Showing entry for Glutamate receptor ionotropic, NMDA 2A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013275
Protein NameGlutamate receptor ionotropic, NMDA 2A
Uniport IdQ12879
GeneGRIN2A
Gene Id2903
DomainANF_receptor; Lig_chan; Lig_chan-Glu_bd; NMDAR2_C
Pfam PF01094   PF00060   PF10613   PF10565  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.10 Environmental adaptation hsa04713 Circadian entrainment
5. Organismal Systems 5.6 Nervous system hsa04720 Long-term potentiation
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
5. Organismal Systems 5.6 Nervous system hsa04728 Dopaminergic synapse
6. Human Diseases 6.4 Neurodegenerative diseases hsa05010 Alzheimer disease
6. Human Diseases 6.4 Neurodegenerative diseases hsa05014 Amyotrophic lateral sclerosis (ALS)
6. Human Diseases 6.5 Substance dependence hsa05030 Cocaine addiction
6. Human Diseases 6.5 Substance dependence hsa05031 Amphetamine addiction
6. Human Diseases 6.5 Substance dependence hsa05033 Nicotine addiction
6. Human Diseases 6.5 Substance dependence hsa05034 Alcoholism
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097202 activation of cysteine-type endopeptidase activity
Biological Process GO:0007420 brain development
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0033058 directional locomotion
Biological Process GO:0042417 dopamine metabolic process
Biological Process GO:0098976 excitatory chemical synaptic transmission
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0007215 glutamate receptor signaling pathway
Biological Process GO:0007611 learning or memory
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0007613 memory
Biological Process GO:0042177 negative regulation of protein catabolic process
Biological Process GO:0022008 neurogenesis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:1903539 protein localization to postsynaptic membrane
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0009611 response to wounding
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042428 serotonin metabolic process
Biological Process GO:0030431 sleep
Biological Process GO:0001964 startle response
Biological Process GO:0008542 visual learning
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0022849 glutamate-gated calcium ion channel activity
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0038023 signaling receptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0009986 cell surface
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0043197 dendritic spine
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
R-HSA-212436 Generic Transcription Pathway
R-HSA-438064 Post NMDA receptor activation events
R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation
R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-6794361 Neurexins and neuroligins
R-HSA-6794362 Protein-protein interactions at synapses
R-HSA-6794362 Protein-protein interactions at synapses
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8849932 Synaptic adhesion-like molecules
R-HSA-8986944 Transcriptional Regulation by MECP2
R-HSA-9022699 MECP2 regulates neuronal receptors and channels
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission
R-HSA-9620244 Long-term potentiation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001816 BXGD000079 Agnosia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003537 BXGD000208 Aphasia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0003635 BXGD000214 Apraxias Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005587 BXGD000316 Depression, Bipolar Mental Disorders
C0006009 BXGD000359 Borderline intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0009090 BXGD000586 Cluttering Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013132 BXGD000799 Drooling Stomatognathic Diseases
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014547 BXGD000927 Epilepsies, Partial Nervous System Diseases
C0014548 BXGD000928 Epilepsy, Generalized Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023012 BXGD001599 Language Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023014 BXGD001600 Language Development Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023015 BXGD001601 Language Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023066 BXGD001605 Laryngospasm Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024713 BXGD001799 Manic Disorder Mental Disorders
C0025202 BXGD001832 melanoma Neoplasms
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026552 BXGD001906 Morphine Dependence Chemically-Induced Disorders; Mental Disorders
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027438 BXGD001989 Nasopharyngeal Diseases Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0027441 BXGD001991 Nasopharyngitis Infections; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0029227 BXGD002123 Delirium, Dementia, Amnestic, Cognitive Disorders Mental Disorders
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032051 BXGD002326 Placental Insufficiency Female Urogenital Diseases and Pregnancy Complications
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037315 BXGD002687 Sleep Apnea Syndromes Respiratory Tract Diseases; Nervous System Diseases
C0037769 BXGD002701 West Syndrome Nervous System Diseases
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038587 BXGD002773 Substance Withdrawal Syndrome Chemically-Induced Disorders; Mental Disorders
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0085648 BXGD003221 Synovial Cyst Neoplasms
C0086189 BXGD003268 Drug Withdrawal Symptoms Chemically-Induced Disorders; Mental Disorders
C0086237 BXGD003273 Epilepsy, Cryptogenic Nervous System Diseases
C0087169 BXGD003321 Withdrawal Symptoms Chemically-Induced Disorders; Mental Disorders
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151888 BXGD003497 Hyporeflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0206715 BXGD004261 Neoplasms, Neuroepithelial Neoplasms
C0206716 BXGD004262 Ganglioglioma Neoplasms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233726 BXGD004606 Aprosodia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0234516 BXGD004681 Speech dysfunction
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0236018 BXGD004804 Aura Nervous System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0241210 BXGD005086 Speech Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262630 BXGD005262 Reduced concentration span Behavior and Behavior Mechanisms
C0264611 BXGD005403 Apraxia of Phonation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0265101 BXGD005454 Carotid artery occlusion Nervous System Diseases; Cardiovascular Diseases
C0270850 BXGD006117 Idiopathic generalized epilepsy Nervous System Diseases
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0282512 BXGD006807 Landau-Kleffner Syndrome Nervous System Diseases
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338831 BXGD007216 Manic Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0348165 BXGD007868 Central Nervous System Viral Diseases Infections; Nervous System Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349588 BXGD007933 Short stature
C0376532 BXGD008000 Epilepsy, Rolandic Nervous System Diseases
C0392699 BXGD008064 Dysesthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0432283 BXGD008764 Osteoglophonic dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0438696 BXGD008805 Suicidal Behavior and Behavior Mechanisms
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0454655 BXGD008852 Semantic-Pragmatic Disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0494475 BXGD009030 Tonic - clonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524662 BXGD009238 Opiate Addiction Chemically-Induced Disorders; Mental Disorders
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0566620 BXGD009490 Nasal voice
C0595948 BXGD009630 Atypical absence seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0598275 BXGD009664 Diffuse cerebral atrophy Nervous System Diseases; Mental Disorders
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0600272 BXGD009702 Morphine Abuse Chemically-Induced Disorders; Mental Disorders
C0678356 BXGD009755 alcohol effect
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751111 BXGD010319 Awakening Epilepsy Nervous System Diseases
C0751257 BXGD010367 Auditory Processing Disorder, Central Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751512 BXGD010485 Dysglossia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751513 BXGD010486 Rhinolalia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751514 BXGD010487 Verbal Fluency Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0752308 BXGD010715 Hypoxia-Ischemia, Brain Nervous System Diseases; Cardiovascular Diseases
C0752335 BXGD010720 Neuropsychiatric Systemic Lupus Erythematosus Infections; Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0877017 BXGD011329 Generalized tonic-clonic seizures with focal onset Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0940937 BXGD011490 precancerous lesions
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0973461 BXGD011595 Dysphasia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1112263 BXGD011658 Atypical benign partial epilepsy
C1258666 BXGD011825 Myxoid cyst Neoplasms; Skin and Connective Tissue Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1504404 BXGD013141 Hippocampal sclerosis
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1527366 BXGD013280 Salaam Seizures Nervous System Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1836038 BXGD014073 Poor head control Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1836508 BXGD014124 Generalized tonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1838027 BXGD014290 Incomprehensible speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1847514 BXGD014868 Postnatal microcephaly
C1854114 BXGD015383 Short nose
C1857704 BXGD015741 Abnormal myelination
C1861403 BXGD016045 Variable expressivity
C1865313 BXGD016311 Speech articulation difficulties
C2363129 BXGD017095 Benign Rolandic Epilepsy Nervous System Diseases
C2674218 BXGD017240 SPHEROCYTOSIS, TYPE 1 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C2677180 BXGD017366 Congenital microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2678194 BXGD017400 Mental Retardation, X-Linked, Syndromic, Christianson Type Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C2919142 BXGD017867 Short Stature, CTCAE
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3495145 BXGD018980 Dyslalia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3553450 BXGD019175 Profound global developmental delay
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806402 BXGD019507 EPILEPSY, FOCAL, WITH SPEECH DISORDER AND WITH OR WITHOUT MENTAL RETARDATION
C3806403 BXGD019508 Continuous spike and waves during slow sleep
C3806604 BXGD019520 Infantile axial hypotonia
C3887898 BXGD019926 Infantile Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4022848 BXGD021011 EEG with centrotemporal focal spike waves
C4022855 BXGD021013 Abnormal involuntary eye movements
C4023014 BXGD021067 Stereotypical hand wringing Mental Disorders
C4023476 BXGD021197 EEG with generalized epileptiform discharges
C4023478 BXGD021199 EEG with focal sharp waves
C4023687 BXGD021243 EEG with multifocal slow activity
C4023915 BXGD021274 Abnormally low-pitched voice
C4024906 BXGD021465 Hemifacial seizures Nervous System Diseases
C4025790 BXGD021791 Specific learning disability
C4025792 BXGD021792 EEG with irregular generalized spike and wave complexes
C4049830 BXGD021953 Focal seizures, afebril Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4285693 BXGD022446 HIV-associated neurocognitive disorder Infections; Immune System Diseases
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4505072 BXGD022953 Epileptic Syndromes Nervous System Diseases
C4531122 BXGD023190 Abnormal speech prosody
C4749281 BXGD024053 Early-onset epileptic encephalopathy and intellectual disability due to GRIN2A mutation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000436 Glycerol 92.09
BXGC0002390 Spermine 202.34
BXGC0002586 Calcium 40.08
BXGC0003196 Aripiprazole 448.39
BXGC0006162 L-Glutamic acid 147.13
BXGC0025485 Transtorine 189.04
BXGC0028885 Secobarbital 238.13
BXGC0033112 Acetylcysteine 163.03
BXGC0043578 5-Hydroxy-2-(2-Phenylethyl)Chromen-4-One 266.09
BXGC0049447 acetate 59.01
BXGC0050816 Galantamine 287.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein