Showing entry for Acetylcholine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003102
Compound NameAcetylcholine
Structure
FormulaC7H16NO2
InchiKeyOIPILFWXSMYKGL-UHFFFAOYSA-N
SMILESCC(=O)OCC[N+](C)(C)C
InchiInChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
IUPAC[2-(acetyloxy)ethyl]trimethylazanium
Molecular Weight146.21
Pubchem Id187
Chembl IdCHEMBL667
Targets of Information Source
DrugBank DB03128
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE approved; investigational -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 approved; investigational -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 approved; investigational -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 approved; investigational -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 approved; investigational -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 approved; investigational -
PDB ACH
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P04058 BXGT006139 Acetylcholinesterase reviewed ache - - - - -
P21836 BXGT008694 Acetylcholinesterase reviewed Ache - - - - -
Q15485 BXGT013574 Ficolin-2 reviewed FCN2 Signaling - - - -
Q92N37 BXGT019427 Putative choline ABC transporter, periplasmic solute-binding component unreviewed choX - - - 145000 -
Q8WSF8 BXGT018982 Soluble acetylcholine receptor unreviewed - - - - -
P39075 BXGT010091 Multidrug-efflux transporter 1 regulator reviewed bmrR - - - - -
E0SJQ4 BXGT003052 Gamma-aminobutyric-acid receptor subunit beta-1 unreviewed Dda3937_00520 - - - - -
P58154 BXGT011224 Acetylcholine-binding protein reviewed - - - - -
Binding DB 10759
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R - >35000 - -
reviewed BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R - >35000 - -
reviewed BXGT011511 G protein-activated inward rectifier potassium channel 1 reviewed Kcnj3 - - - 0.06142
reviewed BXGT010325 Tropomyosin alpha-1 chain reviewed TPM1 - - - >71402
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 700 - - -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 3.4 - - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 >10000 - - -
reviewed BXGT019577 Beta-arrestin-1 reviewed ARRB1 3230 - - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 2000 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 2.66 - - -
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 347 - - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 430 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 6.8 - - -
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 >10000 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 881 - - -
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 340 - - -
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 4200 - - -
reviewed BXGT006776 Muscarinic acetylcholine receptor M3 reviewed Chrm3 2400 - - -
reviewed BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 5400 - - -
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 800 - - -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 4.2 - - -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 110 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 620 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 33 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 58 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 >10000 - - -
reviewed BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed Chrna2 11 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 56 - - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 850 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 44 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 99 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 39 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 458 -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - - - 3850 -
reviewed BXGT004898 Galanin receptor type 3 reviewed G-protein coupled receptor GALR3 - 1658 - -
reviewed BXGT004898 Galanin receptor type 3 reviewed G-protein coupled receptor GALR3 - 617.81 - -
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 820 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 41 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 83 - - -
reviewed BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed Chrnb2 11 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 45 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 270000
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 30000
reviewed BXGT005931 Acetylcholine receptor subunit delta reviewed chrnd - - - 5000
reviewed BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 8511 - - -
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 7079 - - -
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 158 - - -
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 9772 - - -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 13490 - - -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 20000
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 - - - 630
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - - - 217000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 87000
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 - - - 19000
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 100000
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 372
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - 17378 -
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 12589 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 127600
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 208930
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 205300
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 400
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 100000
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 1000
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 26
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 - - - 7
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 - - - 205
reviewed BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 - - - 49
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 - - - 19
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 19000
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 770
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 - - - 220
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 - - - 790
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 87000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 69000
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 - 24000 - -
reviewed BXGT007641 Muscarinic acetylcholine receptor M2 reviewed Chrm2 - 12 - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 230000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 155000
reviewed BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 - - - 443000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 180000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 4000
reviewed BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed Chrna3 - - - 8900
reviewed BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 - - - 144000
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 70000
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 - - - 83000
reviewed BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 - - - 1.1
reviewed BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 - - - 220
reviewed BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 - - - 3.2
reviewed BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 - - - 10
reviewed BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 - - - 1.2
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 3162.28 - - -
reviewed BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed CHRNA7 7943.28 - - -
reviewed BXGT011224 Acetylcholine-binding protein reviewed - 6309.57 - - -
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 - - - 3120
reviewed BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 - - - 1600
reviewed BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed Chrna7 170000 - - -
CHEMBL CHEMBL667
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 180000 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Smax '=' 99 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Rmax '=' 172 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Rmax '=' 172 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 100000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 100000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 400 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 400 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 4000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 3981 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 100 %
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Rmax '=' 100 %
P49582 BXGT010711 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Efficacy '=' 100 %
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 7 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Efficacy '=' 102 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 19952 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 19952 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 620 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 620 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 620 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Activity - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 20000 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 EC50 '=' 630 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Mean enhancement of binding '=' - -
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Mean enhancement of binding '=' - -
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Mean enhancement of binding '=' - -
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Mean enhancement of binding '=' - -
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Mean enhancement of binding '=' - -
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Mean enhancement of binding '=' - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Mean enhancement of binding '=' - -
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Mean enhancement of binding '=' - -
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Mean enhancement of binding '=' - -
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Mean enhancement of binding '=' - -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Mean enhancement of binding '=' - -
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 58 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 58 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 56 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Smax '=' 550 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 83 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 83 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 270000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 270000 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 48 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 820 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 820 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Bmax '=' 98 %
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 69000 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Kd2 '=' 3 uM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 8900 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 8900 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 EC50 '=' 1 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 1 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 Ratio '=' 2000 -
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 Ratio '=' 2000 -
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 Ratio '=' 2000 -
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 Ratio '=' 2000 -
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Ratio '=' 2000 -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Emax '=' 110 %
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki '=' 7079 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 13489 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki '=' 8511 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Activity '=' 1 pmol
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Relaxation '>' 50 %
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Activation '=' 100 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activation '=' 100 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Activity '=' 3 uM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 Activity '=' 3 uM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Activity '=' 0 uM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Activity '=' 0 uM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki '=' 158 nM
P23415 BXGT008864 Glycine receptor subunit alpha-1 reviewed Ion channel GLRA1 EC50 - - -
P46098 BXGT010507 5-hydroxytryptamine receptor 3A reviewed Ion channel HTR3A EC50 - - -
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 87000 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Efficacy '=' 99 %
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 25118 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Emax '=' 100 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 30000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 30000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 155000 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki '=' 9772 nM
Q63089 BXGT016060 Solute carrier family 22 member 1 reviewed - Slc22a1 Km '=' 46800 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 IC50 '=' 12 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 IC50 '=' 12 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 IC50 '=' 12 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 IC50 '=' 12 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 IC50 '=' 12 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 IC50 '=' 24000 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 IC50 '=' 24000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 IC50 '=' 24000 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 IC50 '=' 24000 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 IC50 '=' 24000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 230000 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 EC50 '=' 48 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 70000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 70000 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 83000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Max '=' 95 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Max '=' 95 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Max '=' 100 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Max '=' 100 %
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 3162 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 501 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 3120 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 87000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 87000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Enhancement '=' 73 %
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Enhancement '=' 73 %
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Enhancement '=' 73 %
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Enhancement '=' 73 %
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Enhancement '=' 73 %
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Enhancement '=' 73 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Enhancement '=' 73 %
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Enhancement '=' 73 %
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Enhancement '=' 73 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Enhancement '=' 73 %
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Enhancement '=' 73 %
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 1000000 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Bmax '=' 88 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 881 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 881 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Rmax '=' 97 %
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 8700 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 8700 nM
P10980 BXGT007641 Muscarinic acetylcholine receptor M2 reviewed - Chrm2 Ki '=' 85 nM
P08911 BXGT006839 Muscarinic acetylcholine receptor M5 reviewed - Chrm5 Ki '=' 85 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 Ki '=' 85 nM
P08483 BXGT006776 Muscarinic acetylcholine receptor M3 reviewed - Chrm3 Ki '=' 85 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Ki '=' 85 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki '=' 380 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 1905 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 12589 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 45 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 45 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 43 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 Ki '=' 43 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 Ki '=' 43 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 Ki '=' 43 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 Ki '=' 43 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 Ki '=' 43 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 43 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 43 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 43 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 43 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 43 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Kd2 '=' 2 uM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 7943 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 7943 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 70794 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 70794 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 616 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 616 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Efficacy '=' 97 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 169824 nM
Q8VH26 BXGT018927 Muscarinic acetylcholine receptor unreviewed - GPM3 Contraction '=' 50 %
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd EC50 '=' 5000 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 40000 nM
P20420 BXGT008572 Neuronal acetylcholine receptor subunit alpha-5 reviewed - Chrna5 EC50 '=' 40000 nM
P43143 BXGT010361 Neuronal acetylcholine receptor subunit alpha-6 reviewed - Chrna6 EC50 '=' 40000 nM
P12391 BXGT007811 Neuronal acetylcholine receptor subunit beta-3 reviewed - Chrnb3 EC50 '=' 40000 nM
Q9JLB5 BXGT020832 Neuronal acetylcholine receptor subunit alpha-10 reviewed - Chrna10 EC50 '=' 40000 nM
P43144 BXGT010362 Neuronal acetylcholine receptor subunit alpha-9 reviewed - Chrna9 EC50 '=' 40000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 40000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 40000 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 EC50 '=' 40000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 40000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 40000 nM
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 EC100 '=' 10 uM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 7 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 7 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 443000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 443000 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 220 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 33587 nM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 Ki '=' 7943 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 11 nM
P12389 BXGT007809 Neuronal acetylcholine receptor subunit alpha-2 reviewed - Chrna2 Ki '=' 11 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 19000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 19000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 39 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 39 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 EC50 '=' 217000 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 '=' 217000 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Max '=' 98 %
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Max '=' 98 %
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Kd '=' 17378 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 150 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Rmax '=' 150 %
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 Rmax '=' 100 %
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 27000 nM
H6TY12 BXGT003609 Nicotinic acetylcholine receptor alpha8 subunit unreviewed - EC50 '=' 11481 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 73 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 73 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Activity '=' 50 uM
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 reviewed - CHRNA7 EC50 '=' 83176 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 19000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 19000 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 EC50 '=' 10 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 3509 nM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Kd1 '=' 0 uM
P02718 BXGT005931 Acetylcholine receptor subunit delta reviewed - chrnd Kd1 '=' 0 uM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 1000 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 1000 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Imax '=' 67 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Imax '=' 67 %
P08485 BXGT006777 Muscarinic acetylcholine receptor M4 reviewed - Chrm4 EC20 '=' 15 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 3 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 1600 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 1600 nM
P12392 BXGT007812 Neuronal acetylcholine receptor subunit beta-4 reviewed - Chrnb4 Ki '=' 57 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 57 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 33 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 33 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Bmax '=' 95 %
Q9Z0E8 BXGT022397 Solute carrier family 22 member 5 reviewed - Slc22a5 Activity '=' 34 %
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 EC50 '=' 19 nM
P08909 BXGT006838 5-hydroxytryptamine receptor 2C reviewed - Htr2c Activity - - -
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 EC50 '=' 1 nM
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 EC50 '=' 1 nM
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Efficacy '=' 110 %
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Efficacy '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 25000 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 100000 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Emax '=' 100 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Drug degradation '=' 1 10'-8mol/min
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 144543 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 144543 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 144000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 144000 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Efficacy '=' 102 %
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Efficacy '=' 93 %
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 510 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki '=' 6800 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Emax '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 Ki '=' 170000 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Emax '=' 100 %
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Emax '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 205300 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 616 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki '=' 390 nM
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 reviewed Ion channel CHRNA3 EC50 '=' 127000 nM
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 reviewed Ion channel CHRNB4 EC50 '=' 127000 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 37 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 37 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Bmax '=' 100 %
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 22 nM
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 512 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Emax '=' 92 %
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Efficacy '=' 117 %
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Efficacy '=' 110 %
P58154 BXGT011224 Acetylcholine-binding protein reviewed - Ki '=' 6309 nM
P09482 BXGT006895 Neuronal acetylcholine receptor subunit alpha-4 reviewed - CHRNA4 T1/2 '=' 0 hr
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Efficacy '=' 100 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 127600 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 371 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 '=' 24000 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 EC50 '=' 24000 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Bmax '=' 98 %
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 208929 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 22908 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 23000 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 1900 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 41 nM
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 Ki '=' 41 nM
P06276 BXGT006430 Cholinesterase reviewed - BCHE Drug degradation '=' 6 10'-8mol/min
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 Ki '=' 33 nM
P09483 BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed - Chrna4 Ki '=' 33 nM
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 reviewed Ion channel CHRNA4 Imax '=' 33 %
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 reviewed Ion channel CHRNB2 Imax '=' 33 %
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki '=' 380 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 239 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 23 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 49 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 47 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki '=' 5800 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 25 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki '=' 4700 nM
P35563 BXGT009849 5-hydroxytryptamine receptor 3A reviewed - Htr3a EC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 13 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki '=' 6760 nM
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 EC50 '=' 46 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 240 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 EC50 '=' 12 nM
Q05941 BXGT012847 Neuronal acetylcholine receptor subunit alpha-7 reviewed - Chrna7 EC50 '=' 110000 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 EC50 '=' 205 nM
P12390 BXGT007810 Neuronal acetylcholine receptor subunit beta-2 reviewed - Chrnb2 EC50 - - -
P04757 BXGT006258 Neuronal acetylcholine receptor subunit alpha-3 reviewed - Chrna3 EC50 - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00040 Pepper (C. annuum) Capsicum annuum Vegetables
BXGF00061 Coriander Coriandrum sativum Herbs and Spices
BXGF00067 Cumin Cuminum cyminum Herbs and Spices
BXGF00072 Wild carrot Daucus carota Vegetables
BXGF00073 Japanese persimmon Diospyros kaki Fruits
BXGF00074 Cardamom Elettaria cardamomum Herbs and Spices
BXGF00082 Fennel Foeniculum vulgare Herbs and Spices
BXGF00137 Anise Pimpinella anisum Herbs and Spices
BXGF00139 Pepper (Spice) Piper nigrum Herbs and Spices
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00178 Spinach Spinacia oleracea Vegetables
BXGF00186 Fenugreek Trigonella foenum-graecum Herbs and Spices
BXGF00230 Carrot Daucus carota ssp. sativus Vegetables
BXGF00351 Jackfruit Artocarpus heterophyllus Fruits
BXGF00818 Herbs and Spices Herbs and Spices
BXGF00823 Fruits Fruits
BXGF00829 Green bell pepper Capsicum annuum Vegetables
BXGF00830 Yellow bell pepper Capsicum annuum Vegetables
BXGF00831 Orange bell pepper Capsicum annuum Vegetables
BXGF00832 Red bell pepper Capsicum annuum Vegetables
BXGF01283 Crataegus pinnatifida Crataegus pinnatifida Medicinal Plant
BXGF02317 Krameria parvifolia Krameria parvifolia Others
BXGF02372 Aesculus turbinata Aesculus turbinata Medicinal Plant
BXGF02390 Argyreia speciosa Argyreia speciosa Medicinal Plant
BXGF02465 Vernonia profuga Vernonia profuga Others
BXGF02578 Artocarpus styracifolius Artocarpus styracifolius Human Edible Plant
BXGF02779 Swertia chinensis Swertia chinensis Medicinal Plant
BXGF02821 Forsythia giraldiana Forsythia giraldiana Others
BXGF02892 Dorstenia mannii Dorstenia mannii Medicinal Plant
BXGF03398 Solanum nigrum Solanum nigrum Medicinal Plant
BXGF03560 Alnus alnobetula Alnus alnobetula Others
BXGF04238 Capsella bursa-pastoris Capsella bursa-pastoris Medicinal Plant
BXGF05819 Citrus aurantium Citrus aurantium Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease