Showing entry for Hereditary non-polyposis colorectal cancer syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011647
Disease NameHereditary non-polyposis colorectal cancer syndrome
Disease CUI IdC1112155
MeSH Codes   
Disease Class Name
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630  
Disease Ontology Class Namegenetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P35221 BXGT009798 Catenin alpha-1 1495 reviewed Cellular structure
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
Q12913 BXGT013279 Receptor-type tyrosine-protein phosphatase eta 5795 reviewed Enzyme
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13426 BXGT013353 DNA repair protein XRCC4 7518 reviewed
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q99728 BXGT019956 BRCA1-associated RING domain protein 1 580 reviewed
Q9UQ84 BXGT021807 Exonuclease 1 9156 reviewed Enzyme
Q9Y2M0 BXGT022241 Fanconi-associated nuclease 1 22909 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease