Showing entry for Structural maintenance of chromosomes protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005374
Protein NameStructural maintenance of chromosomes protein 2
Uniport IdO95347
GeneSMC2
Gene Id10592
DomainSMC_hinge; SMC_N
Pfam PF06470   PF02463  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0051383 kinetochore organization
Biological Process GO:0010032 meiotic chromosome condensation
Biological Process GO:0045132 meiotic chromosome segregation
Biological Process GO:0007076 mitotic chromosome condensation
molecular function GO:0005524 ATP binding
cellular component GO:0000793 condensed chromosome
cellular component GO:0000796 condensin complex
cellular component GO:0000797 condensin core heterodimer
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0000228 nuclear chromosome
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-1640170 Cell Cycle
R-HSA-2299718 Condensation of Prophase Chromosomes
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-68875 Mitotic Prophase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005890 BXGD000345 Body Height
C0007117 BXGD000433 Basal cell carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029121 BXGD002112 Oppositional Defiant Disorder Mental Disorders
C0029877 BXGD002175 Ear Inflammation Otorhinolaryngologic Diseases
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0029883 BXGD002178 Otitis Media with Effusion Otorhinolaryngologic Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036363 BXGD002607 Schizotypal Personality Disorder Mental Disorders
C0206710 BXGD004258 Basal Cell Neoplasm Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0270549 BXGD006079 Generalized Anxiety Disorder Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0525041 BXGD009254 Neurobehavioral Manifestations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699744 BXGD009863 Infection of ear Otorhinolaryngologic Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751676 BXGD010549 Basal Cell Cancer Neoplasms
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0860603 BXGD011236 Anxiety symptoms
C0871189 BXGD011312 Psychotic symptom
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1709781 BXGD013633 Pyothorax-Associated Lymphoma
C2827407 BXGD017795 Infectious Otitis Media Otorhinolaryngologic Diseases
C3160814 BXGD018477 Cannabis use
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein