Showing entry for Copper transport protein ATOX1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003902
Protein NameCopper transport protein ATOX1
Uniport IdO00244
GeneATOX1
Gene Id475
DomainHMA
Pfam PF00403  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04978 Mineral absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006878 cellular copper ion homeostasis
Biological Process GO:0060003 copper ion export
Biological Process GO:0006825 copper ion transport
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0006979 response to oxidative stress
molecular function GO:0051117 ATPase binding
molecular function GO:0016531 copper chaperone activity
molecular function GO:0032767 copper-dependent protein binding
molecular function GO:0005507 copper ion binding
molecular function GO:0016530 metallochaperone activity
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-2262752 Cellular responses to stress
R-HSA-3299685 Detoxification of Reactive Oxygen Species
R-HSA-6803157 Antimicrobial peptides
R-HSA-6803544 Ion influx/efflux at host-pathogen interface
R-HSA-8953897 Cellular responses to external stimuli
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0019189 BXGD001298 Hepatitis, Chronic Digestive System Diseases
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022716 BXGD001579 Menkes Kinky Hair Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0149519 BXGD003326 Chronic Persistent Hepatitis Digestive System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0268353 BXGD005909 Cutis laxa, x-linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0302332 BXGD006841 Poisoning syndrome
C0342687 BXGD007527 dopamine beta hydroxylase deficiency Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0524611 BXGD009235 Cryptogenic Chronic Hepatitis Digestive System Diseases
C0581384 BXGD009568 Chronic anemia Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0740302 BXGD009975 5q-syndrome Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0752120 BXGD010668 Spinocerebellar Ataxia Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1292779 BXGD012238 Myelodysplastic Syndrome with Isolated del(5q) Hemic and Lymphatic Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1802398 BXGD013758 Chromosome 5, trisomy 5q Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2945695 BXGD018187 Limb ischemia
C4087347 BXGD022144 Autosomal dominant cerebellar ataxia
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002675 Sugars 342.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein