Showing entry for SPHEROCYTOSIS, TYPE 1 (disorder)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD017240
Disease NameSPHEROCYTOSIS, TYPE 1 (disorder)
Disease CUI IdC2674218
MeSH Codes C16   C15  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O43612 BXGT004605 Orexin 3060 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02549 BXGT005890 Spectrin alpha chain, erythrocytic 1 6708 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16157 BXGT008203 Ankyrin-1 286 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P39086 BXGT010093 Glutamate receptor ionotropic, kainate 1 2897 reviewed Ion channel
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NRW4 BXGT021196 Dual specificity protein phosphatase 22 56940 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease