adisease

Showing entry for Neurodegeneration with brain iron accumulation (NBIA)

General Disease Information
BXGD Id	BXGD018076
Disease Name	Neurodegeneration with brain iron accumulation (NBIA)
Disease CUI Id	C2931845
MeSH Codes	C18 C10
Disease Class Name	Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P43155	BXGT010363	Carnitine O-acetyltransferase	1384	reviewed	Enzyme
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P51688	BXGT010883	N-sulphoglucosamine sulphohydrolase	6448	reviewed	Enzyme
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q8TE04	BXGT018818	Pantothenate kinase 1	53354	reviewed	Kinase
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9Y3I1	BXGT022260	F-box only protein 7	25793	reviewed
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}