Showing entry for Galanin receptor type 3



                       
General Target Information
BXGT IdBXGT004898
Protein NameGalanin receptor type 3
Uniport IdO60755
GeneGALR3
Gene Id8484
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007631 feeding behavior
Biological Process GO:0090663 galanin-activated signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0007611 learning or memory
Biological Process GO:0007194 negative regulation of adenylate cyclase activity
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
molecular function GO:0004966 galanin receptor activity
molecular function GO:0008528 G protein-coupled peptide receptor activity
molecular function GO:0017046 peptide hormone binding
cellular component GO:0005929 cilium
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0097730 non-motile cilium
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011574 BXGD000731 Involutional Depression Mental Disorders
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0027651 BXGD002009 Neoplasms Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1571983 BXGD013425 Involutional paraphrenia Mental Disorders
C1571984 BXGD013426 Psychosis, Involutional Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003102 Acetylcholine 146.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein