Showing entry for POLYCYSTIC KIDNEY DISEASE 1


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018287
Disease NamePOLYCYSTIC KIDNEY DISEASE 1
Disease CUI IdC3149841
MeSH Codes C16   C13   C12  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00330 BXGT003910 Pyruvate dehydrogenase protein X component, mitochondrial 8050 reviewed Enzyme
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
Q02880 BXGT012677 DNA topoisomerase 2-beta 7155 reviewed
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q15139 BXGT013546 Serine/threonine-protein kinase D1 5587 reviewed Kinase
Q8WUI4 BXGT018992 Histone deacetylase 7 51564 reviewed Epigenetic regulator
Q92547 BXGT019355 DNA topoisomerase 2-binding protein 1 11073 reviewed
Q9NRG4 BXGT021187 N-lysine methyltransferase SMYD2 56950 reviewed Epigenetic regulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease