD015499	Acute lymphoblastic leukemia with lymphomatous features	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1860128	BXGD015957	Recurrent candida infections
C1956346	BXGD016627	Coronary Artery Disease	Cardiovascular Diseases
C1961099	BXGD016672	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102	BXGD016673	Precursor Cell Lymphoblastic Leukemia Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963094	BXGD016681	Dry Skin, CTCAE
C2363741	BXGD017100	HIV-1 infection
C2607914	BXGD017148	Allergic rhinitis (disorder)	Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2700553	BXGD017472	Omenn Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C2745900	BXGD017568	Promyelocytic leukemia
C2931322	BXGD018003	T-Lymphocytopenia	Immune System Diseases; Hemic and Lymphatic Diseases
C2939419	BXGD018178	Secondary Neoplasm	Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280	BXGD018223	Blood Protein Measurement
C3163798	BXGD018516	Recurrent lower respiratory tract infection
C3495559	BXGD018994	Juvenile arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714757	BXGD019430	Juvenile rheumatoid arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3809768	BXGD019610	IMMUNODEFICIENCY 13
C3854222	BXGD019826	Human immunodeficiency virus (HIV) II infection category B1
C3875321	BXGD019874	Inflammatory dermatosis	Skin and Connective Tissue Diseases
C4021956	BXGD020839	Aplasia/Hypoplasia of the eyebrow
C4025814	BXGD021806	Abnormality of the metaphysis
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049273	BXGD021919	Systemic immune activation
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms
C4476830	BXGD022877	Psoriasiform lesion
C4477053	BXGD022911	Decreased proportion of CD3-positive T cells	Immune System Diseases; Hemic and Lymphatic Diseases
C4505456	BXGD022964	HIV Coinfection	Infections; Immune System Diseases
C4531166	BXGD023200	Decreased lymphocyte proliferation in response to mitogen
C4551595	BXGD023367	Biliary Cirrhosis, Primary, 1	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C4552766	BXGD023523	Miscarriage	Female Urogenital Diseases and Pregnancy Complications
C4721555	BXGD023755	Autoimmune hepatitis	Digestive System Diseases
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}