Showing entry for Transient receptor potential cation channel subfamily V member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004528
Protein NameTransient receptor potential cation channel subfamily V member 1
Uniport IdO35433
GeneTrpv1
Gene Id83810
DomainAnk; Ion_trans
Pfam PF12796   PF00520  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048266 behavioral response to pain
Biological Process GO:0098703 calcium ion import across plasma membrane
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0071468 cellular response to acidic pH
Biological Process GO:0071312 cellular response to alkaloid
Biological Process GO:0071318 cellular response to ATP
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0034605 cellular response to heat
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0071502 cellular response to temperature stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0050968 detection of chemical stimulus involved in sensory perception of pain
Biological Process GO:0050965 detection of temperature stimulus involved in sensory perception of pain
Biological Process GO:0050960 detection of temperature stimulus involved in thermoception
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0001660 fever generation
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0006954 inflammatory response
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0090212 negative regulation of establishment of blood-brain barrier
Biological Process GO:0010459 negative regulation of heart rate
Biological Process GO:0010917 negative regulation of mitochondrial membrane potential
Biological Process GO:0003085 negative regulation of systemic arterial blood pressure
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0002790 peptide secretion
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0060454 positive regulation of gastric acid secretion
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:1901594 response to capsazepine
Biological Process GO:0009408 response to heat
Biological Process GO:0010243 response to organonitrogen compound
Biological Process GO:0048265 response to pain
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0009268 response to pH
Biological Process GO:0050954 sensory perception of mechanical stimulus
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0060083 smooth muscle contraction involved in micturition
Biological Process GO:0001659 temperature homeostasis
Biological Process GO:0050955 thermoception
Biological Process GO:0014832 urinary bladder smooth muscle contraction
molecular function GO:0005524 ATP binding
molecular function GO:0005262 calcium channel activity
molecular function GO:0015278 calcium-release channel activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0005261 cation channel activity
molecular function GO:0008324 cation transmembrane transporter activity
molecular function GO:0017081 chloride channel regulator activity
molecular function GO:0005231 excitatory extracellular ligand-gated ion channel activity
molecular function GO:0005230 extracellular ligand-gated ion channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005216 ion channel activity
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0046872 metal ion binding
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0097603 temperature-gated ion channel activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0032591 dendritic spine membrane
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031226 intrinsic component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000665 Nonivamide 293.4
BXGC0000679 Palmidrol 299.49
BXGC0002599 2-Propene-1-sulfinothiocic-acids 2-propenyl ester 162.27
BXGC0003120 Vanillyl octanamide 279.38
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0011554 [7]-Paradol 292.41
BXGC0013447 resiniferatoxin 628.27
BXGC0013475 1,3-Dibenzylurea 240.13
BXGC0022418 evodiamine 303.14
BXGC0028278 Rutaecarpine 287.11
BXGC0032290 Anandamide 347.28
BXGC0034035 Capsaicin 305.2
BXGC0038117 Stevanil 419.34
BXGC0043126 Nicardipine 479.21
BXGC0044162 Polygodial 234.16
BXGC0049397 Olvanil 417.32
BXGC0053019 Resiniferatoxin 628.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein