adisease

Showing entry for Vascular Diseases

General Disease Information
BXGD Id	BXGD002978
Disease Name	Vascular Diseases
Disease CUI Id	C0042373
MeSH Codes	C14
Disease Class Name	Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	6446	reviewed	Kinase
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00244	BXGT003902	Copper transport protein ATOX1	475	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O15554	BXGT004182	Intermediate conductance calcium-activated potassium channel protein 4	3783	reviewed	Ion channel
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43915	BXGT004636	Vascular endothelial growth factor D	2277	reviewed	Signaling
O60259	BXGT004863	Kallikrein-8	11202	reviewed	Enzyme
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O60895	BXGT004907	Receptor activity-modifying protein 2	10266	reviewed	Receptor
O60911	BXGT004909	Cathepsin L2	1515	reviewed	Enzyme
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75223	BXGT005106	Gamma-glutamylcyclotransferase	79017	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95445	BXGT005381	Apolipoprotein M	55937	reviewed
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02656	BXGT005913	Apolipoprotein C-III	345	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02675	BXGT005916	Fibrinogen beta chain	2244	reviewed	Signaling
P02679	BXGT005918	Fibrinogen gamma chain	2266	reviewed	Signaling
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02749	BXGT005941	Beta-2-glycoprotein 1	350	reviewed
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02818	BXGT005969	Osteocalcin	632	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03950	BXGT006116	Angiogenin	283	reviewed
P03952	BXGT006118	Plasma kallikrein	3818	reviewed	Enzyme
P04004	BXGT006125	Vitronectin	7448	reviewed
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	3156	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07355	BXGT006609	Annexin A2	302	reviewed
P07384	BXGT006619	Calpain-1 catalytic subunit	823	reviewed	Enzyme
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08100	BXGT006725	Rhodopsin	6010	reviewed	G-protein coupled receptor
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08670	BXGT006810	Vimentin	7431	reviewed
P08709	BXGT006818	Coagulation factor VII	2155	reviewed	Enzyme
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P09958	BXGT006950	Furin	5045	reviewed	Enzyme
P0C0S5	BXGT007390	Histone H2A.Z	3015	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11597	BXGT007727	Cholesteryl ester transfer protein	1071	reviewed
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13688	BXGT007943	Carcinoembryonic antigen-related cell adhesion molecule 1	634	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14151	BXGT007990	L-selectin	6402	reviewed
P14207	BXGT007993	Folate receptor beta	2350	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16109	BXGT008194	P-selectin	6403	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16581	BXGT008245	E-selectin	6401	reviewed
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P17066	BXGT008279	Heat shock 70 kDa protein 6	3310	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17655	BXGT008325	Calpain-2 catalytic subunit	824	reviewed	Enzyme
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21333	BXGT008638	Filamin-A	2316	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21796	BXGT008690	Voltage-dependent anion-selective channel protein 1	7416	reviewed
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23467	BXGT008869	Receptor-type tyrosine-protein phosphatase beta	5787	reviewed
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P24855	BXGT008998	Deoxyribonuclease-1	1773	reviewed
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25774	BXGT009066	Cathepsin S	1520	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P28676	BXGT009284	Grancalcin	25801	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30530	BXGT009431	Tyrosine-protein kinase receptor UFO	558	reviewed	Kinase
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P32455	BXGT009640	Guanylate-binding protein 1	2633	reviewed	Enzyme modulator
P32929	BXGT009682	Cystathionine gamma-lyase	1491	reviewed	Enzyme
P33121	BXGT009692	Long-chain-fatty-acid--CoA ligase 1	2180	reviewed	Enzyme
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42702	BXGT010335	Leukemia inhibitory factor receptor	3977	reviewed	Signaling
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46736	BXGT010538	Lys-63-specific deubiquitinase BRCC36	79184	reviewed	Enzyme
P46939	BXGT010555	Utrophin	7402	reviewed
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P49765	BXGT010738	Vascular endothelial growth factor B	7423	reviewed	Signaling
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
P51677	BXGT010876	C-C chemokine receptor type 3	1232	reviewed	G-protein coupled receptor
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61586	BXGT011375	Transforming protein RhoA	387	reviewed	Enzyme modulator
P62330	BXGT011423	ADP-ribosylation factor 6	382	reviewed
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78325	BXGT011832	Disintegrin and metalloproteinase domain-containing protein 8	101	reviewed	Enzyme
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
P82279	BXGT011972	Protein crumbs homolog 1	23418	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q00604	BXGT012538	Norrin	4693	reviewed
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q08050	BXGT012958	Forkhead box protein M1	2305	reviewed
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q12965	BXGT013285	Unconventional myosin-Ie	4643	reviewed	Cellular structure
Q13093	BXGT013310	Platelet-activating factor acetylhydrolase	7941	reviewed	Enzyme
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13133	BXGT013315	Oxysterols receptor LXR-alpha	10062	reviewed	Nuclear receptor
Q13163	BXGT013321	Dual specificity mitogen-activated protein kinase kinase 5	5607	reviewed	Kinase
Q13164	BXGT013322	Mitogen-activated protein kinase 7	5598	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13526	BXGT013369	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5300	reviewed
Q13563	BXGT013377	Polycystin-2	5311	reviewed	Ion channel
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q13887	BXGT013401	Krueppel-like factor 5	688	reviewed	Nucleic acid binding
Q14114	BXGT013441	Low-density lipoprotein receptor-related protein 8	7804	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16512	BXGT013631	Serine/threonine-protein kinase N1	5585	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q17RS7	BXGT013697	Flap endonuclease GEN homolog 1	348654	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q7Z406	BXGT017251	Myosin-14	79784	reviewed
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8WUM4	BXGT018994	Programmed cell death 6-interacting protein	10015	reviewed	Receptor
Q8WY64	BXGT019017	E3 ubiquitin-protein ligase MYLIP	29116	reviewed
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q93088	BXGT019458	Betaine--homocysteine S-methyltransferase 1	635	reviewed
Q969Q1	BXGT019610	E3 ubiquitin-protein ligase TRIM63	84676	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q99828	BXGT019967	Calcium and integrin-binding protein 1	10519	reviewed
Q9BQB6	BXGT020108	Vitamin K epoxide reductase complex subunit 1	79001	reviewed	Enzyme
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRA0	BXGT021183	Sphingosine kinase 2	56848	reviewed	Kinase
Q9NYB9	BXGT021256	Abl interactor 2	10152	reviewed	Enzyme modulator
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UIK4	BXGT021720	Death-associated protein kinase 2	23604	reviewed	Kinase
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q9ULW5	BXGT021767	Ras-related protein Rab-26	25837	reviewed
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9Y239	BXGT022213	Nucleotide-binding oligomerization domain-containing protein 1	10392	reviewed	Enzyme
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q9Y5X9	BXGT022307	Endothelial lipase	9388	reviewed	Enzyme
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
Q13007	BXGT023883	Interleukin-24	11009	reviewed
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
O43583	BXGT024866	Density-regulated protein	8562	reviewed	Enzyme
Q7L8A9	BXGT025010	Tubulinyl-Tyr carboxypeptidase 1	22846	reviewed
P27918	BXGT025485	Properdin	5199	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
Q6ZMJ2	BXGT026050	Scavenger receptor class A member 5	286133	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P78329	BXGT026166	Phylloquinone omega-hydroxylase CYP4F2	8529	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}