Showing entry for Hereditary Malignant Neoplasm


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012636
Disease NameHereditary Malignant Neoplasm
Disease CUI IdC1333600
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01275 BXGT005747 Glucagon 2641 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12830 BXGT007852 Cadherin-1 999 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15941 BXGT008176 Mucin-1 4582 reviewed
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P49959 BXGT010766 Double-strand break repair protein MRE11 4361 reviewed
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16584 BXGT013642 Mitogen-activated protein kinase kinase kinase 11 4296 reviewed Kinase
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8WWM9 BXGT019001 Cytoglobin 114757 reviewed
Q92547 BXGT019355 DNA topoisomerase 2-binding protein 1 11073 reviewed
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q99728 BXGT019956 BRCA1-associated RING domain protein 1 580 reviewed
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
P35240 BXGT022927 Merlin 4771 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q92878 BXGT023071 DNA repair protein RAD50 10111 reviewed
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease