Showing entry for TNF receptor-associated periodic fever syndrome (TRAPS)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012062
Disease NameTNF receptor-associated periodic fever syndrome (TRAPS)
Disease CUI IdC1275126
MeSH Codes C23   C16   C17  
Disease Class NamePathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630  
Disease Ontology Class Namegenetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15553 BXGT004181 Pyrin 4210 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13938 BXGT013405 Calcyphosin 828 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease