Showing entry for GTP cyclohydrolase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009466
Protein NameGTP cyclohydrolase 1
Uniport IdP30793
GeneGCH1
Gene Id2643
DomainGTP_cyclohydroI
Pfam PF01227  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035998 7,8-dihydroneopterin 3'-triphosphate biosynthetic process
Biological Process GO:0042416 dopamine biosynthetic process
Biological Process GO:0045776 negative regulation of blood pressure
Biological Process GO:0050884 neuromuscular process controlling posture
Biological Process GO:0006809 nitric oxide biosynthetic process
Biological Process GO:0010460 positive regulation of heart rate
Biological Process GO:0051000 positive regulation of nitric-oxide synthase activity
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0042559 pteridine-containing compound biosynthetic process
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0014916 regulation of lung blood pressure
Biological Process GO:2000121 regulation of removal of superoxide radicals
Biological Process GO:0034341 response to interferon-gamma
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0048265 response to pain
Biological Process GO:0034612 response to tumor necrosis factor
Biological Process GO:0006729 tetrahydrobiopterin biosynthetic process
Biological Process GO:0046654 tetrahydrofolate biosynthetic process
Biological Process GO:0042311 vasodilation
molecular function GO:0005509 calcium ion binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0003934 GTP cyclohydrolase I activity
molecular function GO:0030742 GTP-dependent protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0051019 mitogen-activated protein kinase binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0031369 translation initiation factor binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0044306 neuron projection terminus
cellular component GO:0031965 nuclear membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-8978934 Metabolism of cofactors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007398 BXGD000465 Catatonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013132 BXGD000799 Drooling Stomatognathic Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013386 BXGD000827 Dyskinesia, Drug-Induced Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013423 BXGD000838 Dystonia Musculorum Deformans Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0015371 BXGD000978 Extrapyramidal Disorders Nervous System Diseases
C0015393 BXGD000981 Eye Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015674 BXGD001012 Chronic Fatigue Syndrome Infections; Musculoskeletal Diseases; Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018553 BXGD001203 Hamartoma Syndrome, Multiple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0022107 BXGD001530 Irritable Mood Behavior and Behavior Mechanisms
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0026858 BXGD001944 Musculoskeletal Pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0026918 BXGD001948 Mycobacterium Infections Infections
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027849 BXGD002049 Neuroleptic Malignant Syndrome Nervous System Diseases; Chemically-Induced Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028768 BXGD002084 Obsessive-Compulsive Disorder Mental Disorders
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031485 BXGD002303 Phenylketonurias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0032768 BXGD002370 Postherpetic neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034935 BXGD002497 Babinski Reflex
C0035021 BXGD002501 Relapsing Fever Infections
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037036 BXGD002661 Sialorrhea Stomatognathic Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037772 BXGD002703 Spastic Paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0040485 BXGD002871 Torticollis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041408 BXGD002923 Turner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0085583 BXGD003194 Choreoathetosis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086439 BXGD003284 Hypokinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151564 BXGD003440 Cogwheel Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0162701 BXGD003978 Polysomnography
C0162835 BXGD003989 Hypopigmentation disorder Skin and Connective Tissue Diseases
C0202202 BXGD004082 Protein measurement
C0220810 BXGD004346 Congenital defects
C0221727 BXGD004470 Pain in esophagus (finding)
C0231519 BXGD004495 Gegenhalten Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233608 BXGD004595 Catatonic Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0234230 BXGD004635 Pain, Burning Pathological Conditions, Signs and Symptoms
C0234238 BXGD004637 Ache Pathological Conditions, Signs and Symptoms
C0234245 BXGD004641 Visceral Pain Pathological Conditions, Signs and Symptoms
C0234252 BXGD004646 Mechanical pain Pathological Conditions, Signs and Symptoms
C0234254 BXGD004648 Radiating pain Pathological Conditions, Signs and Symptoms
C0234378 BXGD004661 Static Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0239325 BXGD004977 Extensor Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0241210 BXGD005086 Speech Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0242684 BXGD005188 Hypodynamia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0264162 BXGD005369 Camptocormia Musculoskeletal Diseases; Nervous System Diseases
C0267937 BXGD005792 Acute recurrent pancreatitis Digestive System Diseases
C0268464 BXGD005954 Transient hyperphenylalaninemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268465 BXGD005955 Phenylketonuria II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268467 BXGD005956 Hyperphenylalaninemia, BH4-Deficient, B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268468 BXGD005957 Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Behavior and Behavior Mechanisms
C0269084 BXGD006052 Vulvar Vestibulitis Female Urogenital Diseases and Pregnancy Complications
C0271385 BXGD006193 Horizontal Nystagmus Eye Diseases; Nervous System Diseases
C0271561 BXGD006213 Somatotropin deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0277821 BXGD006478 Extrapyramidal Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0391976 BXGD008022 Pain Disorder Mental Disorders
C0392885 BXGD008071 High density lipoprotein measurement
C0393576 BXGD008096 Chorea Acanthocytosis Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393584 BXGD008099 Benign Hereditary Chorea Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0393588 BXGD008100 Dystonia, Paroxysmal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0393593 BXGD008103 Dystonia Disorders Nervous System Diseases
C0393610 BXGD008107 Dystonia, Diurnal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424230 BXGD008522 Motor retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0458257 BXGD008905 Pain, Splitting Pathological Conditions, Signs and Symptoms
C0458259 BXGD008906 Pain, Crushing Pathological Conditions, Signs and Symptoms
C0474368 BXGD008950 Labor Pain Pathological Conditions, Signs and Symptoms
C0497202 BXGD009055 Abnormal ocular motility
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0575157 BXGD009514 Deformity of spine
C0596240 BXGD009638 Cancer Pain Pathological Conditions, Signs and Symptoms
C0596887 BXGD009648 mathematical ability
C0600104 BXGD009690 Obsessive compulsive behavior Behavior and Behavior Mechanisms
C0686347 BXGD009832 Tardive Dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0686377 BXGD009834 CNS metastases Neoplasms; Nervous System Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0743332 BXGD010081 Focal Dystonia Nervous System Diseases
C0750403 BXGD010235 Proximal weakness
C0751088 BXGD010316 Dyskinesia, Medication-Induced Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C0751093 BXGD010317 Dystonia, Limb Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751407 BXGD010429 Pain, Migratory Pathological Conditions, Signs and Symptoms
C0751408 BXGD010430 Suffering, Physical Pathological Conditions, Signs and Symptoms
C0751435 BXGD010440 Hyperphenylalaninaemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0751436 BXGD010441 Hyperphenylalaninemia, Non-Phenylketonuric Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0751701 BXGD010558 Hypokinesia, Antiorthostatic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751837 BXGD010604 Gait Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0752105 BXGD010664 Parkinsonism, Juvenile Nervous System Diseases
C0752202 BXGD010691 Childhood Onset Dystonias Nervous System Diseases
C0752203 BXGD010692 Dystonia, Primary Nervous System Diseases
C0752205 BXGD010693 Dystonia, Secondary Nervous System Diseases
C0752207 BXGD010695 Familial Dystonia Nervous System Diseases
C0796074 BXGD010793 MOHR-TRANEBJAERG SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Mental Disorders; Otorhinolaryngologic Diseases; Behavior and Behavior Mechanisms
C0849640 BXGD010889 skin damage
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0856169 BXGD011096 Endothelial dysfunction
C0860603 BXGD011236 Anxiety symptoms
C0878676 BXGD011385 6-pyruvoyl-tetrahydropterin synthase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0949445 BXGD011575 Cervical Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1263855 BXGD011899 Lumbar radiculopathy Nervous System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1320474 BXGD012425 Nuchal Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1414216 BXGD013054 Dystonia 6, torsion (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1445953 BXGD013080 Poor eye contact Mental Disorders
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1504405 BXGD013142 Pyramidal Tract Dysfunction Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1834570 BXGD013981 Myoclonic dystonia Nervous System Diseases
C1836150 BXGD014082 Gait imbalance
C1836696 BXGD014151 Lower limb hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1837352 BXGD014223 Childhood onset
C1838391 BXGD014313 Limb hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1839630 BXGD014391 Severe muscular hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1842534 BXGD014522 DYSTONIA 18 (disorder) Nervous System Diseases
C1846149 BXGD014786 Intellectual disability, progressive Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1846868 BXGD014846 Parkinsonism with favorable response to dopaminergic medication Nervous System Diseases
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1848954 BXGD014989 Generalized dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1849134 BXGD015010 Impaired vibration sensation in the lower limbs
C1851920 BXGD015246 Dopa-Responsive Dystonia Nervous System Diseases
C1851945 BXGD015249 DYSTONIA 1, TORSION, AUTOSOMAL DOMINANT Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1854838 BXGD015438 Progressive neurologic deterioration Mental Disorders
C1855483 BXGD015501 Progressive spastic paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861403 BXGD016045 Variable expressivity
C1868596 BXGD016513 Atypical Parkinson Disease Nervous System Diseases
C1868675 BXGD016520 PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE Nervous System Diseases
C1868681 BXGD016524 DYSTONIA 12 Nervous System Diseases
C1869117 BXGD016550 Paroxysmal nonkinesigenic dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2242577 BXGD016980 Oromandibular dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2609253 BXGD017172 Macrovascular disease
C2673535 BXGD017210 DYSTONIA, DOPA-RESPONSIVE, WITH OR WITHOUT HYPERPHENYLALANINEMIA, AUTOSOMAL RECESSIVE (disorder) Nervous System Diseases
C2673700 BXGD017223 Brisk reflexes Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2700617 BXGD017474 Irritation - emotion Behavior and Behavior Mechanisms
C2717866 BXGD017514 Vestibulodynia Female Urogenital Diseases and Pregnancy Complications
C2931845 BXGD018076 Neurodegeneration with brain iron accumulation (NBIA) Nutritional and Metabolic Diseases; Nervous System Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3178789 BXGD018537 Widespread Chronic Pain Pathological Conditions, Signs and Symptoms
C3279322 BXGD018752 Progressive flexion contractures
C3714760 BXGD019432 Drug-induced tardive dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C3714772 BXGD019433 Recurrent fevers
C3714796 BXGD019434 Isolated somatotropin deficiency
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887506 BXGD019886 Hyperkinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3888090 BXGD019948 Early onset torsion dystonia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4022403 BXGD020897 Abnormality of the substantia nigra
C4025696 BXGD021737 Paresis of extensor muscles of the big toe
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4275179 BXGD022368 Young onset Parkinson disease Nervous System Diseases
C4280803 BXGD022407 Decreased CSF homovanillic acid
C4316810 BXGD022702 Writer's Cramp Nervous System Diseases
C4524082 BXGD023089 Segawa syndrome
C4551506 BXGD023326 Paroxysmal Nonkinesigenic Dyskinesia 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4552810 BXGD023525 Irritability, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002912 Guanine 151.13
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein