adisease

Showing entry for Hereditary Non-Polyposis Colon Cancer Type 2

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD012671
Disease Name	Hereditary Non-Polyposis Colon Cancer Type 2
Disease CUI Id	C1333991
MeSH Codes	C16 C04
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	11200	reviewed	Kinase
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P12830	BXGT007852	Cadherin-1	999	reviewed
P35221	BXGT009798	Catenin alpha-1	1495	reviewed	Cellular structure
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
Q12913	BXGT013279	Receptor-type tyrosine-protein phosphatase eta	5795	reviewed	Enzyme
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13426	BXGT013353	DNA repair protein XRCC4	7518	reviewed
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q99728	BXGT019956	BRCA1-associated RING domain protein 1	580	reviewed
Q9UQ84	BXGT021807	Exonuclease 1	9156	reviewed	Enzyme
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}