Showing entry for Forkhead box protein O3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004599
Protein NameForkhead box protein O3
Uniport IdO43524
GeneFOXO3
Gene Id2309
DomainForkhead; FOXO-TAD; FOXO_KIX_bdg
Pfam PF00250   PF16676   PF16675  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
5. Organismal Systems 5.9 Aging hsa04211 Longevity regulating pathway
5. Organismal Systems 5.9 Aging hsa04213 Longevity regulating pathway - multiple species
4. Cellular Processes 4.2 Cell growth and death hsa04218 Cellular senescence
5. Organismal Systems 5.6 Nervous system hsa04722 Neurotrophin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04917 Prolactin signaling pathway
6. Human Diseases 6.2 Cancers: Specific types hsa05213 Endometrial cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05223 Non-small cell lung cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0001547 antral ovarian follicle growth
Biological Process GO:0048854 brain morphogenesis
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0071386 cellular response to corticosterone stimulus
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0030330 DNA damage response, signal transduction by p53 class mediator
Biological Process GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0001544 initiation of primordial ovarian follicle growth
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:0006390 mitochondrial transcription
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0045665 negative regulation of neuron differentiation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0097150 neuronal stem cell population maintenance
Biological Process GO:0001556 oocyte maturation
Biological Process GO:0001542 ovulation from ovarian follicle
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010508 positive regulation of autophagy
Biological Process GO:2000353 positive regulation of endothelial cell apoptotic process
Biological Process GO:0045648 positive regulation of erythrocyte differentiation
Biological Process GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
Biological Process GO:0014737 positive regulation of muscle atrophy
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
Biological Process GO:1903428 positive regulation of reactive oxygen species biosynthetic process
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:2000177 regulation of neural precursor cell proliferation
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0006417 regulation of translation
Biological Process GO:0071548 response to dexamethasone
Biological Process GO:0042493 response to drug
Biological Process GO:0070542 response to fatty acid
Biological Process GO:0042594 response to starvation
Biological Process GO:1990785 response to water-immersion restraint stress
Biological Process GO:0033209 tumor necrosis factor-mediated signaling pathway
molecular function GO:0008013 beta-catenin binding
molecular function GO:0031490 chromatin DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0034246 mitochondrial sequence-specific DNA-binding transcription factor activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0001221 transcription cofactor binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-1181150 Signaling by NODAL
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-168256 Immune System
R-HSA-198693 AKT phosphorylates targets in the nucleus
R-HSA-212436 Generic Transcription Pathway
R-HSA-212436 Generic Transcription Pathway
R-HSA-2219528 PI3K/AKT Signaling in Cancer
R-HSA-449147 Signaling by Interleukins
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-74160 Gene expression (Transcription)
R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
R-HSA-8863678 Neurodegenerative Diseases
R-HSA-8863678 Neurodegenerative Diseases
R-HSA-8878159 Transcriptional regulation by RUNX3
R-HSA-8939211 ESR-mediated signaling
R-HSA-8952158 RUNX3 regulates BCL2L11 (BIM) transcription
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006931 Signaling by Nuclear Receptors
R-HSA-9009391 Extra-nuclear estrogen signaling
R-HSA-9614085 FOXO-mediated transcription
R-HSA-9614085 FOXO-mediated transcription
R-HSA-9614399 Regulation of localization of FOXO transcription factors
R-HSA-9614657 FOXO-mediated transcription of cell death genes
R-HSA-9614657 FOXO-mediated transcription of cell death genes
R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation
R-HSA-9617828 FOXO-mediated transcription of cell cycle genes
R-HSA-9617828 FOXO-mediated transcription of cell cycle genes
R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling
R-HSA-9645723 Diseases of programmed cell death
R-HSA-9645723 Diseases of programmed cell death
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001144 BXGD000028 Acne Vulgaris Skin and Connective Tissue Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001420 BXGD000051 Papillary adenocarcinoma Neoplasms
C0002152 BXGD000104 Alloxan Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0005890 BXGD000345 Body Height
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010246 BXGD000656 Coxsackievirus Infections Infections
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014072 BXGD000888 Experimental Autoimmune Encephalomyelitis Immune System Diseases; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018206 BXGD001186 granulosa cell tumor Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020507 BXGD001413 Hyperplasia Pathological Conditions, Signs and Symptoms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023448 BXGD001649 Lymphoid leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023524 BXGD001681 Leukoencephalopathy, Progressive Multifocal Infections; Nervous System Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024266 BXGD001754 Lymphocytic Choriomeningitis Infections; Nervous System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024535 BXGD001785 Malaria, Falciparum Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027070 BXGD001967 Myoepithelioma Neoplasms
C0027339 BXGD001981 Nail Diseases Skin and Connective Tissue Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031029 BXGD002271 Periapical Granuloma Stomatognathic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034103 BXGD002464 Pulpitis Stomatognathic Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0038433 BXGD002754 Streptozotocin Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039538 BXGD002819 Teratoma Neoplasms
C0039984 BXGD002832 Thoracic Outlet Syndrome Nervous System Diseases; Cardiovascular Diseases
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042834 BXGD003004 Vital capacity
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0149696 BXGD003347 Food intolerance (disorder) Pathological Conditions, Signs and Symptoms
C0149721 BXGD003349 Left Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151332 BXGD003415 Active tuberculosis Infections
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0153014 BXGD003612 Non-arthropod borne lymphocytic choriomeningitis Infections; Nervous System Diseases
C0153349 BXGD003621 Malignant neoplasm of tongue Neoplasms; Stomatognathic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0158266 BXGD003878 Intervertebral Disc Degeneration Musculoskeletal Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0162835 BXGD003989 Hypopigmentation disorder Skin and Connective Tissue Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0178879 BXGD004038 Urinary tract obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0206161 BXGD004167 Reticulocyte count (procedure)
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0231341 BXGD004492 Premature aging syndrome Pathological Conditions, Signs and Symptoms
C0232939 BXGD004568 Primary physiologic amenorrhea Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0237020 BXGD004844 Dermoid cyst of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0238301 BXGD004909 Cancer of Nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238478 BXGD004940 Transient erythroblastopenia of childhood Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0243066 BXGD005213 Atresia
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0267924 BXGD005791 Suppurative cholangitis Digestive System Diseases; Infections
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0276138 BXGD006403 Viral myocarditis Infections; Cardiovascular Diseases
C0276447 BXGD006425 Rhinovirus infection Infections
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279583 BXGD006640 Childhood T Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279592 BXGD006643 Adult T Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279751 BXGD006694 Adenoid cystic carcinoma of salivary gland Neoplasms; Stomatognathic Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280216 BXGD006719 stage, neuroblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333519 BXGD006958 Caries (morphologic abnormality) Pathological Conditions, Signs and Symptoms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342527 BXGD007496 Deficiency of testosterone biosynthesis Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0393591 BXGD008102 AICARDI-GOUTIERES SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Nervous System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424678 BXGD008537 Lean body mass
C0455829 BXGD008859 Waist Circumference
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0562350 BXGD009476 Hip circumference
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596887 BXGD009648 mathematical ability
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677936 BXGD009737 Refractory cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0679362 BXGD009767 Tuberculosis, extrapulmonary Infections
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0699893 BXGD009871 Skin carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0747102 BXGD010159 Ovarian failure Endocrine System Diseases
C0747845 BXGD010184 early pregnancy
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0752308 BXGD010715 Hypoxia-Ischemia, Brain Nervous System Diseases; Cardiovascular Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0853112 BXGD010967 Chronic infection with HIV
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0854917 BXGD011050 Rhabdoid Tumor of the Kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0856742 BXGD011111 Post MI Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0878500 BXGD011365 Intraepithelial Neoplasia Neoplasms
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0917805 BXGD011414 Transient Cerebral Ischemia Nervous System Diseases; Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920646 BXGD011471 Ischemia of kidney Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1266101 BXGD011960 Thymic epithelial tumor Neoplasms; Hemic and Lymphatic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332182 BXGD012495 Adult Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332942 BXGD012558 Childhood Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1337013 BXGD012876 Differentiated Thyroid Gland Carcinoma
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1391732 BXGD012971 Cancer cachexia
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519678 BXGD013243 Tumor Expansion
C1527303 BXGD013265 Chronic Airflow Obstruction Respiratory Tract Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1609538 BXGD013444 Latent Tuberculosis Infections
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1654637 BXGD013484 androgen independent prostate cancer
C1692871 BXGD013494 Inflammatory polyarthritis
C1739135 BXGD013733 Progression of prostate cancer
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1840264 BXGD014439 IMMUNE SUPPRESSION
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1862382 BXGD016125 SVEINSSON CHORIORETINAL ATROPHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347747 BXGD017040 Adult Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2363741 BXGD017100 HIV-1 infection
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2732697 BXGD017557 Autoimmune inflammation of skeletal muscle Musculoskeletal Diseases; Immune System Diseases; Nervous System Diseases
C2747816 BXGD017577 Complicated malaria Infections
C2873756 BXGD017818 Severe beta thalassemia
C2931367 BXGD018010 Thyroid cancer, follicular Neoplasms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3272802 BXGD018631 Hamartomatous polyposis Pathological Conditions, Signs and Symptoms; Neoplasms
C3281200 BXGD018888 LEUKOENCEPHALOPATHY, BRAIN CALCIFICATIONS, AND CYSTS Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Nervous System Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
C3830518 BXGD019753 Diabetic embryopathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049446 BXGD021933 Neointimal hyperplasia
C4049938 BXGD021956 Physical Activity Measurement
C4075512 BXGD022069 Flap necrosis
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4087397 BXGD022146 Mammary gland tumor
C4285693 BXGD022446 HIV-associated neurocognitive disorder Infections; Immune System Diseases
C4288891 BXGD022486 Infant T Acute Lymphoblastic Leukemia
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722172 BXGD023791 Primary differentiated carcinoma of thyroid gland
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001767 (E)-Resveratrol 228.25
BXGC0007668 (+)-Syringaresinol 418.44
BXGC0042753 (-)-Syringaresinol 418.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein