Showing entry for Bulbo-Spinal Atrophy, X-Linked


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD014363
Disease NameBulbo-Spinal Atrophy, X-Linked
Disease CUI IdC1839259
MeSH Codes C16   C10  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O60271 BXGT004866 C-Jun-amino-terminal kinase-interacting protein 4 9043 reviewed Enzyme modulator
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P31689 BXGT009569 DnaJ homolog subfamily A member 1 3301 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42262 BXGT010294 Glutamate receptor 2 2891 reviewed Ion channel
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42858 BXGT010341 Huntingtin 3064 reviewed
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P62826 BXGT011463 GTP-binding nuclear protein Ran 5901 reviewed Enzyme modulator
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q12830 BXGT013268 Nucleosome-remodeling factor subunit BPTF 2186 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q14416 BXGT013468 Metabotropic glutamate receptor 2 2912 reviewed G-protein coupled receptor
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q92598 BXGT019356 Heat shock protein 105 kDa 10808 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92830 BXGT019379 Histone acetyltransferase KAT2A 2648 reviewed
Q92831 BXGT019380 Histone acetyltransferase KAT2B 8850 reviewed
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase 55872 reviewed Kinase
Q96LA8 BXGT019691 Protein arginine N-methyltransferase 6 55170 reviewed Epigenetic regulator
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9NUX5 BXGT021220 Protection of telomeres protein 1 25913 reviewed Nucleic acid binding
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha 6328 reviewed Ion channel
Q9ULV0 BXGT021763 Unconventional myosin-Vb 4645 reviewed Cellular structure
Q16181 BXGT024892 Septin-7 989 reviewed Enzyme modulator
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease