Showing entry for Pyridoxal phosphate phosphatase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019665
Protein NamePyridoxal phosphate phosphatase
Uniport IdQ96GD0
GenePDXP
Gene Id57026
DomainHydrolase_6; Hydrolase_like
Pfam PF13344  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00750 Vitamin B6 metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031247 actin rod assembly
Biological Process GO:0071318 cellular response to ATP
Biological Process GO:0016311 dephosphorylation
Biological Process GO:0006114 glycerol biosynthetic process
Biological Process GO:0006650 glycerophospholipid metabolic process
Biological Process GO:0030836 positive regulation of actin filament depolymerization
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0032361 pyridoxal phosphate catabolic process
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0007088 regulation of mitotic nuclear division
molecular function GO:0043136 glycerol-3-phosphatase activity
molecular function GO:0031072 heat shock protein binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0016791 phosphatase activity
molecular function GO:0004721 phosphoprotein phosphatase activity
molecular function GO:0004647 phosphoserine phosphatase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0033883 pyridoxal phosphatase activity
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0031258 lamellipodium membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005967 BXGD000357 Bone neoplasms Neoplasms; Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007860 BXGD000495 Uterine Cervicitis Female Urogenital Diseases and Pregnancy Complications
C0007867 BXGD000497 Cervix Diseases Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009663 BXGD000618 Condylomata Acuminata Infections; Skin and Connective Tissue Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011303 BXGD000712 Demyelinating Diseases Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014126 BXGD000897 Endocervical polyp Pathological Conditions, Signs and Symptoms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017097 BXGD001092 Gardner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020630 BXGD001454 Hypophosphatasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023520 BXGD001678 Leukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0024530 BXGD001783 Malaria Infections
C0025202 BXGD001832 melanoma Neoplasms
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030354 BXGD002214 Papilloma Neoplasms
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037772 BXGD002703 Spastic Paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037773 BXGD002704 Spastic Paraplegia, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0039585 BXGD002821 Androgen-Insensitivity Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0205622 BXGD004092 Microinvasive tumor
C0205711 BXGD004113 Pelizaeus-Merzbacher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220810 BXGD004346 Congenital defects
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0268074 BXGD005810 Indian childhood cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Respiratory Tract Diseases
C0268164 BXGD005844 Primary hyperoxaluria, type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270733 BXGD006095 Striatonigral Degeneration Nervous System Diseases
C0270922 BXGD006134 Peripheral demyelinating neuropathy Immune System Diseases; Nervous System Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278803 BXGD006593 Adenocarcinoma of small intestine Digestive System Diseases; Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0302180 BXGD006833 Condyloma
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333693 BXGD006964 Triploidy syndrome Pathological Conditions, Signs and Symptoms
C0333873 BXGD006971 Squamous intraepithelial lesion Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333875 BXGD006972 High-Grade Squamous Intraepithelial Lesions Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334276 BXGD007016 Adenocarcinoma in Situ Pathological Conditions, Signs and Symptoms; Neoplasms
C0343641 BXGD007636 Human papilloma virus infection Infections
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346203 BXGD007800 Cervical Adenocarcinoma In Situ Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346208 BXGD007801 Vaginal intraepithelial neoplasia Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346210 BXGD007802 Vulval intraepithelial neoplasia Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0349458 BXGD007906 Cervical intraepithelial neoplasia grade 1 Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0349459 BXGD007907 Cervical intraepithelial neoplasia grade 2 Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0349555 BXGD007925 Vaginal intraepithelial neoplasia grade 2
C0375071 BXGD007972 Malignant neoplasm of vulva Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0392885 BXGD008071 High density lipoprotein measurement
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0443306 BXGD008817 Spastic Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0520739 BXGD009106 Hereditary pyropoikilocytosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0549523 BXGD009386 Oropharynx (excludes nasopharynx)
C0553694 BXGD009409 Oropharyngeal disorders Digestive System Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0677055 BXGD009715 CARCINOMA OF VULVA Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0677898 BXGD009735 invasive cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751604 BXGD010522 Hereditary X-Linked Recessive Spastic Paraplegia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751967 BXGD010657 Multiple Sclerosis, Relapsing-Remitting Immune System Diseases; Nervous System Diseases
C0795953 BXGD010770 MASA SYNDROME (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0815107 BXGD010861 psychological distress
C0851140 BXGD010916 Carcinoma in situ of uterine cervix Neoplasms
C0878500 BXGD011365 Intraepithelial Neoplasia Neoplasms
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948075 BXGD011502 Anal infection Digestive System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1302773 BXGD012312 Low Grade Squamous Intraepithelial Neoplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1320453 BXGD012422 Cervical Squamous Cell Carcinoma In Situ Neoplasms
C1332922 BXGD012556 Cervical Squamous Intraepithelial Neoplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333148 BXGD012602 Conjunctival intraepithelial neoplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases
C1333600 BXGD012636 Hereditary Malignant Neoplasm Neoplasms
C1334011 BXGD012676 High Grade Cervical Intraepithelial Neoplasia Neoplasms
C1334177 BXGD012684 Infiltrating Cervical Carcinoma
C1334274 BXGD012695 Invasive Carcinoma Neoplasms
C1336109 BXGD012834 Stage IA1 Cervical Cancer
C1445957 BXGD013081 Serum total cholesterol measurement
C1512127 BXGD013185 HER2 gene amplification
C1512433 BXGD013191 Cervical high grade squamous intraepithelial lesion Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1518005 BXGD013224 Low Grade Cervical Squamous Intraepithelial Neoplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1519689 BXGD013245 Tumor Promotion Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1839264 BXGD014364 SPASTIC PARAPLEGIA 2, X-LINKED (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1849156 BXGD015017 Spastic Ataxia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1864723 BXGD016246 Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2986622 BXGD018231 Cervical Intraepithelial Neoplasia Grade 2/3
C2987516 BXGD018256 Cervix Intraepithelial Neoplasia Grade 3 AJCC v7 Neoplasms
C3495426 BXGD018983 Homocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3642346 BXGD019245 Luminal B Breast Carcinoma
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4274084 BXGD022344 Pelizaeus Merzbacher like disease
C4551583 BXGD023361 Cerebral cortical atrophy
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0043088 Pyridoxal Phosphate 247.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein