Showing entry for Progressive spastic paraplegia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD015501
Disease NameProgressive spastic paraplegia
Disease CUI IdC1855483
MeSH Codes C23   C10  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic TypeFinding
Human Phenotype Ontology Id HP:0000707   HP:0003011  
Human Phenotype Ontology TermAbnormality of the nervous system; Abnormality of the musculature
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00189 BXGT003891 AP-4 complex subunit mu-1 9179 reviewed Extracellular structure
O00217 BXGT003898 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 4728 reviewed Enzyme
O00483 BXGT003930 Cytochrome c oxidase subunit NDUFA4 4697 reviewed Enzyme
O43181 BXGT004576 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4724 reviewed
O43678 BXGT004613 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 4695 reviewed Enzyme
O75251 BXGT005107 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 374291 reviewed
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O95299 BXGT005372 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 4705 reviewed Enzyme
O95363 BXGT005375 Phenylalanine--tRNA ligase, mitochondrial 10667 reviewed Enzyme
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P08559 BXGT006788 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 5160 reviewed
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P30084 BXGT009398 Enoyl-CoA hydratase, mitochondrial 1892 reviewed Enzyme
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P41229 BXGT010239 Lysine-specific demethylase 5C 8242 reviewed
P48643 BXGT010650 T-complex protein 1 subunit epsilon 22948 reviewed Chaperone
P49821 BXGT010748 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 4723 reviewed
P56192 BXGT011149 Methionine--tRNA ligase, cytoplasmic 4141 reviewed
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q16795 BXGT013671 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 4704 reviewed Enzyme
Q8N183 BXGT018497 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 91942 reviewed
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 51079 reviewed Enzyme
Q9UI09 BXGT021710 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 55967 reviewed
Q9Y234 BXGT022211 Lipoyltransferase 1, mitochondrial 51601 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease