Showing entry for Intellectual disability, progressive


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD014786
Disease NameIntellectual disability, progressive
Disease CUI IdC1846149
MeSH Codes C23   C10   F03   F01  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic TypeFinding
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00189 BXGT003891 AP-4 complex subunit mu-1 9179 reviewed Extracellular structure
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P41229 BXGT010239 Lysine-specific demethylase 5C 8242 reviewed
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
Q00604 BXGT012538 Norrin 4693 reviewed
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q03393 BXGT012711 6-pyruvoyl tetrahydrobiopterin synthase 5805 reviewed
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q10469 BXGT013200 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 4247 reviewed Enzyme
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease