Showing entry for Steroid 17-alpha-hydroxylase/17,20 lyase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006313
Protein NameSteroid 17-alpha-hydroxylase/17,20 lyase
Uniport IdP05093
GeneCYP17A1
Gene Id1586
Domainp450
Pfam PF00067  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00140 Steroid hormone biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.2 Endocrine system hsa04913 Ovarian steroidogenesis
5. Organismal Systems 5.2 Endocrine system hsa04917 Prolactin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04927 Cortisol synthesis and secretion
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04934 Cushing syndrome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006702 androgen biosynthetic process
Biological Process GO:0006704 glucocorticoid biosynthetic process
Biological Process GO:0042446 hormone biosynthetic process
Biological Process GO:0042448 progesterone metabolic process
Biological Process GO:0007548 sex differentiation
Biological Process GO:0006694 steroid biosynthetic process
Biological Process GO:0008202 steroid metabolic process
molecular function GO:0047442 17-alpha-hydroxyprogesterone aldolase activity
molecular function GO:0020037 heme binding
molecular function GO:0005506 iron ion binding
molecular function GO:0019825 oxygen binding
molecular function GO:0004508 steroid 17-alpha-monooxygenase activity
cellular component GO:0030424 axon
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0043025 neuronal cell body
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-193048 Androgen biosynthesis
R-HSA-194002 Glucocorticoid biosynthesis
R-HSA-196071 Metabolism of steroid hormones
R-HSA-556833 Metabolism of lipids
R-HSA-5579028 Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
R-HSA-5579029 Metabolic disorders of biological oxidation enzymes
R-HSA-5668914 Diseases of metabolism
R-HSA-8957322 Metabolism of steroids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001144 BXGD000028 Acne Vulgaris Skin and Connective Tissue Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0001624 BXGD000067 Adrenal Gland Neoplasms Neoplasms; Endocrine System Diseases
C0001627 BXGD000068 Congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0004775 BXGD000290 Bartter Disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0005823 BXGD000339 Blood Pressure
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006144 BXGD000375 Breast Cyst Neoplasms; Skin and Connective Tissue Diseases
C0006145 BXGD000376 Breast Diseases Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007104 BXGD000427 Female Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009405 BXGD000607 Hereditary Nonpolyposis Colorectal Neoplasms Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C0009777 BXGD000630 Conn Adenoma Neoplasms; Endocrine System Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010093 BXGD000652 Corpus Luteum Cyst Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013390 BXGD000828 Dysmenorrhea Pathological Conditions, Signs and Symptoms
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014130 BXGD000899 Endocrine System Diseases Endocrine System Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014173 BXGD000903 Endometrial Hyperplasia Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016034 BXGD001034 Breast Fibrocystic Disease Skin and Connective Tissue Diseases
C0016722 BXGD001075 Frigidity Mental Disorders
C0016724 BXGD001076 Froehlich's Syndrome Nervous System Diseases
C0016977 BXGD001086 Gall Bladder Diseases Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018206 BXGD001186 granulosa cell tumor Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0018418 BXGD001192 Gynecomastia Skin and Connective Tissue Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019360 BXGD001327 Herpes zoster disease Infections
C0020428 BXGD001377 Hyperaldosteronism Endocrine System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020461 BXGD001395 Hyperkalemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020540 BXGD001423 Malignant Hypertension Cardiovascular Diseases
C0020594 BXGD001437 Hypoactive Sexual Desire Disorder Mental Disorders
C0020595 BXGD001438 Hypoaldosteronism Endocrine System Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0020621 BXGD001449 Hypokalemia Nutritional and Metabolic Diseases
C0020635 BXGD001455 Hypopituitarism Nervous System Diseases; Endocrine System Diseases
C0020651 BXGD001460 Hypotension, Orthostatic Nervous System Diseases; Cardiovascular Diseases
C0021167 BXGD001487 Incontinence Nervous System Diseases
C0021359 BXGD001498 Infertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0021361 BXGD001499 Female infertility Female Urogenital Diseases and Pregnancy Complications
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028949 BXGD002100 Oligomenorrhea Pathological Conditions, Signs and Symptoms
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0029261 BXGD002126 Orgasmic Disorder Mental Disorders
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029927 BXGD002182 Ovarian Cysts Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032796 BXGD002372 Postpartum Amenorrhea Pathological Conditions, Signs and Symptoms
C0033575 BXGD002407 Prostatic Diseases Male Urogenital Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033804 BXGD002426 Pseudohermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0033953 BXGD002445 Psychosexual Disorders Mental Disorders
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0036631 BXGD002626 Seminoma Neoplasms
C0036875 BXGD002640 Disorders of Sex Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0036902 BXGD002641 Sexual Arousal Disorder Mental Disorders
C0038279 BXGD002744 Sterility, Postpartum Female Urogenital Diseases and Pregnancy Complications
C0038870 BXGD002782 Neuralgia, Supraorbital Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042656 BXGD002995 Neuralgia, Vidian Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085570 BXGD003186 Hypokalemic alkalosis Nutritional and Metabolic Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0149952 BXGD003393 Torsion of ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151639 BXGD003452 Decreased fertility in females Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151640 BXGD003453 Decreased fertility in males Male Urogenital Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0206081 BXGD004152 Hyperandrogenism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0206635 BXGD004200 Myelolipoma Neoplasms
C0206650 BXGD004214 Fibroadenoma Neoplasms
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0232939 BXGD004568 Primary physiologic amenorrhea Pathological Conditions, Signs and Symptoms
C0234247 BXGD004642 Neuralgia, Atypical Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234249 BXGD004643 Neuralgia, Stump Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235653 BXGD004762 Malignant neoplasm of female breast Neoplasms; Skin and Connective Tissue Diseases
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236075 BXGD004810 Menopausal symptom
C0238033 BXGD004861 Carcinoma of Male Breast Neoplasms; Skin and Connective Tissue Diseases
C0238339 BXGD004914 Hereditary pancreatitis Digestive System Diseases
C0238395 BXGD004922 Male Pseudohermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0241011 BXGD005073 Low serum estradiol levels
C0241355 BXGD005092 Small testicle
C0242341 BXGD005151 Sexual Infantilism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0242342 BXGD005152 Sheehan Syndrome Nervous System Diseases; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242787 BXGD005195 Malignant neoplasm of male breast Neoplasms; Skin and Connective Tissue Diseases; Endocrine System Diseases
C0266362 BXGD005657 Ambiguous Genitalia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0266399 BXGD005663 Infantile uterus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268285 BXGD005883 Adrenal hyperplasia, congenital, type 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0268287 BXGD005884 Deficiency of steroid 21-monooxygenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0271623 BXGD006222 Hypogonadotropic hypogonadism Endocrine System Diseases
C0272139 BXGD006309 Erythrocytosis due to low atmospheric pressure Hemic and Lymphatic Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0280280 BXGD006731 stage, prostate cancer Neoplasms; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0302280 BXGD006836 Adrenogenital Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0334524 BXGD007102 Mixed Germ Cell Tumor Neoplasms
C0341858 BXGD007425 Endometriosis of uterus Female Urogenital Diseases and Pregnancy Complications
C0341869 BXGD007427 Subfertility, Female Female Urogenital Diseases and Pregnancy Complications
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342513 BXGD007494 Idiopathic hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0342527 BXGD007496 Deficiency of testosterone biosynthesis Endocrine System Diseases
C0345309 BXGD007725 Hypoplasia of vagina Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346153 BXGD007781 Breast Cancer, Familial Neoplasms; Skin and Connective Tissue Diseases
C0346629 BXGD007831 Malignant neoplasm of large intestine Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0405580 BXGD008325 Adrenal cortical hypofunction Endocrine System Diseases
C0423711 BXGD008498 Neuralgia, Perineal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0423712 BXGD008499 Neuralgia, Iliohypogastric Nerve Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0428883 BXGD008639 Diastolic blood pressure
C0428886 BXGD008640 Mean blood pressure
C0432470 BXGD008792 46, XY female Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0455829 BXGD008859 Waist Circumference
C0458960 BXGD008909 Peripheral neuropathic pain
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0522055 BXGD009189 Electrocardiogram abnormal Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0541764 BXGD009259 Delayed bone age
C0546817 BXGD009342 Fluid overload Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0562350 BXGD009476 Hip circumference
C0574785 BXGD009506 Lower Urinary Tract Symptoms Pathological Conditions, Signs and Symptoms
C0595948 BXGD009630 Atypical absence seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600142 BXGD009696 Hot flushes Pathological Conditions, Signs and Symptoms
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686347 BXGD009832 Tardive Dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0741682 BXGD010039 Premenopausal breast cancer
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751371 BXGD010415 Neuralgia, Ilioinguinal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751372 BXGD010416 Nerve Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751373 BXGD010417 Paroxysmal Nerve Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751529 BXGD010492 Stuttering, Developmental Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0848676 BXGD010883 Subfertility, Male Male Urogenital Diseases
C0852654 BXGD010947 21-hydroxylase deficiency
C0857898 BXGD011165 Abnormal circulating aldosterone
C0871470 BXGD011316 Systolic Pressure
C0877008 BXGD011325 Enzyme inhibition disorder
C0917730 BXGD011406 Female sterility Female Urogenital Diseases and Pregnancy Complications
C0917731 BXGD011407 Male sterility Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C0947622 BXGD011493 Cholecystolithiasis Digestive System Diseases
C0948896 BXGD011563 Primary hypogonadism Endocrine System Diseases
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C0949691 BXGD011585 Spondylarthropathies Musculoskeletal Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1275126 BXGD012062 TNF receptor-associated periodic fever syndrome (TRAPS) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1291314 BXGD012209 Deficiency of monooxygenase
C1291557 BXGD012217 Deficiency of lyase
C1298820 BXGD012252 Aneurysm of aortic root Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306620 BXGD012371 Systolic blood pressure measurement
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1333990 BXGD012670 Hereditary Nonpolyposis Colorectal Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384514 BXGD012940 Conn Syndrome Endocrine System Diseases
C1384583 BXGD012942 Congenital absence of germinal epithelium of testes Male Urogenital Diseases
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621895 BXGD013466 Adrenal hyperplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Endocrine System Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1654637 BXGD013484 androgen independent prostate cancer
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1739135 BXGD013733 Progression of prostate cancer
C1832232 BXGD013812 Peroxisome Biogenesis Disorder, Complementation Group C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1837315 BXGD014218 COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
C1845206 BXGD014727 Decreased circulating renin level
C1848178 BXGD014909 Female external genitalia in individual with 46,XY karyotype
C1852222 BXGD015265 Failure of Tooth Eruption, Primary Stomatognathic Diseases
C1853195 BXGD015313 Prostate Cancer, Hereditary, 7 Neoplasms; Male Urogenital Diseases
C1853926 BXGD015365 NONAKA MYOPATHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858573 BXGD015809 Sparse pubic hair
C1858574 BXGD015810 Sparse axillary hair
C1859014 BXGD015843 Primary gonadal insufficiency
C1862863 BXGD016138 Sparse body hair
C1867743 BXGD016470 Premature coronary artery atherosclerosis Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2675481 BXGD017292 COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
C2677123 BXGD017364 COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2931456 BXGD018024 Prostate cancer, familial Neoplasms; Male Urogenital Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2936858 BXGD018147 Congenital adrenal hyperplasia due to 21 hydroxylase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C2937421 BXGD018162 Prostatic Hyperplasia Male Urogenital Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3275124 BXGD018660 Biliary System Disorder
C3277849 BXGD018723 17,20-Lyase Deficiency, Isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C3469522 BXGD018911 BREAST CANCER, SUSCEPTIBILITY TO
C3489396 BXGD018929 Hypogonadism, Isolated Hypogonadotropic Endocrine System Diseases
C3495917 BXGD019012 Advanced breast cancer
C3539781 BXGD019086 Progressive cGVHD
C3554460 BXGD019215 COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
C3714760 BXGD019432 Drug-induced tardive dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C4021124 BXGD020560 Adrenocorticotropic hormone excess Nervous System Diseases; Endocrine System Diseases
C4021550 BXGD020666 Elevated circulating follicle stimulating hormone level
C4021551 BXGD020667 Absence of secondary sex characteristics
C4021740 BXGD020748 Increased circulating ACTH level
C4021823 BXGD020808 Ambiguous genitalia, male Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C4022996 BXGD021057 Abnormal sex determination
C4023101 BXGD021106 Elevated circulating luteinizing hormone level
C4024641 BXGD021355 Enlarged polycystic ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4024878 BXGD021453 Generalized hyperpigmentation Skin and Connective Tissue Diseases
C4073137 BXGD022045 Decreased serum testosterone level
C4083212 BXGD022105 Alopecia, Male Pattern Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C4284013 BXGD022428 Primary cholangiocarcinoma of intrahepatic biliary tract Neoplasms
C4329212 BXGD022783 17-Alpha-Hydroxylase/17,20 Lyase Deficiency
C4331229 BXGD022810 Recurrent Glioma Neoplasms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4551492 BXGD023317 Micropenis
C4552100 BXGD023488 Lynch Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721208 BXGD023733 Metastatic castration-resistant prostate cancer
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001325 Progesterone 314.46
BXGC0003611 Latex 416.57
BXGC0008676 Haem 616.49
BXGC0018403 Hydroxyprogesterone 330.22
BXGC0029355 Pregnenolone 316.24
BXGC0040150 Cannabidiol 314.22
BXGC0046139 Aminoglutethimide 232.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein